scholarly journals Diagnostic Ionizing Radiation Exposure in a Population-Based Sample of Children With Inflammatory Bowel Diseases

2009 ◽  
Vol 104 (11) ◽  
pp. 2816-2823 ◽  
Author(s):  
Lena Palmer ◽  
Hans Herfarth ◽  
Carol Q Porter ◽  
Lynn A Fordham ◽  
Robert S Sandler ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Inflammatory Bowel Diseases ◽  
Population Based ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Ionizing Radiation Exposure

scholarly journals Diagnostic Ionizing Radiation Exposure in a Population-Based Cohort of Patients with Inflammatory Bowel Disease

2008 ◽  
Vol 103 (8) ◽  
pp. 2015-2022 ◽  
Author(s):  
Joanna M. Peloquin ◽  
Darrell S. Pardi ◽  
William J. Sandborn ◽  
Joel G. Fletcher ◽  
Cynthia H. McCollough ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Bowel Disease ◽  
Population Based ◽  
Inflammatory Bowel ◽  
Ionizing Radiation Exposure

scholarly journals Utilization of Diagnostic Imaging and Ionizing Radiation Exposure—Has the Tide Already Turned?

2019 ◽  
Vol 26 (6) ◽  
pp. 907-908
Author(s):  
Sebastian Zundler
Keyword(s):  
Ionizing Radiation ◽  
Diagnostic Imaging ◽  
Radiation Exposure ◽  
Case Control Study ◽  
Management Of Complications ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Ionizing Radiation Exposure ◽  
Control Study

Abstract Inflammatory bowel diseases require repetitive abdominal imaging for diagnosis, follow-up, or management of complications. This editorial comments on the large incident-based case–control study on utilization of diagnostic imaging and ionizing radiation exposure by Nguyen and colleagues published in this issue.

scholarly journals P295 VALIDation of the IBD-Disk instrument for assessing disability in inflammatory bowel diseases in a population-based cohort: The VALIDate study

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S299-S301
Author(s):  
C Le Berre ◽  
A Bourreille ◽  
M Flamant ◽  
G Bouguen ◽  
L Siproudhis ◽  
...  
Keyword(s):  
Internal Consistency ◽  
Inflammatory Bowel Diseases ◽  
Population Based ◽  
Large Cohort ◽  
Inactive Disease ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Physician Patient ◽  
Over Time

Abstract Background Inflammatory bowel diseases (IBD) are disabling disorders. The IBD-Disability Index (IBD-DI) was developed for quantifying disability in IBD patients but is difficult to use. The IBD-Disk is a shortened and visual adaptation of the IBD-DI. It has not been validated yet. The main objectives were to validate the IBD-Disk in a large cohort of IBD patients and to assess its variability over time. Methods From March 2018 to July 2019, IBD patients from three university-affiliated hospitals responded twice to both IBD-Disk and IBD-DI at 3–12 months intervals (NCT03590639). Validation included concurrent validity, reproducibility, internal consistency, and evaluation of IBD-Disk correlation with IBD activity. Variability was assessed by comparing scores between baseline and follow-up visits. Results A total of 559 patients (73% Crohn’s disease, 27% ulcerative colitis) were included and 389 were followed up (Table 1). There was a good correlation between IBD-Disk and IBD-DI scores (r = 0.75, p < 0.001) (Figure 1). The IBD-Disk was significantly higher in patients with active disease according to Physician/Patient Global Assessment (Figure 2), clinical scores (Figure 3), and biomarkers levels, compared with patients with inactive disease. Reproducibility was excellent (intra-class correlation coefficient = 0.90), as well as internal consistency (Cronbach’s α = 0.89). The IBD-Disk score significantly decreased in patients becoming inactive over time. Conclusion This is the first study to validate the IBD-Disk in a large cohort of IBD patients, demonstrating that it is a valid and reliable tool for quantifying disability in clinical practice. Further studies are warranted to assess its correlation with endoscopic activity, to explore its responsiveness to change, and to evaluate the factors associated with disability.

scholarly journals Sa1769 – Worldwide Incidence of Older-Onset Inflammatory Bowel Diseases in the 21ST Century: A Systematic Review of Population-Based Studies

2019 ◽  
Vol 156 (6) ◽  
pp. S-394-S-395 ◽  
Author(s):  
Siddharth Singh ◽  
Fox E. Underwood ◽  
Edward V. Loftus ◽  
Parambir S. Dulai ◽  
Subrata Ghosh ◽  
...  
Keyword(s):  
Systematic Review ◽  
21St Century ◽  
Inflammatory Bowel Diseases ◽  
Population Based ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals P803 The risk of spine and hip fracture in patients with inflammatory bowel diseases: a nationwide population-based study

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S629-S629
Author(s):  
Y J Kim ◽  
H J Ahn ◽  
S Noh ◽  
J C Park ◽  
J Y Kim ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Regression Model ◽  
Incidence Rate ◽  
Inflammatory Bowel Diseases ◽  
Cox Regression ◽  
Population Based ◽  
Population Based Study ◽  
Cox Regression Model ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Abstract Background This nationwide population-based study sought to investigate the risk of spine and hip fracture in patients with inflammatory bowel diseases (IBD). Methods Using the 2007–2016 data from the Korean national health insurance claims database, we calculated incidence rate and incidence rate ratios (IRR) of spine and hip fracture in patients with IBD (n = 18,228; 64.1% male, 65.9% ulcerative colitis [UC]) compared with age- and sex- frequency matched subjects in 1:10 ratio (n = 186,871). A Cox regression model was used to evaluate risk of spine and hip fracture. Results The incidence rate and IRR of spine and hip fracture in IBD were 2.88/1000 person-years and 1.21 (95% confidence interval [CI], 1.11–1.31) during the median follow-up of 4.5 years. The risk for spine and hip fracture was significantly higher in UC (IRR 1.39, 95% CI, 1.25- 1.54), whereas it was not significantly higher in Crohn’s disease (IRR 0.85, 95% CI, 0.67- 1.06) than matched controls. In UC, the IRR of spine fracture was 1.41 (95% CI, 1.24–1.58) and the IRR of hip fracture was 1.40 (95% CI, 1.11–1.71). In multivariable analysis using the Cox regression model, the risk of spine and hip fracture increased with age (p trend < 0.001), in female patients (adjusted hazard ratio [aHR], 1.94; 95% CI, 1.50–2.51) and in patients with comorbidities including osteoporosis (aHR 2.86; 95% CI, 2.10–3.89), stroke (aHR 2.74; 95% CI, 1.78–4.21) hypertension (aHR 1.82; 95% CI, 1.38–2.41), diabetes mellitus (aHR 1.67; 95% CI, 1.25–2.24) and dyslipidaemia (aHR 1.36; 95% CI, 1.05–1.78). Conclusion In a population-based study from Korea, we found that the risk for spine and hip fracture increased in patients with IBD, especially in UC patients. Also, this risk increased in patients who are older, female, or have comorbidities.

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