scholarly journals Incidence and risk factors for retinopathy of prematurity in very low and in extremely low birth weight infants in a unit-based approach in southern Brazil

Eye ◽  
2007 ◽  
Vol 23 (1) ◽  
pp. 25-30 ◽  
Author(s):  
J B Fortes Filho ◽  
G U Eckert ◽  
L Procianoy ◽  
C K Barros ◽  
R S Procianoy
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Extremely Low Birth Weight ◽  
Southern Brazil ◽  
Low Birth Weight Infants

scholarly journals The risk factors and progression of retinopathy of prematurity in extremely low birth weight infants

2021 ◽  
Vol 24 (3) ◽  
pp. 181-186
Author(s):  
Igor I. Dyumin ◽  
Elena A. Balakireva ◽  
Elena A. Yaroshevich ◽  
Aleksey I. Sevostyanov ◽  
Igor V. Nikolaenko
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Premature Babies ◽  
Ectopic Pregnancies

The number of premature babies, including those with extremely low birth weight (ELBW), is steadily growing every year. In surviving ELBW infants, retinopathy of prematurity (ROP) more often develops, which has a more severe course, depending not only on the degree of immaturity and somatic burden of premature babies but also on the quality of nursing. The aim of this work is to determine the risk factors for ROP progression in profoundly premature ELBW infants to optimize the tactics of their treatment. Materials and methods. We studied the case histories of 155 surviving premature ELBW infants with ROP of various stages treated in perinatal centres of the Belgorod region in 2014-2019. Results. In premature ELBW infants, ROP of varying severity was found to be diagnosed in 90% of cases. The anamnesis of the mothers of the examined patients with moderate and severe ROP was dominated by unfavorable preceding pregnancies (miscarriages, silent miscarriage and ectopic pregnancies, medical abortions).The need for preterm infants in mechanical ventilation was established to depend on the severity of ROP and the duration of mechanical ventilation (p < 0.05). Frequent, not always justified red blood transfusions leading to the replacement of fetal haemoglobin with adult haemoglobin are also essential factors in ROP progression.

scholarly journals Frequency and Risk Factors for Retinopathy of Prematurity in Very Low Birth Weight Infants in NICU, BSMMU

2019 ◽  
Vol 32 (1) ◽  
pp. 54-61
Author(s):  
ANM Nurul Haque Bhuiyan ◽  
MA Mannan ◽  
Sanjoy Kumar Dey ◽  
Nuzhat Choudhury ◽  
Md Shameem ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Stepwise Logistic Regression ◽  
Low Birth Weight Infants ◽  
Department Of Ophthalmology ◽  
Elbw Neonates

Introduction: Retinopathy of prematurity (ROP) is emerging as an important avoidable cause of childhood blindness both in developed and developing countries that primarily affects premature and very low birth weight infants. There has been paucity of studies on this topic in Bangladesh and there is no national prevalence data on ROP to understand the real burden of the disease. Hence this study has been undertaken to see its frequency and risk factors for ROP in very low weight infants admitted in NICU, BSMMU. Objectives: To find out the frequency and risk factors for ROP in very low birth weight infants admitted in NICU, BSMMU. Methodology: It was a prospective observational study and was carried out in the Department of Neonatology and Department of Ophthalmology, BSMMU from January 2014 to June 2015. Considering all inclusion and exclusion criteria total 162 very low birth weight neonates were enrolled in the study. ROP screening was performed as per unit protocol. All eye examinations were undertaken by experienced ophthalmologist who was especially trained in ROP. Result: Out of 162 study population, one hundred forty fore (88.9%) were very low birth weight, 18(11.1%) were extremely low birth weight and mean birth weight was 1294.35 (SD: 180.96) g. Frequency of ROP was 38(23.5%), where 30(20.83%) among very low birth weight (VLBW) and 8(44.44%) were among ELBW neonates. Out of 38 ROP cases, 5(13%) had stage 1 retinopathy, 3(8%) had stage 2 retinopathy, 16(42.1%) had stage 3 and remaining 14(36.8%) neonates had APROP. On univariate analysis seventeen factors were found to be significant but on stepwise logistic regression analysis only lower gestational age [OR=5.014; CI(95%),2.160-11.640, P=.001] and use of mechanical ventilator [OR=1.925; CI(95%),1.133-3.269, P=.015] was found to be the most significant for causation of ROP. Conclusion: The overall frequency of ROP was 38(23.5%), where as 30(20.83%) were among VLBW and 8(44.44%) were among ELBW neonates. Prevention of prematurity and judicious use of ventilator may reduce the incidence and severity of ROP TAJ 2019; 32(1): 54-61

scholarly journals Genetic Variants Associated With Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

2014 ◽  
Vol 55 (10) ◽  
pp. 6194 ◽  
Author(s):  
M. Elizabeth Hartnett ◽  
Margaux A. Morrison ◽  
Silvia Smith ◽  
Tammy L. Yanovitch ◽  
Terri L. Young ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Genetic Variants ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants

NEW CONCERNS ABOUT THERAPIES FOR RETINOPATHY OF PREMATURITY

PEDIATRICS ◽  
1996 ◽  
Vol 98 (6) ◽  
pp. A30-A30
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Patient Characteristics ◽  
Low Birth Weight Infants ◽  
Factors Associated ◽  
Corrected Visual Acuity

Purpose. Cryotherapy for retinopathy of prematurity (ROP) is effective in reducing the incidence of blindness in premature infants. However, macular complications associated with successful treatment have not yet been well studied. Methods. Eighteen very low birth weight (&lt;1251 g) infants (32 eyes) who received cryotherapy for ROP were examined serially for regression of disease and for development of macular abnormalities. Patient characteristics and treatment factors were evaluated to identify risk factors associated with the development of macular abnormalities after successful cryotherapy. Results. Eleven of 32 eyes (34.4%) that had undergone cryotherapy developed significant macular abnormalities, including macular coloboma-like change (six eyes), macular hyperpigmentation (two eyes), irregularly mottled macular hyperpigmentation and hypopigmentation (two eyes), and macular hyperpigmentation and hypopigmentation with subretinal proliferation (one eye). Corrected visual acuity in affected eyes ranged from 0.15 to 0.03 (20/133 to 20/666) compared with 1.0 to 0.2 (20/20 to 20/100) in treated eyes without macular abnormality (P = .0002). No difference in gestational age was noted between infants who did or did not develop macular coloboma-like lesions or pigment abnormalities. Eyes with macular abnormality had more posterior disease (P = .037) and received significantly more cryotherapy than did eyes without macular abnormality (P = .0005). Conclusions. In very low birth weight infants receiving cryotherapy for ROP, development of macular coloboma-like lesions and macular pigment abnormalities were related to greater severity of ROP and a greater amount of cryotherapy. Macular abnormalities were associated with markedly worse visual outcomes than were treated eyes without macular abnormality.

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