scholarly journals Intravitreal steroids may facilitate treatment of Eales' disease (idiopathic retinal vasculitis): an interventional case series

Eye ◽  
2006 ◽  
Vol 21 (11) ◽  
pp. 1403-1405 ◽  
Author(s):  
M Ishaq ◽  
A H Feroze ◽  
M Shahid ◽  
M A Baig ◽  
S S Ameen ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Rui Zhang ◽  
Jiang Qian ◽  
Jie Guo ◽  
Yifei Yuan ◽  
Kang Xue ◽  
...  

Purpose. To describe the clinical manifestations and treatment outcomes of syphilitic uveitis in a Chinese population.Methods. This is a retrospective case series of 15 consecutive patients with syphilitic uveitis treated at a uveitis referral center between 2012 and 2015.Results. Fifteen patients were diagnosed with syphilitic uveitis based on positive serological tests. Nine patients were male. Coinfection with human immunodeficiency virus was detected in two patients. Twenty eyes presented with panuveitis and all patients had posterior involvement. The most frequent manifestations were retinal vasculitis and papillitis, while syphilitic posterior placoid chorioretinitis was only found in three eyes. All patients received systemic penicillin therapy according to CDC guidelines. Nine patients were misdiagnosed before presenting to our center and the delay in treatment with penicillin was associated with poor final visual outcomes (P<0.05).Conclusions. In our series, both male and female were almost equally affected and coinfection of syphilis with human immunodeficiency virus was uncommon. All patients in this study had posterior involvement and the most common manifestations were retinal vasculitis and papillitis. Syphilis should be considered as an important differential diagnosis especially for posterior uveitis and panuveitis. Early diagnosis and appropriate treatment are important for visual prognosis.


2009 ◽  
Vol 70 (4) ◽  
pp. 515-517 ◽  
Author(s):  
D. K. Sen ◽  
G. S. Sarin ◽  
B. Ghosh ◽  
N. R. Acharya ◽  
N. Gurha

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Zarei ◽  
Hossein Pesarakli ◽  
Mehdi Yaseri ◽  
Hamed Etesali ◽  
Nazanin Ebrahimiadib

AbstractTo study the correlation of OCT parameters including central subfield macular thickness (CSMT), peripapillary retinal thickness (PRT), and peripapillary retinal nerve fiber layer thickness (PNFLT) with fluorescein angiography (FA) in evaluation of inflammatory activity in Behcet’s retinal vasculitis. In this case-series, concurrent FA and OCT were performed. A scoring system was devised for FA. PNFLT in 3.4-mm-diameter circle as well as PRT in doughnut shaped regions between the 1-mm- and 2.2-mm-diameter and between the 2.2-mm- and 3.45-mm-diameter circles was measured. The correlation of FA and OCT parameters was analyzed. A total of 105 sets of FA from 28 eyes (15 patients) were reviewed. Four (26.6%) were female and mean age was 31.6 ± 8.49 years. Each micron increase in CSMT, PRT2.2, PRT3.45, and PNFLT, caused a rise of 0.018 (95% CI 0.008–0.027, P < 0.001, r = 0.413), 0.053 (95% CI 0.035–0.070, P < 0.001, r = 0.443), 0.086 (95% CI 0.065–0.108, P < 0.001, r = 0.707), and 0.185 (95% CI 0.152–to 0.218, P < 0.001, r = 0.850) unit in FA score, respectively. Parameters having significant correlation with angiographic inflammatory activity, were CSMT, PRT2.2, PRT3.45 and RNFLT. Those with the strongest correlation, PRT3.45 and PNFLT, may be considered as quantitative non-invasive alternatives to FA for monitoring Behcet’s retinal vasculitis.


2018 ◽  
Vol 151 (8) ◽  
pp. 336
Author(s):  
José Luis Callejas Rubio ◽  
José Luis García Serrano ◽  
Norberto Ortego Centeno

2003 ◽  
Vol 36 (5) ◽  
pp. 377-385 ◽  
Author(s):  
Mohanraj Rajesh ◽  
Konerirajapuram N. Sulochana ◽  
Ranganathan Punitham ◽  
Jyotirmay Biswas ◽  
Soundarajan Lakshmi ◽  
...  

1970 ◽  
Vol 1 (1) ◽  
pp. 66-71 ◽  
Author(s):  
JK Shrestha ◽  
D Khadka ◽  
G Lamichhane ◽  
S Khanal

Retinal vasculitis is an idiopathic inflammatory venous occlusion primarily affecting the peripheral retina of otherwise healthy young adults. Eales' disease is recognized as primary vasculitis of unknown etiology occurring in young adults. This article aims at the overall review of the etiopathogenesis, clinical presentations, pathology, management and prognosis of retinal vasculitis. Key words: Retinal vasculitis; Eales' disease DOI: 10.3126/nepjoph.v1i1.3675 Nep J Oph 2009;1(1):66-71


2019 ◽  
Vol 30 (5) ◽  
pp. 874-885 ◽  
Author(s):  
Alexia Bernard ◽  
Pascal Seve ◽  
Amro Abukhashabh ◽  
Chantal Roure-Sobas ◽  
Andre Boibieux ◽  
...  

Background: Clinical presentation of Lyme-associated uveitis is poorly described. We reported here a case series of seven patients with uveitis related to Lyme disease and a review of the literature. Methods: A retrospective study in our university hospital between 1 May 2003 and 31 July 2016 on 1006 uveitis patients and review of Pubmed library. Results: Seven patients (71.4% male, mean age = 53 (38–70)) were diagnosed with a Lyme-associated uveitis. All anatomical types of uveitis were found (four intermediate, three anterior, and three posterior uveitis); most were unilateral (n = 6; 85.7%), one granulomatous and two with synechiae. Peripheral retinal vasculitis was present in four patients. They all had a risk of exposure or extra-ophthalmological symptoms. Antibiotic and steroid treatment was rapidly effective in all patients. Four patients presented recurrences of uveitis, of whom two received a second antibiotic treatment, which is quite common in literature. Persistent or recurrence of symptoms can be explained by three hypotheses: (1) reinfection, (2) relapse of original infection, and (3) autoimmune reaction. Conclusion: Lyme-associated uveitis appears varied. Hyalitis and involvement of the posterior segment and retinal vasculitis seem to be rather frequent. Its prognosis is mainly good, even if inflammation can be resistant or recurring.


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