Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice

Nature ◽

10.1038/315676a0 ◽

1985 ◽

Vol 315 (6021) ◽

pp. 676-679 ◽

Author(s):

Yannick Le Marchand-Brustel ◽

Thierry Grémeaux ◽

Robert Ballotti ◽

Emmanuel Van Obberghen

Keyword(s):

Skeletal Muscle ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Resistant

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Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects

Diabetologia ◽

10.1007/bf02369353 ◽

1995 ◽

Vol 38 (1) ◽

pp. 55-61 ◽

Author(s):

G. Grasso ◽

L. Frittitta ◽

M. Anello ◽

P. Russo ◽

G. Sesti ◽

...

Keyword(s):

Adipose Tissue ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Resistant

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Insulin receptor tyrosine kinase activity is reduced in monocytes from non-obese normoglycaemic insulin-resistant subjects

Diabetologia ◽

10.1007/bf00401061 ◽

1993 ◽

Vol 36 (11) ◽

pp. 1163-1167 ◽

Author(s):

L. Frittitta ◽

G. Grasso ◽

M. E. Munguira ◽

R. Vigneri ◽

V. Trischitta

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Resistant

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Phosphorylation of insulin-like growth factor I receptor by the insulin receptor tyrosine kinase in intact cultured skeletal muscle cells

Biochemistry ◽

10.1021/bi00409a015 ◽

1988 ◽

Vol 27 (9) ◽

pp. 3222-3228 ◽

Author(s):

Francesco Beguinot ◽

Robert J. Smith ◽

C. Ronald Kahn ◽

Ruth Maron ◽

Alan C. Moses ◽

...

Keyword(s):

Skeletal Muscle ◽

Growth Factor ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Muscle Cells ◽

Skeletal Muscle Cells ◽

Insulin Like Growth Factor ◽

Insulin Receptor Tyrosine Kinase ◽

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PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity

Diabetologia ◽

10.1007/bf02658505 ◽

1996 ◽

Vol 39 (10) ◽

pp. 1190-1195 ◽

Author(s):

L. Frittitta ◽

J. Youngren ◽

R. Vigneri ◽

B. A. Maddux ◽

V. Trischitta ◽

...

Keyword(s):

Skeletal Muscle ◽

Insulin Sensitivity ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase

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Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects

Diabetologia ◽

10.1007/s001250050253 ◽

1995 ◽

Vol 38 (1) ◽

pp. 55-61 ◽

Author(s):

G. Grasso ◽

L. Frittitta ◽

M. Anello ◽

P. Russo ◽

G. Sesti ◽

...

Keyword(s):

Adipose Tissue ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Resistant

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Insulin receptor tyrosine kinase activity is unaltered in ob/ob and db/db mouse skeletal muscle membranes

Life Sciences ◽

10.1016/0024-3205(87)90201-3 ◽

1987 ◽

Vol 41 (10) ◽

pp. 1233-1241 ◽

Author(s):

P. Vicario ◽

E.J. Brady ◽

E.E. Slater ◽

R. Saperstein

Keyword(s):

Skeletal Muscle ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Mouse Skeletal Muscle

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Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity

Acta Endocrinologica ◽

10.1530/acta.0.114s183 ◽

1987 ◽

Vol 116 (3_Suppl) ◽

pp. S183

Author(s):

H.H. KLEIN ◽

G.R. FREIDENBERG ◽

R.R. HENRY ◽

J.M. OLEFSKY

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Insulin Dependent Diabetes ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Dependent

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Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells

Diabetes ◽

10.2337/diabetes.40.11.1440 ◽

1991 ◽

Vol 40 (11) ◽

pp. 1440-1448 ◽

Author(s):

H. K. Muller ◽

M. Kellerer ◽

B. Ermel ◽

A. Muhlhofer ◽

B. Obermaier-Kusser ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Fat Cells ◽

Insulin Receptor Tyrosine Kinase ◽

Protein Kinase C Inhibitors ◽

Kinase C ◽

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Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats

Diabetes ◽

10.2337/diabetes.39.5.619 ◽

1990 ◽

Vol 39 (5) ◽

pp. 619-625 ◽

Author(s):

L. J. Slieker ◽

E. F. Roberts ◽

W. N. Shaw ◽

W. T. Johnson

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Zucker Rats ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Obese Zucker Rats

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pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54060-6 ◽

1993 ◽

Vol 268 (2) ◽

pp. 1201-1206 ◽

Author(s):

S.M. Najjar ◽

D. Accili ◽

N. Philippe ◽

J. Jernberg ◽

R. Margolis ◽

...

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Endogenous Substrate

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