scholarly journals Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer

Oncogene ◽  
2017 ◽  
Vol 36 (46) ◽  
pp. 6446-6461 ◽  
Author(s):  
K Heilmann ◽  
R Toth ◽  
C Bossmann ◽  
K Klimo ◽  
C Plass ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Methylation ◽  
Human Breast Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Human Breast ◽  
Prognostic Relevance ◽  
Genome Wide

scholarly journals m6A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Dongwen Rong ◽  
Qian Dong ◽  
Huajun Qu ◽  
Xinna Deng ◽  
Fei Gao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Progression ◽  
Human Breast Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Human Breast ◽  
Transcript Stability ◽  
Rna Transcript ◽  
Insight Into ◽  
Competitive Endogenous Rna

AbstractIncreasing evidence demonstrates that long noncoding RNAs (lncRNAs) play critical roles in human breast cancer (BC) tumorigenesis. However, the mechanisms by which lncRNA and N6-methyladenosine (m6A) regulate BC tumorigenesis are still unclear. In the present research, LINC00958 was markedly overexpressed in BC tissue and cells, and LINC00958 upregulation promoted the tumor progression of BC cells. Mechanistically, m6A methyltransferase-like 3 (METTL3) gave rise to the upregulation of LINC00958 by promoting its RNA transcript stability. Moreover, LINC00958 acted as a competitive endogenous RNA for miR-378a-3p to promote YY1. Overall, these data provide novel insight into how m6A-mediated LINC00958 regulates BC tumorigenesis.

scholarly journals Long noncoding RNAs in regulation of human breast cancer: Table 1

2015 ◽  
Vol 15 (3) ◽  
pp. 222-226 ◽  
Author(s):  
Guangxue Wang ◽  
Cuicui Liu ◽  
Shengqiong Deng ◽  
Qian Zhao ◽  
Tieyan Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Human Breast

scholarly journals Regulation of DNA Methylation in Human Breast Cancer

2002 ◽  
Vol 277 (44) ◽  
pp. 41571-41579 ◽  
Author(s):  
Yongjing Guo ◽  
Pouya Pakneshan ◽  
Julienne Gladu ◽  
Andrew Slack ◽  
Moshe Szyf ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Methylation ◽  
Human Breast Cancer ◽  
Human Breast

Prognostic relevance of plasminogen activator u-PA in human breast cancer

1993 ◽  
Vol 29 ◽  
pp. S63
Author(s):  
R. Ferrer ◽  
I. Marugan ◽  
A. lluch ◽  
I. Benet ◽  
J. Garcia-Conde
Keyword(s):  
Breast Cancer ◽  
Plasminogen Activator ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Prognostic Relevance
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