Transactivation of the Epidermal Growth Factor Receptor by Heat Shock Protein 90 via Toll-like Receptor 4 Contributes to the Migration of Glioblastoma Cells

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Epidermal growth factor receptor (EGFR); heat shock protein 90 (Hsp90)

Science-Business eXchange ◽

10.1038/scibx.2013.920 ◽

2013 ◽

Vol 6 (34) ◽

pp. 920-920

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers

Cancer Science ◽

10.1111/j.1349-7006.2011.02144.x ◽

2011 ◽

Vol 103 (2) ◽

pp. 342-349 ◽

Cited By ~ 18

Author(s):

Naomi Ono ◽

Toshikazu Yamazaki ◽

Yoshito Nakanishi ◽

Toshihiko Fujii ◽

Kiyoaki Sakata ◽

...

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

The Novel ◽

Destabilization of the Epidermal Growth Factor Receptor (EGFR) by a Peptide That Inhibits EGFR Binding to Heat Shock Protein 90 and Receptor Dimerization

Journal of Biological Chemistry ◽

10.1074/jbc.m113.492280 ◽

2013 ◽

Vol 288 (37) ◽

pp. 26879-26886 ◽

Cited By ~ 23

Author(s):

Aarif Ahsan ◽

Dipankar Ray ◽

Susmita G. Ramanand ◽

Ashok Hegde ◽

Christopher Whitehead ◽

...

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Receptor Dimerization ◽

Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

Mucosal Immunology ◽

10.1038/mi.2015.30 ◽

2015 ◽

Vol 8 (5) ◽

pp. 1166-1179 ◽

Cited By ~ 94

Author(s):

M Good ◽

C P Sodhi ◽

C E Egan ◽

A Afrazi ◽

H Jia ◽

...

Keyword(s):

Growth Factor ◽

Breast Milk ◽

Epidermal Growth Factor ◽

Necrotizing Enterocolitis ◽

Intestinal Epithelium ◽

Growth Factor Receptor ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Breast Cancer Research ◽

10.1186/bcr3168 ◽

2012 ◽

Vol 14 (2) ◽

Cited By ~ 76

Author(s):

Qing Cheng ◽

Jeffrey T Chang ◽

Joseph Geradts ◽

Leonard M Neckers ◽

Timothy Haystead ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

High Level Expression ◽

Epidermal Growth ◽

High Level

Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-08-1038 ◽

2009 ◽

Vol 8 (8) ◽

pp. 2131-2141 ◽

Cited By ~ 32

Author(s):

Ching Ching Leow ◽

Jon Chesebrough ◽

Karen T. Coffman ◽

Christine A. Fazenbaker ◽

John Gooya ◽

...

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Single Agent ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Epidermal Growth ◽

Xenograft Models ◽

Human Xenograft Models

Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type

Oncology Reports ◽

10.3892/or.2017.5863 ◽

2017 ◽

Vol 38 (4) ◽

pp. 2394-2400 ◽

Cited By ~ 4

Author(s):

Elsa Sartori ◽

Rupert Langer ◽

Erik Vassella ◽

Ekkehard Hewer ◽

Philippe Schucht ◽

...

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Heat Shock Protein 90 ◽

Wild Type ◽

Primary Glioblastoma ◽

Epidermal Growth ◽

Worse Prognosis

Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

Oncogene ◽

10.1038/onc.2010.277 ◽

2010 ◽

Vol 29 (37) ◽

pp. 5204-5213 ◽

Cited By ~ 89

Author(s):

L Meng ◽

V L Gabai ◽

M Y Sherman

Keyword(s):

Transcription Factor ◽

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Critical Role ◽

Growth Factor Receptor ◽

Cellular Transformation ◽

Human Epidermal Growth Factor ◽

Epidermal Growth Factor Receptors Harboring Kinase Domain Mutations Associate with the Heat Shock Protein 90 Chaperone and Are Destabilized following Exposure to Geldanamycins

Cancer Research ◽

10.1158/0008-5472.can-05-0933 ◽

2005 ◽

Vol 65 (14) ◽

pp. 6401-6408 ◽

Cited By ~ 181

Author(s):

Takeshi Shimamura ◽

April M. Lowell ◽

Jeffrey A. Engelman ◽

Geoffrey I. Shapiro

Keyword(s):

Growth Factor ◽

Heat Shock ◽

Epidermal Growth Factor ◽

Heat Shock Protein ◽

Heat Shock Protein 90 ◽

Growth Factor Receptors ◽

Kinase Domain ◽

Epidermal Growth Factor Receptors ◽

Epidermal Growth ◽

Kinase Domain Mutations

Pulmonary Proteases in the Cystic Fibrosis Lung Induce Interleukin 8 Expression from Bronchial Epithelial Cells via a Heme/Meprin/Epidermal Growth Factor Receptor/Toll-like Receptor Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m110.183863 ◽

2010 ◽

Vol 286 (9) ◽

pp. 7692-7704 ◽

Cited By ~ 40

Author(s):

Sonya Cosgrove ◽

Sanjay H. Chotirmall ◽

Catherine M. Greene ◽

Noel G. McElvaney

Keyword(s):

Cystic Fibrosis ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Epithelial Cells ◽

Growth Factor Receptor ◽

Interleukin 8 ◽

Toll Like Receptor ◽

Bronchial Epithelial ◽