scholarly journals Structural insights into Ca2+-activated long-range allosteric channel gating of RyR1

Cell Research ◽  
2016 ◽  
Vol 26 (9) ◽  
pp. 977-994 ◽  
Author(s):  
Risheng Wei ◽  
Xue Wang ◽  
Yan Zhang ◽  
Saptarshi Mukherjee ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Long Range ◽  
Channel Gating ◽  
Structural Insights

Modeling the Closed and Open State Conformations of the GABAAIon Channel - Plausible Structural Insights for Channel Gating

2012 ◽  
Vol 52 (11) ◽  
pp. 2958-2969 ◽  
Author(s):  
R. S. K. Vijayan ◽  
Neha Trivedi ◽  
Sudipendra Nath Roy ◽  
Indrani Bera ◽  
Prabu Manoharan ◽  
...  
Keyword(s):  
Channel Gating ◽  
Structural Insights

scholarly journals Surfactant-directed syntheses of mesostructured zinc imidazolates: formation mechanism and structural insights

CrystEngComm ◽  
2015 ◽  
Vol 17 (2) ◽  
pp. 463-470 ◽  
Author(s):  
E. A. Flügel ◽  
M. T. Aronson ◽  
S. C. Junggeburth ◽  
B. F. Chmelka ◽  
B. V. Lotsch
Keyword(s):  
Long Range ◽  
Formation Mechanism ◽  
Lamellar Zinc ◽  
Structural Insights

A detailed study on the formation mechanism, local and long-range structures of surfactant-directed lamellar zinc imidazolates is presented.

scholarly journals New Structural insights into Kir channel gating from molecular simulations, HDX-MS and functional studies

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Charline Fagnen ◽  
Ludovic Bannwarth ◽  
Iman Oubella ◽  
Eric Forest ◽  
Rita De Zorzi ◽  
...  
Keyword(s):  
Channel Gating ◽  
Molecular Simulations ◽  
Functional Studies ◽  
Kir Channel ◽  
Hdx Ms ◽  
Structural Insights

Structural Insights into TRPV Channel Gating

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Vera Moiseenkova-Bell
Keyword(s):  
Channel Gating ◽  
Structural Insights

scholarly journals Structural Insights into RNA Dimerization: Motifs, Interfaces and Functions

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2881 ◽  
Author(s):  
Charles Bou-Nader ◽  
Jinwei Zhang
Keyword(s):  
Long Range ◽  
Meta Analysis ◽  
Immune Surveillance ◽  
Rna Dimerization ◽  
Protein Dimers ◽  
Domains Of Life ◽  
Stress Sensing ◽  
A Minor ◽  
Structural Insights ◽  
Functional Rna

In comparison with the pervasive use of protein dimers and multimers in all domains of life, functional RNA oligomers have so far rarely been observed in nature. Their diminished occurrence contrasts starkly with the robust intrinsic potential of RNA to multimerize through long-range base-pairing (“kissing”) interactions, self-annealing of palindromic or complementary sequences, and stable tertiary contact motifs, such as the GNRA tetraloop-receptors. To explore the general mechanics of RNA dimerization, we performed a meta-analysis of a collection of exemplary RNA homodimer structures consisting of viral genomic elements, ribozymes, riboswitches, etc., encompassing both functional and fortuitous dimers. Globally, we found that domain-swapped dimers and antiparallel, head-to-tail arrangements are predominant architectural themes. Locally, we observed that the same structural motifs, interfaces and forces that enable tertiary RNA folding also drive their higher-order assemblies. These feature prominently long-range kissing loops, pseudoknots, reciprocal base intercalations and A-minor interactions. We postulate that the scarcity of functional RNA multimers and limited diversity in multimerization motifs may reflect evolutionary constraints imposed by host antiviral immune surveillance and stress sensing. A deepening mechanistic understanding of RNA multimerization is expected to facilitate investigations into RNA and RNP assemblies, condensates, and granules and enable their potential therapeutical targeting.

scholarly journals Structural Insights into TRPV Channel Gating

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Vera Moiseenkova‐Bell
Keyword(s):  
Channel Gating ◽  
Structural Insights

Generalized normolipemic plane xanthoma. New observations and long-range follow-up

1981 ◽  
Vol 117 (8) ◽  
pp. 521-522 ◽  
Author(s):  
R. J. Thomsen
Keyword(s):  
Long Range

Electron-hole long-range exchange interaction in semiconductor quantum dots

1998 ◽  
Vol 184-185 (1-2) ◽  
pp. 393-397 ◽  
Author(s):  
S Goupalov
Keyword(s):  
Quantum Dots ◽  
Exchange Interaction ◽  
Long Range ◽  
Semiconductor Quantum Dots ◽  
Electron Hole
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