scholarly journals Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism

2015 ◽  
Vol 24 (1) ◽  
pp. 142-145 ◽  
Author(s):  
Mattijs M Heemskerk ◽  
Vanessa JA van Harmelen ◽  
Ko Willems van Dijk ◽  
Jan Bert van Klinken
Keyword(s):  
Amino Acid ◽  
Lactate Dehydrogenase ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Branched Chain Amino Acid ◽  
Branched Chain

scholarly journals Branched-chain amino acid metabolism and alanine formation in rat diaphragm muscle in vitro. Effects of dichloroacetate

1984 ◽  
Vol 223 (3) ◽  
pp. 831-835 ◽  
Author(s):  
K Snell ◽  
D A Duff
Keyword(s):  
Amino Acid ◽  
Pyruvate Dehydrogenase ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Diaphragm Muscle ◽  
Rat Diaphragm ◽  
Branched Chain Amino Acid ◽  
In Vitro Effects ◽  
Branched Chain

Dichloroacetate (which activates pyruvate dehydrogenase) decreases the release of alanine, pyruvate and lactate in hemidiaphragm incubations with valine. Dichloroacetate interferes with alanine formation by diverting pyruvate into oxidative pathways, which not only limits pyruvate availability for direct transamination to form alanine but also indirectly affects branched-chain amino acid transamination by limiting 2-oxoglutarate regeneration from glutamate.

scholarly journals Altered branched chain amino acid metabolism

2018 ◽  
Vol 33 (5) ◽  
pp. 558-564 ◽  
Author(s):  
Deirdre K. Tobias ◽  
Samia Mora ◽  
Subodh Verma ◽  
Patrick R. Lawler
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Branched Chain Amino Acid ◽  
Branched Chain

scholarly journals Short communication: Colostrum versus formula: Effects on mRNA expression of genes related to branched-chain amino acid metabolism in neonatal dairy calves

2020 ◽  
Vol 103 (10) ◽  
pp. 9656-9666 ◽  
Author(s):  
Morteza H. Ghaffari ◽  
Hassan Sadri ◽  
Harald M. Hammon ◽  
Julia Steinhoff-Wagner ◽  
Nico Henschel ◽  
...  
Keyword(s):  
Amino Acid ◽  
Mrna Expression ◽  
Amino Acid Metabolism ◽  
Short Communication ◽  
Acid Metabolism ◽  
Dairy Calves ◽  
Branched Chain Amino Acid ◽  
Expression Of Genes ◽  
Branched Chain

scholarly journals Pancreatic stellate cells regulate branched-chain amino acid metabolism in pancreatic cancer

2021 ◽  
Vol 9 (5) ◽  
pp. 417-417
Author(s):  
Wenna Jiang ◽  
Lu Qiao ◽  
Yawei Han ◽  
Aimin Zhang ◽  
Haohua An ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Stellate Cells ◽  
Pancreatic Stellate Cells ◽  
Branched Chain Amino Acid ◽  
Branched Chain
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