scholarly journals Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Danfei Liu ◽  
Tongyue Zhang ◽  
Xiaoping Chen ◽  
Bixiang Zhang ◽  
Yijun Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Carcinoma Metastasis

LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing

Oncogene ◽  
2021 ◽  
Author(s):  
Yang-Hsiang Lin ◽  
Meng-Han Wu ◽  
Yi-Chung Liu ◽  
Ping-Chiang Lyu ◽  
Chau-Ting Yeh ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mrna Splicing ◽  
Carcinoma Metastasis

Tumor cells derived-extracellular vesicles transfer miR-3129 to promote hepatocellular carcinoma metastasis by targeting TXNIP

2021 ◽  
Vol 53 (4) ◽  
pp. 474-485
Author(s):  
Yang Yang ◽  
Feifei Mao ◽  
Lei Guo ◽  
Jie Shi ◽  
Mengchao Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Cells ◽  
Extracellular Vesicles ◽  
Carcinoma Metastasis

Research on Mechanism of miRNA-22 Related with Hepatocellular Carcinoma Metastasis for Regulating Process of Tumor Protein P53

2021 ◽  
Vol 11 (11) ◽  
pp. 2115-2119
Author(s):  
Gang Pan ◽  
Min Xiao
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Invasion ◽  
Cell Activity ◽  
Rt Pcr ◽  
Transwell Assay ◽  
Hep2 Cell ◽  
Tumor Protein P53 ◽  
Carcinoma Metastasis ◽  
Invasion Capacity ◽  
P53 Mrna

The action of miRNA-22 related with HCC metastasis was analyzed in our study and the mechanism of miRNA-22 related with HCC metastasis was discussed. The HCC hep2 cell was transfected with miRNA-22 mimics and miRNA-22 NC instantaneously followed by analysis of cell migration by Transwell assay, cell viability by MTT and clone formation and cell apoptosis by flow cytometry. The action of miRNA-22 mimics and miRNA-22 on the expression of P53 mRNA in HCC Hep2 cell was detected by RT-PCR. The cell activity in miRNA-22 mimics group was significantly elevated compared with miRNA-22 NC group (P < 0.01). Meanwhile, the apoptotic rate, migrated and invaded capacity of HCC cell was significantly elevated (P < 0.01). The expression level of P53 mRNA was reduced (P < 0.01). In conclusion, overexpression of miRNA-22 could restrain the apoptosis of HCC hep2 cell and down-regulated the expression of P53 so as to prompt cell invasion capacity.

Tiam1 is associated with hepatocellular carcinoma metastasis

2012 ◽  
Vol 132 (1) ◽  
pp. 90-100 ◽  
Author(s):  
Jing Huang ◽  
Xianghua Ye ◽  
Jian Guan ◽  
Bin Chen ◽  
Qisheng Li ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Carcinoma Metastasis
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