Time-to-delivery and delivery outcomes comparing three methods of labor induction in 7551 nulliparous women: a population-based cohort study

Abstract Background: Our objective was to evaluate risks of adverse obstetric outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy. Methods: We analyzed the national health insurance database, which covers almost the entire Korean population, between 2004 and 2015. The risks of adverse pregnancy outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy, compared to those in women without a diagnosed myoma, were analyzed in multivariate logistic regression analysis. Results: During the study period, 38,402 women with diagnosed myoma(s), 9,890 women with a history of myomectomy, and 740,675 women without a diagnosed myoma gave birth. Women with a history of diagnosed myoma(s) and women with a history of myomectomy had significantly higher risks of cesarean section (aOR 1.13, 95% CI 1.1-1.16 and aOR 7.46, 95% CI 6.97-7.98, respectively) and placenta previa (aOR 1.41, 95% CI 1.29-1.54 and aOR 1.58, 95% CI 1.35-1.83, respectively), compared to women without a diagnosed myoma. And the risk of uterine rupture was significantly higher in women with previous myomectomy (aOR 12.78, 95% CI 6.5-25.13), compared to women without a diagnosed myoma, which was much increased (aOR 41.35, 95% CI 16.18-105.69) in nulliparous women. The incidence of uterine rupture was the highest at delivery within one year after myomectomy and decreased over time after myomectomy. Conclusions: Women with a history of myomectomy had significantly higher risks of cesarean section and placenta previa compared to women without a diagnosed myoma.

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Transvaginal sonographic assessment of the cervix for prediction of successful induction of labor in nulliparous women

QJM ◽

10.1093/qjmed/hcab115.022 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Mohammed Abd-Elhameed Abd-Elhafeez ◽

Alaa Eldin Elguindy ◽

Mohamed Abu El Fetoh Mohamed Hamed ◽

Maii Nawara

Keyword(s):

Cohort Study ◽

Significant Positive Correlation ◽

Transvaginal Ultrasound ◽

Significant Negative Correlation ◽

Cervical Length ◽

Labor Induction ◽

Induction Of Labor ◽

Cutoff Value ◽

Nulliparous Women ◽

Successful Induction

Abstract Background Induction of labor is commonly performed in obstetric practice. Many methods have been suggested as good predictors of the outcome of labor induction, yet none of them is satisfactory enough. Objective To assess cervical length and uterocervical angle measured by transvaginal ultrasound as predictors of successful induction of labor. Methodology Prospective cohort study was conducted in a university-affiliated hospital over 150 nulliparous women undergoing induction of labor, in the period between May 2018 and August 2019. Transvaginal sonographic measurement of cervical length and uterocervical angle was done before induction of labor by prostaglandins. The patients were followed up till delivery and the outcome was recorded. Results The best cut-off value of cervical length for prediction of success of labor induction was 32.3 mm with 60% sensitivity and 56% specificity and the best cutoff value of uterocervical angle was 110.2 degrees with 87% sensitivity and 93% specificity. The cervical length showed a significant negative correlation while the uterocervical angle showed a significant positive correlation with the success of labor induction. Conclusion Cervical length and uterocervical angle are good predictors of successful labor induction.

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Placental location and pregnancy outcomes in nulliparous women: A population‐based cohort study

Acta Obstetricia Et Gynecologica Scandinavica ◽

10.1111/aogs.13578 ◽

2019 ◽

Vol 98 (8) ◽

pp. 988-996 ◽

Cited By ~ 5

Author(s):

Michaela Granfors ◽

Olof Stephansson ◽

Margit Endler ◽

Maria Jonsson ◽

Anna Sandström ◽

...

Keyword(s):

Cohort Study ◽

Pregnancy Outcomes ◽

Population Based ◽

Nulliparous Women

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Postpartum haemorrhage in nulliparous women: incidence and risk factors in low and high risk womenA Dutch population-based cohort study on standard (≥500 ml) and severe (≥1000 ml) postpartum haemorrhage

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/s0301-2115(03)00639-0 ◽

2004 ◽

Vol 115 (2) ◽

pp. 166-172 ◽

Cited By ~ 34

Author(s):

J BAIS ◽

M ESKES ◽

M PEL ◽

G BONSEL ◽

O BLEKER

Keyword(s):

Risk Factors ◽

Cohort Study ◽

High Risk ◽

Postpartum Haemorrhage ◽

Population Based ◽

Dutch Population ◽

Nulliparous Women

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Reproductive Factors and Risk of Systemic Lupus Erythematosus: Nationwide Cohort Study in Denmark

The Journal of Rheumatology ◽

10.3899/jrheum.090002 ◽

2009 ◽

Vol 36 (9) ◽

pp. 1903-1909 ◽

Cited By ~ 26

Author(s):

CONSTANCE J. ULFF-MØLLER ◽

KRISTIAN T. JØRGENSEN ◽

BO V. PEDERSEN ◽

NETE M. NIELSEN ◽

MORTEN FRISCH

Keyword(s):

Systemic Lupus Erythematosus ◽

Cohort Study ◽

Lupus Erythematosus ◽

Lower Risk ◽

Reproductive Factors ◽

Population Based ◽

Spontaneous Abortions ◽

Contributing Factors ◽

Systemic Lupus ◽

Nulliparous Women

Objective.The female predominance in systemic lupus erythematosus (SLE) suggests the possible involvement of reproductive factors in its etiology. We evaluated the relationship between parity and pregnancy losses and subsequent risk of SLE in a population-based cohort study.Methods.We followed 4.4 million Danes aged 15–69 years for first inpatient hospitalizations for SLE between 1977 and 2004. As measures of relative risk, we used Poisson regression-derived hospitalization rate ratios (RR) with 95% confidence intervals (CI) for cohort members with different reproductive histories.Results.Overall, 1614 women and 274 men were hospitalized with SLE during 88.9 million person-years of followup. Number of children was unrelated to SLE risk in men, but women with at least one liveborn child were at lower risk than nulliparous women (RR 0.74; 95% CI 0.64–0.86), and women with 2 or more children were at lower risk than 1-child mothers. Recurrent idiopathic pregnancy losses, including spontaneous abortions, missed abortions, and stillbirths, were associated with markedly increased SLE risk (RR 3.50; 95% CI 2.38–4.96, for 2+ vs none; p < 0.001).Conclusion.Nulliparous women, 1-child mothers, and women who experience spontaneous abortions, missed abortions, or stillbirths are at increased SLE risk. Theoretically, immunological processes involved in subfertility or idiopathic pregnancy losses might act as initiating or contributing factors in some cases of SLE. However, considering the well established excess of pregnancy complications in women with established SLE, the observed associations more likely reflect the effect of subclinical immunological processes in women destined to develop SLE.

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Outcome after elective labor induction in nulliparous women: A matched cohort study

American Journal of Obstetrics and Gynecology ◽

10.1067/mob.2002.119643 ◽

2002 ◽

Vol 186 (2) ◽

pp. 240-244 ◽

Cited By ~ 123

Author(s):

Hendrik Cammu ◽

Guy Martens ◽

Gunther Ruyssinck ◽

Jean-Jacques Amy

Keyword(s):

Cohort Study ◽

Labor Induction ◽

Matched Cohort ◽

Matched Cohort Study ◽

Nulliparous Women

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Risk of cesarean delivery in ongoing pregnancies of nulliparous women after 37 weeks of gestation: a prospective cohort study

10.22541/au.163253033.36490819/v1 ◽

2021 ◽

Author(s):

Thibaud Quibel ◽

Camille Bouyer ◽

Patrick Rozenberg ◽

Jean Bouyer

Keyword(s):

Cohort Study ◽

Regression Models ◽

Outcome Measure ◽

Population Based ◽

Maternal Characteristics ◽

Nulliparous Women ◽

Perinatal Network ◽

Gestational Week ◽

Labor Onset ◽

Caesarean Delivery Rate

Objective: To study the risk of CD for each gestational week among ongoing pregnancies of nulliparous women at term. Design: A retrospective, population-based cohort study from January 1, 2016, through December 31, 2017 Setting: a French perinatal network of the Yvelines district, France Population: 11 308 nulliparous women with a singleton fetus in a cephalic presentation and delivered at term (≥37-week +0 day) Methods: for each week of gestation at term, we defined ongoing pregnancies as all pregnancies undelivered at the start of each week. Regression models adjusted by maternal characteristics and hospital status were used to compare the CD risk between ongoing pregnancies and the pregnancies delivered the preceding week. The same methods were applied to subgroups defined by the mode of labor onset. Main outcome measure: The caesarean delivery rate (CD) Results: Ongoing pregnancies > 40 weeks+0 days were associated with a higher risk of CD compared with pregnancies delivered the previous week: 24.3% in ongoing pregnancies ≥ 40 weeks +0 days versus 19.9% in deliveries between 39 weeks +0 days and 39 weeks+6 days (Odd ratio adjusted of 1.28, 95%CI [1.15-1.44]; 30.4% in ongoing pregnancies ≥ 41 weeks +0 days versus 19.6% in deliveries between 40 weeks +0 days and 40 weeks+6 days (OR 1.73, 95%CI [1.51-1.96]). This was also shown for all modes of labor onset and in every maternity unit. Conclusions: CD rates increased starting at 40 weeks +0 days in ongoing pregnancies, regardless of the mode of labor onset.

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Nationwide population-based cohort study of adverse obstetric outcomes in pregnancies with myoma or following myomectomy: Retrospective cohort study

10.21203/rs.3.rs-27382/v2 ◽

2020 ◽

Author(s):

Se Jin Lee ◽

Hyun Sun Ko ◽

Sunghun Na ◽

Jin Young Bae ◽

Won Joon Seong ◽

...

Keyword(s):

Cohort Study ◽

Cesarean Section ◽

Uterine Rupture ◽

Placenta Previa ◽

Multivariate Logistic Regression Analysis ◽

Population Based ◽

Obstetric Outcomes ◽

Nulliparous Women ◽

History Of ◽

Adverse Pregnancy

Abstract Background: Our objective was to evaluate risks of adverse obstetric outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy.Methods: We analyzed the national health insurance database, which covers almost the entire Korean population, between 2004 and 2015. The risks of adverse pregnancy outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy, compared to those in women without a diagnosed myoma, were analyzed in multivariate logistic regression analysis.Results: During the study period, 38,402 women with diagnosed myoma(s), 9,890 women with a history of myomectomy, and 740,675 women without a diagnosed myoma gave birth. Women with a history of diagnosed myoma(s) and women with a history of myomectomy had significantly higher risks of cesarean section (aOR 1.13, 95% CI 1.1-1.16 and aOR 7.46, 95% CI 6.97-7.98, respectively) and placenta previa (aOR 1.41, 95% CI 1.29-1.54 and aOR 1.58, 95% CI 1.35-1.83, respectively), compared to women without a diagnosed myoma. And the risk of uterine rupture was significantly higher in women with previous myomectomy (aOR 12.78, 95% CI 6.5-25.13), compared to women without a diagnosed myoma, which was much increased (aOR 41.35, 95% CI 16.18-105.69) in nulliparous women. The incidence of uterine rupture was the highest at delivery within one year after myomectomy and decreased over time after myomectomy. Conclusions: Women with a history of myomectomy had significantly higher risks of cesarean section and placenta previa compared to women without a diagnosed myoma.

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