Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

Nature Neuroscience ◽

10.1038/nn.3425 ◽

2013 ◽

Vol 16 (7) ◽

pp. 780-789 ◽

Author(s):

Jackson Sandoe ◽

Kevin Eggan

Keyword(s):

Stem Cell ◽

Neurodegenerative Disease ◽

Pluripotent Stem Cell ◽

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Isogenic human pluripotent stem cell disease models reveal ABRA deficiency underlies cTnT mutation-induced familial dilated cardiomyopathy

Protein & Cell ◽

10.1007/s13238-021-00843-w ◽

2021 ◽

Author(s):

Bin Li ◽

Yongkun Zhan ◽

Qianqian Liang ◽

Chen Xu ◽

Xinyan Zhou ◽

...

Keyword(s):

Stem Cell ◽

Dilated Cardiomyopathy ◽

Pluripotent Stem Cell ◽

Disease Models ◽

Human Pluripotent Stem Cell ◽

Cell Disease ◽

Familial Dilated Cardiomyopathy

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Untangling the Biology of Genetic Cardiomyopathies with Pluripotent Stem Cell Disease Models

Current Cardiology Reports ◽

10.1007/s11886-017-0842-1 ◽

2017 ◽

Vol 19 (4) ◽

Author(s):

Jan W. Buikema ◽

Sean M. Wu

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Disease Models ◽

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A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models

BMC Genomics ◽

10.1186/1471-2164-14-773 ◽

2013 ◽

Vol 14 (1) ◽

pp. 773 ◽

Author(s):

Stefan Frank ◽

Boris V Skryabin ◽

Boris Greber

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Disease Models ◽

Human Pluripotent Stem Cell ◽

Knock Out ◽

Stem Cell Lines

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Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Journal of Visualized Experiments ◽

10.3791/59241 ◽

2019 ◽

Author(s):

Lidia Tagliafierro ◽

Ekaterina Ilich ◽

Malik Moncalvo ◽

Jeffrey Gu ◽

Ahila Sriskanda ◽

...

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Lentiviral Vector ◽

Induced Pluripotent Stem Cell ◽

Disease Models ◽

Epigenome Editing ◽

Efficient Delivery ◽

Induced Pluripotent

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Neurodegenerative disease-specific induced pluripotent stem cell research

Experimental Cell Research ◽

10.1016/j.yexcr.2010.04.022 ◽

2010 ◽

Vol 316 (16) ◽

pp. 2560-2564 ◽

Author(s):

Haruhisa Inoue

Keyword(s):

Stem Cell ◽

Neurodegenerative Disease ◽

Stem Cell Research ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Induced Pluripotent ◽

Disease Specific

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Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models

Expert Opinion on Drug Safety ◽

10.1517/14740338.2012.639358 ◽

2011 ◽

Vol 11 (2) ◽

pp. 285-298 ◽

Author(s):

Udo Kraushaar ◽

Thomas Meyer ◽

Dietmar Hess ◽

Lior Gepstein ◽

Christine L Mummery ◽

...

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Disease Models ◽

Channel Block ◽

Related Gene ◽

Cardiac Safety ◽

Safety Pharmacology ◽

Induced Pluripotent

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Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform

Future Medicinal Chemistry ◽

10.4155/fmc-2018-0520 ◽

2019 ◽

Vol 11 (11) ◽

pp. 1305-1322 ◽

Author(s):

Juan Antonio Garcia-Leon ◽

Javier Vitorica ◽

Antonia Gutierrez

Keyword(s):

Stem Cell ◽

Neurodegenerative Disease ◽

Drug Screening ◽

Pluripotent Stem Cell ◽

Disease Modeling ◽

Human Pluripotent Stem Cell ◽

Screening Platform

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Neurodegenerative disease-specific induced pluripotent stem cell research

Rinsho Shinkeigaku ◽

10.5692/clinicalneurol.51.1078 ◽

2011 ◽

Vol 51 (11) ◽

pp. 1078-1078

Author(s):

Haruhisa Inoue

Keyword(s):

Stem Cell ◽

Neurodegenerative Disease ◽

Stem Cell Research ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Induced Pluripotent ◽

Disease Specific

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Reverse engineering human neurodegenerative disease using pluripotent stem cell technology

Brain Research ◽

10.1016/j.brainres.2015.09.023 ◽

2016 ◽

Vol 1638 ◽

pp. 30-41 ◽

Author(s):

Ying Liu ◽

Wenbin Deng

Keyword(s):

Stem Cell ◽

Reverse Engineering ◽

Neurodegenerative Disease ◽

Pluripotent Stem Cell ◽

Stem Cell Technology ◽

Cell Technology ◽

Human Neurodegenerative Disease

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Therapeutic Applications of Induced Pluripotent Stem Cell Use in Parkinson’s Disease Models

Georgetown Medical Review ◽

10.52504/001c.29784 ◽

2021 ◽

Author(s):

Kahlo Baniadam ◽

Stephen Tranchina ◽

Mary-Kate Lawlor ◽

Juyeon Kakazu

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Stem Cell ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Disease Models ◽

Therapeutic Applications ◽

Induced Pluripotent

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