scholarly journals The role of forelimb motor cortex areas in goal directed action in mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Karin Morandell ◽  
Daniel Huber
Keyword(s):  
Motor Cortex ◽  
Directed Action

scholarly journals Pre-motor versus motor cerebral cortex neuromodulation for chronic neuropathic pain

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Igor Lavrov ◽  
Timur Latypov ◽  
Elvira Mukhametova ◽  
Brian Lundstrom ◽  
Paola Sandroni ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cerebral Cortex ◽  
Motor Cortex ◽  
Initial Assessment ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect ◽  
Stimulation Of

AbstractElectrical stimulation of the cerebral cortex (ESCC) has been used to treat intractable neuropathic pain for nearly two decades, however, no standardized approach for this technique has been developed. In order to optimize targeting and validate the effect of ESCC before placing the permanent grid, we introduced initial assessment with trial stimulation, using a temporary grid of subdural electrodes. In this retrospective study we evaluate the role of electrode location on cerebral cortex in control of neuropathic pain and the role of trial stimulation in target-optimization for ESCC. Location of the temporary grid electrodes and location of permanent electrodes were evaluated in correlation with the long-term efficacy of ESCC. The results of this study demonstrate that the long-term effect of subdural pre-motor cortex stimulation is at least the same or higher compare to effect of subdural motor or combined pre-motor and motor cortex stimulation. These results also demonstrate that the initial trial stimulation helps to optimize permanent electrode positions in relation to the optimal functional target that is critical in cases when brain shift is expected. Proposed methodology and novel results open a new direction for development of neuromodulation techniques to control chronic neuropathic pain.

scholarly journals Role of cutaneous and proprioceptive inputs in sensorimotor integration and plasticity occurring in the facial primary motor cortex

2020 ◽  
Vol 598 (4) ◽  
pp. 839-851 ◽  
Author(s):  
Giovanna Pilurzi ◽  
Francesca Ginatempo ◽  
Beniamina Mercante ◽  
Luigi Cattaneo ◽  
Giovanni Pavesi ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Sensorimotor Integration ◽  
Primary Motor Cortex ◽  
Proprioceptive Inputs

scholarly journals The Role of the Contralesional Motor Cortex for Motor Recovery in the Early Days after Stroke Assessed with Longitudinal fMRI

2010 ◽  
Vol 21 (4) ◽  
pp. 756-768 ◽  
Author(s):  
Anne K. Rehme ◽  
Gereon R. Fink ◽  
D. Yves von Cramon ◽  
Christian Grefkes
Keyword(s):  
Motor Cortex ◽  
Motor Recovery

scholarly journals A comparison of the role of the motor cortex in recovery from cerebellar damage in young and adult rats

1974 ◽  
Vol 12 (2) ◽  
pp. 177-198 ◽  
Author(s):  
Rebekah L. Smith ◽  
Thomas Parks ◽  
Gary Lynch
Keyword(s):  
Motor Cortex ◽  
Adult Rats ◽  
Cerebellar Damage

Role of Voluntary Drive in Encoding an Elementary Motor Memory

2005 ◽  
Vol 93 (2) ◽  
pp. 1099-1103 ◽  
Author(s):  
Alain Kaelin-Lang ◽  
Lumy Sawaki ◽  
Leonardo G. Cohen
Keyword(s):  
Motor Cortex ◽  
Primary Motor Cortex ◽  
Motor Memory ◽  
Motor Drive ◽  
Motor Training ◽  
Corticomotor Excitability ◽  
Proprioceptive Input ◽  
Active Training ◽  
Passive Movements

Motor training consisting of repetitive thumb movements results in encoding of motor memories in the primary motor cortex. It is not known if proprioceptive input originating in the training movements is sufficient to produce this effect. In this study, we compared the ability of training consisting of voluntary (active) and passively-elicited (passive) movements to induce this form of plasticity. Active training led to successful encoding accompanied by characteristic changes in corticomotor excitability, while passive training did not. These results support a pivotal role for voluntary motor drive in coding motor memories in the primary motor cortex.

scholarly journals Carbohydrate Mouth Rinse Mitigates Mental Fatigue Effects on Maximal Incremental Test Performance, but Not in Cortical Alterations

2020 ◽  
Vol 10 (8) ◽  
pp. 493 ◽  
Author(s):  
Cayque Brietzke ◽  
Paulo Estevão Franco-Alvarenga ◽  
Raul Canestri ◽  
Márcio Fagundes Goethel ◽  
Ítalo Vínicius ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Exercise Performance ◽  
Test Performance ◽  
Time Trial ◽  
Mental Fatigue ◽  
Mouth Rinse ◽  
Incremental Test ◽  
Mouth Rinses ◽  
Spontaneous Behavior

Detrimental mental fatigue effects on exercise performance have been documented in constant workload and time trial exercises, but effects on a maximal incremental test (MIT) remain poorly investigated. Mental fatigue-reduced exercise performance is related to an increased effort sensation, likely due to a reduced prefrontal cortex (PFC) activation and inhibited spontaneous behavior. Interestingly, only a few studies verified if centrally active compounds may mitigate such effects. For example, carbohydrate (CHO) mouth rinse potentiates exercise performance and reduces effort sensation, likely through its effects on PFC activation. However, it is unknown if this centrally mediated effect of CHO mouth rinse may mitigate mental fatigue-reduced exercise performance. After a proof-of-principle study, showing a mental fatigue-reduced MIT performance, we observed that CHO mouth rinse mitigated MIT performance reductions in mentally fatigued cyclists, regardless of PFC alterations. When compared to placebo, mentally fatigued cyclists improved MIT performance by 2.24–2.33% when rinsing their mouth with CHO during MIT. However, PFC and motor cortex activation during MIT in both CHO and placebo mouth rinses were greater than in mental fatigue. Results showed that CHO mouth rinse mitigated the mental fatigue-reduced MIT performance, but challenged the role of CHO mouth rinse on PFC and motor cortex activation.

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