Usefulness of the blood pressure classification in the new 2017 ACC/AHA hypertension guidelines for the prediction of new-onset chronic kidney disease

2019 ◽  
Vol 33 (12) ◽  
pp. 873-878 ◽  
Author(s):  
Toshiki Maeda ◽  
Chikara Yoshimura ◽  
Koji Takahashi ◽  
Kenji Ito ◽  
Tetsuhiko Yasuno ◽  
...  
2020 ◽  
Author(s):  
Pantelis Sarafidis ◽  
Charalampos Loutradis ◽  
Alberto Ortiz ◽  
Luis M Ruilope

Abstract Recent American and European hypertension guidelines are not in agreement regarding blood pressure (BP) targets for persons with chronic kidney disease (CKD). Previous analyses from the African American Study on Kidney Disease (AASK) and Modification of Diet in Renal Disease (MDRD) trials suggested that strict BP control confers nephroprotection for patients with proteinuria, but a mortality benefit was not apparent. In contrast, an analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) subpopulation of CKD patients showed a mortality benefit with the systolic blood pressure (SBP) <120 mmHg versus the SBP <140 target. A recent analysis of the combined MDRD and AASK cohorts supports previous evidence on nephroprotection but also findings from the SPRINT trial on all-cause mortality benefits of intensive versus usual BP control in individuals with CKD.


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