Epidermal growth factor receptor (EGFR); heat shock protein 90 (Hsp90)

Science-Business eXchange ◽

10.1038/scibx.2013.920 ◽

2013 ◽

Vol 6 (34) ◽

pp. 920-920

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Epidermal Growth

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Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers

Cancer Science ◽

10.1111/j.1349-7006.2011.02144.x ◽

2011 ◽

Vol 103 (2) ◽

pp. 342-349 ◽

Author(s):

Naomi Ono ◽

Toshikazu Yamazaki ◽

Yoshito Nakanishi ◽

Toshihiko Fujii ◽

Kiyoaki Sakata ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

The Novel ◽

Epidermal Growth

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Destabilization of the Epidermal Growth Factor Receptor (EGFR) by a Peptide That Inhibits EGFR Binding to Heat Shock Protein 90 and Receptor Dimerization

Journal of Biological Chemistry ◽

10.1074/jbc.m113.492280 ◽

2013 ◽

Vol 288 (37) ◽

pp. 26879-26886 ◽

Author(s):

Aarif Ahsan ◽

Dipankar Ray ◽

Susmita G. Ramanand ◽

Ashok Hegde ◽

Christopher Whitehead ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Receptor Dimerization ◽

Epidermal Growth

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Transactivation of the Epidermal Growth Factor Receptor by Heat Shock Protein 90 via Toll-like Receptor 4 Contributes to the Migration of Glioblastoma Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m110.154823 ◽

2010 ◽

Vol 286 (5) ◽

pp. 3418-3428 ◽

Author(s):

Dominique Thuringer ◽

Arlette Hammann ◽

Naïma Benikhlef ◽

Eric Fourmaux ◽

André Bouchot ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Epidermal Growth

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Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Breast Cancer Research ◽

10.1186/bcr3168 ◽

2012 ◽

Vol 14 (2) ◽

Author(s):

Qing Cheng ◽

Jeffrey T Chang ◽

Joseph Geradts ◽

Leonard M Neckers ◽

Timothy Haystead ◽

...

Keyword(s):

Breast Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

High Level Expression ◽

Epidermal Growth ◽

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Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-08-1038 ◽

2009 ◽

Vol 8 (8) ◽

pp. 2131-2141 ◽

Author(s):

Ching Ching Leow ◽

Jon Chesebrough ◽

Karen T. Coffman ◽

Christine A. Fazenbaker ◽

John Gooya ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Single Agent ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Epidermal Growth ◽

Xenograft Models ◽

Human Xenograft Models

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Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type

Oncology Reports ◽

10.3892/or.2017.5863 ◽

2017 ◽

Vol 38 (4) ◽

pp. 2394-2400 ◽

Author(s):

Elsa Sartori ◽

Rupert Langer ◽

Erik Vassella ◽

Ekkehard Hewer ◽

Philippe Schucht ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Wild Type ◽

Primary Glioblastoma ◽

Epidermal Growth ◽

Worse Prognosis

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Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

Oncogene ◽

10.1038/onc.2010.277 ◽

2010 ◽

Vol 29 (37) ◽

pp. 5204-5213 ◽

Author(s):

L Meng ◽

V L Gabai ◽

M Y Sherman

Keyword(s):

Transcription Factor ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Critical Role ◽

Growth Factor Receptor ◽

Cellular Transformation ◽

Human Epidermal Growth Factor ◽

Epidermal Growth

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Epidermal Growth Factor Receptors Harboring Kinase Domain Mutations Associate with the Heat Shock Protein 90 Chaperone and Are Destabilized following Exposure to Geldanamycins

Cancer Research ◽

10.1158/0008-5472.can-05-0933 ◽

2005 ◽

Vol 65 (14) ◽

pp. 6401-6408 ◽

Author(s):

Takeshi Shimamura ◽

April M. Lowell ◽

Jeffrey A. Engelman ◽

Geoffrey I. Shapiro

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Heat Shock Protein 90 ◽

Growth Factor Receptors ◽

Kinase Domain ◽

Epidermal Growth Factor Receptors ◽

Epidermal Growth ◽

Kinase Domain Mutations

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Abstract P4-14-21: A phase I trial of ganetespib (heat shock protein 90 inhibitor) in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 positive (HER2+) metastatic breast cancer (MBC)

10.1158/1538-7445.sabcs15-p4-14-21 ◽

2016 ◽

Author(s):

K Jhaveri ◽

E Teplinsky ◽

S Chandarlapaty ◽

D Solit ◽

K Cadoo ◽

...

Keyword(s):

Breast Cancer ◽

Epidermal Growth Factor Receptor ◽

Metastatic Breast Cancer ◽

Growth Factor ◽

Phase I Trial ◽

Growth Factor Receptor ◽

Metastatic Breast ◽

Heat Shock Protein 90 ◽

Epidermal Growth

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Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells

FEBS Letters ◽

10.1016/j.febslet.2006.11.024 ◽

2006 ◽

Vol 580 (28-29) ◽

pp. 6674-6678 ◽

Author(s):

Anton L. Evdonin ◽

Irina V. Guzhova ◽

Boris A. Margulis ◽

Natalia D. Medvedeva

Keyword(s):

Epidermal Growth Factor Receptor ◽

Heat Stress ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Heat Shock Protein 70 ◽

Growth Factor Receptor ◽

Carcinoma Cells ◽

Epidermal Growth ◽

Receptor Transactivation

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