Targeted 25-hydroxyvitamin D concentration measurements and vitamin D3 supplementation can have important patient and public health benefits

Vitamin D deficiency is a condition often found in various autoimmune diseases, including vitiligo. There were clinical improvements in autoimmune patients who had been given oral vitamin D supplementation, as well as vitiligo patients. This study aimed to analyze the comparison effect of a combination therapy of 308-nmexcimer light phototherapy and vitamin D3 supplementation toward 308-nm-excimer light phototherapy alone to increase of serum 25-(OH)D levels in childhood vitiligo patients. Subjects consisted of 16 childhood vitiligo patients that divided into two groups; group I was given a combination of 308-nm-excimer light phototherapy and 5000 IU of vitamin D3 supplement once daily, while group II was given monotherapy of excimer light. There were highly significant increase of 25-(OH)D serum in both groups which were 324.00±119.066% and 29.84±36.106%, respectively. The very significant result was seen in a comparison of average increased of serum 25-(OH)D levels between both groups. The study concluded that combination of 308-nm-excimer light phototherapy and vitamin D3 supplementation gave a better effect than phototherapy only to increase of serum 25- (OH)D levels in childhood vitiligo patients.

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Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis

SciVee ◽

10.4016/48110.01 ◽

2012 ◽

Cited By ~ 1

Author(s):

Laura Tripkovic ◽

Helen Lambert ◽

Kathryn Hart ◽

Colin Smith ◽

Giselda Bucca ◽

...

Keyword(s):

Systematic Review ◽

Vitamin D3 ◽

Meta Analysis ◽

Vitamin D2 ◽

Hydroxyvitamin D ◽

Vitamin D3 Supplementation ◽

25 Hydroxyvitamin D

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Effects of vitamin D supplementation on depression in patients with colorectal cancer

10.21203/rs.2.22782/v1 ◽

2020 ◽

Author(s):

JianWen Duan ◽

YongSheng Chen ◽

WenFei Wu ◽

Cong Xiong ◽

ZuLiang Hu ◽

...

Keyword(s):

Colorectal Cancer ◽

Vitamin D ◽

Vitamin D3 ◽

Rating Scale ◽

Vitamin D Supplementation ◽

Hydroxyvitamin D ◽

Vitamin D3 Supplementation ◽

Healthy Control ◽

25 Hydroxyvitamin D ◽

Vitamin D 3

Abstract Background: The relation and possible mechnism of vitamin D supplementation on depression in colorectal cancer (CRC) patients was not clearly ; Objective: This study investigates the effect of vitamin D supplementation on depression in colorectal cancer (CRC) patients. Methods : We recruited 168 CRC patients and 168 healthy control subjects into this study. 17-item Hamilton Depression Rating Scale (HDRS-17) was used to assess depression. Results: We found that 25-hydroxyvitamin D (25(OH)D) concentrations were independently associated with depression among CRC patients. For the 45 depressed patients receiving vitamin D3 supplementation, depression scores decreased markedly with 25(OH)D concentrations increasing to normal. Conclusion: Therefore, we advise monitoring this indicator in CRC patients and supplementing with vitamin D 3 when their 25(OH)D concentrations are low.

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