scholarly journals Mediterranean diet and colorectal cancer risk: a pooled analysis of three Italian case–control studies

2016 ◽  
Vol 115 (7) ◽  
pp. 862-865 ◽  
Author(s):  
Valentina Rosato ◽  
Valentina Guercio ◽  
Cristina Bosetti ◽  
Eva Negri ◽  
Diego Serraino ◽  
...  
2017 ◽  
Vol 69 (5) ◽  
pp. 732-738 ◽  
Author(s):  
Valentina Rosato ◽  
Alessandra Tavani ◽  
Eva Negri ◽  
Diego Serraino ◽  
Maurizio Montella ◽  
...  

2015 ◽  
Vol 19 (2) ◽  
pp. 308-317 ◽  
Author(s):  
Manuela Chiavarini ◽  
Liliana Minelli ◽  
Roberto Fabiani

AbstractObjectiveColorectal cancer shows large incidence variations worldwide that have been attributed to different dietary factors. We conducted a meta-analysis on the relationship between garlic consumption and colorectal cancer risk.DesignWe systematically reviewed publications obtained by searching ISI Web of Knowledge, MEDLINE and EMBASE literature databases. We extracted the risk estimate of the highest and the lowest reported categories of intake from each study and conducted meta-analysis using a random-effects model.ResultsThe pooled analysis of all fourteen studies, seven cohort and seven case–control, indicated that garlic consumption was not associated with colorectal cancer risk (OR=0·93; 95 % CI 0·82, 1·06, P=0·281; I2=83·6 %, P≤0·001). Separate analyses on the basis of cancer sites and sex also revealed no statistically significant effects on cancer risk. However, when separately analysed on the basis of study type, we found that garlic was associated with an approximately 37 % reduction in colorectal cancer risk in the case–control studies (combined risk estimate=0·63, 95 % CI 0·48, 0·82, P=0·001; I2=75·6 %, P≤0·001).ConclusionsOur results suggest that consumption of garlic is not associated with a reduced colorectal cancer risk. Further investigations are necessary to clarify the discrepancy between results obtained from different types of epidemiological studies.


2016 ◽  
Vol 6 ◽  
Author(s):  
Valentina Rosato ◽  
Alessandra Tavani ◽  
Esther Gracia-Lavedan ◽  
Elisabet Guinó ◽  
Gemma Castaño-Vinyals ◽  
...  

Oncotarget ◽  
2016 ◽  
Vol 7 (46) ◽  
pp. 75561-75570 ◽  
Author(s):  
Yongsheng Huang ◽  
Wenting Wu ◽  
Meng Nie ◽  
Chuang Li ◽  
Lin Wang

2018 ◽  
Vol 92 (3) ◽  
pp. 347-359 ◽  
Author(s):  
Veronica Sciannameo ◽  
Angela Carta ◽  
Angelo d’Errico ◽  
Maria Teresa Giraudo ◽  
Francesca Fasanelli ◽  
...  

2012 ◽  
Vol 40 (6) ◽  
pp. 3943-3952 ◽  
Author(s):  
Li Liu ◽  
Lin Miao ◽  
Guozhong Ji ◽  
Fulin Qiang ◽  
Zheng Liu ◽  
...  

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