scholarly journals Long-term cyclic use of a sample collector for toilet-based urine analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mikail Temirel ◽  
Bekir Yenilmez ◽  
Savas Tasoglu
Keyword(s):  
Health Monitoring ◽  
Urine Analysis ◽  
Geometric Parameters ◽  
Design Parameters ◽  
Sample Collection ◽  
3D Printed ◽  
Continuous Health Monitoring

AbstractUrine analysis via a toilet-based device can enable continuous health monitoring, a transformation away from hospital-based care towards more proactive medicine. To enable reliable sample collection for a toilet-attached analyzer, here a novel sample collector is proposed. The applicability of the proposed sample collector is validated for long-term use. Geometric parameters of the 3D-printed sample collector are optimized. The collected and leftover volumes are quantified for a range of urination speeds and design parameters. For long-term cyclic use, the protein concentrations of samples are quantified and the effectiveness of washing the sample collector is assessed.

Investigation of future 3D printed brace design parameters: evaluation of mechanical properties and prototype outcomes

2019 ◽  
Vol 3 (4) ◽  
pp. 171-184
Author(s):  
Kenwick JL Ng ◽  
Kajsa Duke ◽  
Edmond Lou
Keyword(s):  
Mechanical Properties ◽  
Mechanical Characteristics ◽  
Treatment Effectiveness ◽  
Design Parameters ◽  
Wear Comfort ◽  
Polypropylene Material ◽  
Spinal Brace ◽  
3D Printed ◽  
Opening And Closing

Aim: Spinal brace wear time affects treatment effectiveness of adolescent idiopathic scoliosis but remains challenging with the brace’s bulkiness. This study aims to determine the appropriate material and thickness to improve wear comfort. Materials & methods: Thirty-one specimens were tested with 13 ULTEM1010 and 13 Nylon12 potential materials and 5 standard polypropylene material in 2.5, 3.25 and 4 mm thicknesses to evaluate mechanical properties. Donning tests of ULTEM1010 and Nylon12 printed braces were conducted. Results: Nylon12 with 2.5–3.25 mm thickness had higher flexibility and the closest mechanical characteristics as 4-mm thick polypropylene. ULTEM1010 brace fractured after 615-times and Nylon12 brace handled 2920-times of opening and closing. Conclusion: Nylon12, 2.5–3.25 mm are appropriate design parameters. Further clinical study can validate long term brace effectiveness.

Effective optimization of SARS-CoV-2 laboratory testing variables in an era of supply chain constraints

2020 ◽  
Vol 15 (15) ◽  
pp. 1483-1487
Author(s):  
Nikhil S Sahajpal ◽  
Ashis K Mondal ◽  
Allan Njau ◽  
Sudha Ananth ◽  
Kimya Jones ◽  
...  
Keyword(s):  
Supply Chain ◽  
Rna Extraction ◽  
Nasopharyngeal Swab ◽  
Sample Collection ◽  
Rt Pcr ◽  
Pcr Assay ◽  
Short Supply ◽  
Viral Transport ◽  
3D Printed ◽  
Bridging Studies

RT-PCR-based assays for the detection of SARS-CoV-2 have played an essential role in the current COVID-19 pandemic. However, the sample collection and test reagents are in short supply, primarily due to supply chain issues. Thus, to eliminate testing constraints, we have optimized three key process variables: RNA extraction and RT-PCR reactions, different sample types and media to facilitate SARS-CoV-2 testing. By performing various validation and bridging studies, we have shown that various sample types such as nasopharyngeal swab, bronchioalveolar lavage and saliva, collected using conventional nasopharyngeal swabs, ESwab or 3D-printed swabs and, preserved in viral transport media, universal transport media, 0.9% sodium chloride or Amies media are compatible with RT-PCR assay for COVID-19. Besides, the reduction of PCR reagents by up to fourfold also produces reliable results.

scholarly journals A Novel Approach for a Faster Prototyping of Winter Sport Equipment Using Digital Image Correlation and 3D Printing

Proceedings ◽  
2020 ◽  
Vol 49 (1) ◽  
pp. 125
Author(s):  
Martino Colonna ◽  
Benno Zingerle ◽  
Maria Federica Parisi ◽  
Claudio Gioia ◽  
Alessandro Speranzoni ◽  
...  
Keyword(s):  
3D Printing ◽  
Digital Image Correlation ◽  
Digital Image ◽  
Sport Activity ◽  
Image Correlation ◽  
Topological Optimization ◽  
Design Parameters ◽  
Sport Equipment ◽  
Novel Approach ◽  
3D Printed

The optimization of sport equipment parts requires considerable time and high costs due to the high complexity of the development process. For this reason, we have developed a novel approach to decrease the cost and time for the optimization of the design, which consists of producing a first prototype by 3D printing, applying the forces that normally acts during the sport activity using a test bench, and then measuring the local deformations using 3D digital image correlation (DIC). The design parameters are then modified by topological optimization and then DIC is performed again on the new 3D-printed modified part. The DIC analysis of 3D-printed parts has shown a good agreement with that of the injection-molded ones. The deformation measured with DIC are also well correlated with those provided by finite element method (FEM) analysis, and therefore DIC analysis proves to be a powerful tool to validate FEM models.

scholarly journals Long-Term IoT-Based Maternal Monitoring: System Design and Evaluation

Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2281
Author(s):  
Fatemeh Sarhaddi ◽  
Iman Azimi ◽  
Sina Labbaf ◽  
Hannakaisa Niela-Vilén ◽  
Nikil Dutt ◽  
...  
Keyword(s):  
Energy Efficiency ◽  
Maternal Health ◽  
Pregnant Women ◽  
Health Monitoring ◽  
Quality Care ◽  
Well Being ◽  
Pregnancy And Postpartum ◽  
Comprehensive Framework ◽  
Specific Health

Pregnancy is a unique time when many mothers gain awareness of their lifestyle and its impacts on the fetus. High-quality care during pregnancy is needed to identify possible complications early and ensure the mother’s and her unborn baby’s health and well-being. Different studies have thus far proposed maternal health monitoring systems. However, they are designed for a specific health problem or are limited to questionnaires and short-term data collection methods. Moreover, the requirements and challenges have not been evaluated in long-term studies. Maternal health necessitates a comprehensive framework enabling continuous monitoring of pregnant women. In this paper, we present an Internet-of-Things (IoT)-based system to provide ubiquitous maternal health monitoring during pregnancy and postpartum. The system consists of various data collectors to track the mother’s condition, including stress, sleep, and physical activity. We carried out the full system implementation and conducted a real human subject study on pregnant women in Southwestern Finland. We then evaluated the system’s feasibility, energy efficiency, and data reliability. Our results show that the implemented system is feasible in terms of system usage during nine months. We also indicate the smartwatch, used in our study, has acceptable energy efficiency in long-term monitoring and is able to collect reliable photoplethysmography data. Finally, we discuss the integration of the presented system with the current healthcare system.

scholarly journals Effect of Geometric Parameters and Moisture Content on the Mechanical Performances of 3D-Printed Isogrid Structures in Short Carbon Fiber-Reinforced Polyamide

2021 ◽  
Author(s):  
Valerio Di Pompeo ◽  
Archimede Forcellese ◽  
Tommaso Mancia ◽  
Michela Simoncini ◽  
Alessio Vita
Keyword(s):  
Carbon Fiber ◽  
Moisture Content ◽  
Geometric Parameters ◽  
Fiber Reinforced ◽  
Compression Tests ◽  
Short Carbon Fiber ◽  
3D Printed ◽  
Carbon Fiber Reinforced ◽  
Mechanical Performances ◽  
Short Carbon

AbstractThe present paper aims at studying the effect of geometric parameters and moisture content on the mechanical performances of 3D-printed isogrid structures in short carbon fiber-reinforced polyamide (namely Carbon PA). Four different geometric isogrid configurations were manufactured, both in the undried and dried condition. The dried isogrid structures were obtained by removing the moisture from the samples through a heating at 120 °C for 4 h. To measure the quantity of removed moisture, samples were weighted before and after the drying process. Tensile tests on standard specimens and buckling tests on isogrid panels were performed. Undried samples were tested immediately after 3D printing. It was observed that the dried samples are characterized by both Young modulus and ultimate tensile strength values higher than those provided by the undried samples. Similar results were obtained by the compression tests since, for a given geometric isogrid configuration, an increase in the maximum load of the dried structure was detected as compared to the undried one. Such discrepancy tends to increase as the structure with the lowest thickness value investigated is considered. Finally, scanning electron microscopy was carried out in order to analyze the fractured samples and to obtain high magnification three-dimensional topography of fractured surfaces after testing.

scholarly journals A millifluidic chip for cultivation of fish embryos and toxicity testing fabricated by 3D printing technology

RSC Advances ◽  
2021 ◽  
Vol 11 (33) ◽  
pp. 20507-20518
Author(s):  
Petr Panuška ◽  
Zuzana Nejedlá ◽  
Jiří Smejkal ◽  
Petr Aubrecht ◽  
Michaela Liegertová ◽  
...  
Keyword(s):  
3D Printing ◽  
Toxicity Testing ◽  
Toxicity Screening ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Fish Embryos ◽  
3D Printed ◽  
Novel Design

A novel design of 3D printed zebrafish millifluidic system for embryonic long-term cultivation and toxicity screening has been developed. The chip unit provides 24 cultivation chambers and a selective individual embryo removal functionality.

scholarly journals Recurrent contracted sockets treated with personalized, three-dimensionally printed conformers and buccal grafts

2021 ◽  
pp. 112067212110000
Author(s):  
Annabel LW Groot ◽  
Jelmer S Remmers ◽  
Roel JHM Kloos ◽  
Peerooz Saeed ◽  
Dyonne T Hartong
Keyword(s):  
Three Dimensional ◽  
Case Series ◽  
Secondary Outcome ◽  
Retrospective Case ◽  
Upper Eyelid ◽  
Ocular Prosthesis ◽  
Buccal Mucosal Graft ◽  
Custom Made ◽  
3D Printed

Purpose: Recurrent contracted sockets are complex situations where previous surgeries have failed, disabling the wear of an ocular prosthesis. A combined method of surgery and long-term fixation using custom-made, three-dimensional (3D) printed conformers is evaluated. Methods: Retrospective case series of nine patients with recurrent excessive socket contraction and inability to wear a prosthesis, caused by chemical burns ( n = 3), fireworks ( n = 3), trauma ( n = 2) and enucleation and radiotherapy at childhood due to optic nerve glioma ( n = 1) with three average previous socket surgeries (range 2–6). Treatment consisted of a buccal mucosal graft and personalized 3D-printed conformer designed to be fixated to the periosteum and tarsal plates for minimal 2 months. Primary outcome was the retention of an ocular prosthesis. Secondary outcome was the need for additional surgeries. Results: Outcomes were measured at final follow-up between 7 and 36 months postoperatively (mean 20 months). Eight cases were able to wear an ocular prosthesis after 2 months. Three cases initially treated for only the upper or only the lower fornix needed subsequent surgery for the opposite fornix for functional reasons. Two cases had later surgery for cosmetic improvement of upper eyelid position. Despite pre-existing lid abnormalities (scar, entropion, lash deficiency), cosmetic outcome was judged highly acceptable in six cases because of symmetric contour and volume, and reasonably acceptable in the remaining two. Conclusions: Buccal mucosal transplant fixated with a personalized 3D-designed conformer enables retention of a well-fitted ocular prosthesis in previously failed socket surgeries. Initial treatment of both upper and lower fornices is recommended to avoid subsequent surgeries for functional reasons.

Dry Flexible Electrode Based on MWCNT for Long Term Health Monitoring

2021 ◽  
Author(s):  
Chiraz Naggara ◽  
Dhouha Bouchaala ◽  
Rajarajan Ramalingame ◽  
Nabil Derbel ◽  
Olfa Kanoun
Keyword(s):  
Health Monitoring ◽  
Flexible Electrode
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