Eplerenone levels in maternal serum, cord blood, and breast milk during pregnancy and lactation

Author(s):  
Jumpei Saito ◽  
Asako Mito ◽  
Naho Yakuwa ◽  
Kayoko Kaneko ◽  
Hiroyo Kawasaki ◽  
...  
Rheumatology ◽  
2019 ◽  
Vol 58 (8) ◽  
pp. 1505-1507 ◽  
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Jumpei Saito ◽  
Naho Yakuwa ◽  
Kayoko Kaneko ◽  
Chinatsu Takai ◽  
Mikako Goto ◽  
...  

2021 ◽  
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Jumpei Saito ◽  
Mariko Ishii ◽  
Yoriko Miura ◽  
Naho Yakuwa ◽  
Hiroyo Kawasaki ◽  
...  

2020 ◽  
Vol 15 (12) ◽  
pp. 809-812
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Naho Yakuwa ◽  
Aiko Sasaki ◽  
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Tomo Suzuki ◽  
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2020 ◽  
Vol 15 (9) ◽  
pp. 598-601
Author(s):  
Jumpei Saito ◽  
Naho Yakuwa ◽  
Noriko Sandaiji ◽  
Hiroyo Kawasaki ◽  
Kayoko Kaneko ◽  
...  

Author(s):  
Jumpei Saito ◽  
Mariko Ishii ◽  
Asako Mito ◽  
Naho Yakuwa ◽  
Hiroyo Kawasaki ◽  
...  

2021 ◽  
Author(s):  
Jumpei Saito ◽  
Mariko Ishii ◽  
Asako Mito ◽  
Naho Yakuwa ◽  
Hiroyo Kawasaki ◽  
...  

2018 ◽  
Vol 13 (2) ◽  
pp. 267-269 ◽  
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Entcho Klenske ◽  
Lourdes Osaba ◽  
Daniel Nagore ◽  
Timo Rath ◽  
Markus F Neurath ◽  
...  

DICP ◽  
1989 ◽  
Vol 23 (1) ◽  
pp. 56-57 ◽  
Author(s):  
Allan J. Ellsworth ◽  
John R. Horn ◽  
Vidmantas A. Raisys ◽  
Lea Ann Miyagawa ◽  
Judy L. Bell

Maternal serum and breast milk were obtained to determine the concentration of disopyramide (DP) and its metabolite N-monodesalkyl disopyramide (NMD) from a woman requiring antidysrhythmic drug therapy. Infant serum and urine were also obtained for drug concentrations. DP 450 mg tid resulted in peak maternal serum concentrations of 4.0 μg/mL and 2.2 μg/mL for DP and NMD, respectively. Breast milk concentrations averaged 1.06 and 6.24 times the serum levels for DP and NMD, respectively. No DP was measurable in the infant's serum except for cord blood, which contained 0.7 μg/mL DP, 26 percent of simultaneous maternal concentration, and 0.9 μg/mL NMD, which represented 43 percent of the maternal concentration. Infant urine collected over an eight-hour period contained 3.3 μg/mL of DP and 3.7 μg/mL of NMD.


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