scholarly journals Vaccination with B16 melanoma cells expressing a secreted form of interleukin-1β induces tumor growth inhibition and an enhanced immunity against the wild-type B16 tumor

2000 ◽  
Vol 7 (10) ◽  
pp. 1365-1374 ◽  
Author(s):  
Olle Björkdahl ◽  
Mikael Dohlsten ◽  
Hans-Olov Sjögren
Keyword(s):  
Tumor Growth ◽  
Growth Inhibition ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
Interleukin 1Β ◽  
Tumor Growth Inhibition ◽  
Wild Type ◽  
B16 Melanoma Cells

Overexpression of Notch ligand Dll1 in B16 melanoma cells leads to reduced tumor growth due to attenuated vascularization

2011 ◽  
Vol 309 (2) ◽  
pp. 220-227 ◽  
Author(s):  
Jian-Ping Zhang ◽  
Hong-Yan Qin ◽  
Li Wang ◽  
Liang Liang ◽  
Xing-Cheng Zhao ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
Notch Ligand ◽  
B16 Melanoma Cells

In vitro and in vivo tumor growth inhibition by a p16-mimicking peptide in p16INK4A-defective, pRb-positive human melanoma cells

2004 ◽  
Vol 202 (3) ◽  
pp. 922-928 ◽  
Author(s):  
Douglas M. Noonan ◽  
Anna Severino ◽  
Monica Morini ◽  
Alessandra Tritarelli ◽  
Lucrezia Manente ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Growth Inhibition ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Tumor Growth Inhibition ◽  
Human Melanoma Cells

scholarly journals Saikosaponin b2 Induces Differentiation without Growth Inhibition in Cultured B16 Melanoma Cells.

1998 ◽  
Vol 23 (5) ◽  
pp. 265-272 ◽  
Author(s):  
Zhi-ping Zong ◽  
Kohzaburo Fujikawa-Yamamoto ◽  
Takahide Ota ◽  
Xin Guan ◽  
Manabu Murakami ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells

scholarly journals The designer cytokine hyper-IL-6 mediates growth inhibition and GM–CSF-dependent rejection of B16 melanoma cells

Oncogene ◽  
2001 ◽  
Vol 20 (8) ◽  
pp. 972-979 ◽  
Author(s):  
Suat Özbek ◽  
Malte Peters ◽  
Kai Breuhahn ◽  
Amrit Mann ◽  
Manfred Blessing ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
Gm Csf ◽  
B16 Melanoma Cells

scholarly journals Elucidation of Melanogenesis-Associated Signaling Pathways Regulated by Argan Press Cake in B16 Melanoma Cells

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2697
Author(s):  
Thouria Bourhim ◽  
Myra O. Villareal ◽  
Chemseddoha Gadhi ◽  
Hiroko Isoda
Keyword(s):  
Signaling Pathways ◽  
Press Cake ◽  
Global Gene Expression ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
Dependent Manner ◽  
Melanin Biosynthesis ◽  
B16 Melanoma Cells ◽  
Pigmentary Disorders ◽  
Argan Oil

The beneficial effect on health of argan oil is recognized worldwide. We have previously reported that the cake that remains after argan oil extraction (argan press-cake or APC) inhibits melanogenesis in B16 melanoma cells in a time-dependent manner without cytotoxicity. In this study, the global gene expression profile of B16 melanoma cells treated with APC extract was determined in order to gain an understanding of the possible mechanisms of action of APC. The results suggest that APC extract inhibits melanin biosynthesis by down-regulating microphthalmia-associated transcription factor (Mitf) and its downstream signaling pathway through JNK signaling activation, and the inhibition of Wnt/β-catenin and cAMP/PKA signaling pathways. APC extract also prevented the transport of melanosomes by down-regulating Rab27a expression. These results suggest that APC may be an important natural skin whitening product and pharmacological agent used for clinical treatment of pigmentary disorders.

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