High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia

Leukemia ◽

10.1038/sj.leu.2404404 ◽

2006 ◽

Vol 20 (11) ◽

pp. 1955-1962 ◽

Author(s):

T V Ch Skärby ◽

◽

H Anderson ◽

J Heldrup ◽

J A Kanerva ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Cure Rate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia

Yearbook of Oncology ◽

10.1016/s1040-1741(08)79189-9 ◽

2008 ◽

Vol 2008 ◽

pp. 265-266

Author(s):

R.J. Arceci

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Cure Rate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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Transient encephalopathy following high-dose methotrexate treatment in childhood acute lymphoblastic leukemia

Leukemia ◽

10.1038/sj.leu.2401098 ◽

1998 ◽

Vol 12 (8) ◽

pp. 1176-1181 ◽

Author(s):

JE Rubnitz ◽

MV Relling ◽

PL Harrison ◽

JT Sandlund ◽

RC Ribeiro ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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Oral Mucositis in Children with Acute Lymphoblastic Leukemia After High-Dose Methotrexate Treatment Without Delayed Elimination of Methotrexate: Relation to Pharmacokinetic Parameters of Methotrexate

Pediatric Hematology and Oncology ◽

10.3109/08880019609030842 ◽

1996 ◽

Vol 13 (4) ◽

pp. 359-367 ◽

Author(s):

Charlotte Rask ◽

Freidoun Albertioni ◽

Henrik Schrøder ◽

Curt Peterson

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Oral Mucositis ◽

Lymphoblastic Leukemia ◽

Pharmacokinetic Parameters ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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Intracranial Hemorrhage Following Oral Low-Dose Methotrexate After Multiple Toxicities Caused by High-Dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01072 ◽

2019 ◽

Vol 10 ◽

Author(s):

Ning Xin ◽

Zhou Fen ◽

Cheng Li ◽

Xiao Yan ◽

Jin Runming

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Intracranial Hemorrhage ◽

Low Dose ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Plasma creatinine as predictor of delayed elimination of high‐dose methotrexate in childhood acute lymphoblastic leukemia: A Danish population‐based study

Pediatric Blood & Cancer ◽

10.1002/pbc.27637 ◽

2019 ◽

Vol 66 (6) ◽

pp. e27637 ◽

Author(s):

Diana Schmidt ◽

Kim Kristensen ◽

Henrik Schroeder ◽

Peder Skov Wehner ◽

Steen Rosthøj ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Population Based ◽

Childhood Acute Lymphoblastic Leukemia ◽

Plasma Creatinine ◽

High Dose ◽

High Dose Methotrexate ◽

Danish Population ◽

Population Based Study ◽

Dose Methotrexate

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HEMOSTATIC SIDE EFFECTS OF HIGH-DOSE METHOTREXATE IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

Pediatric Hematology and Oncology ◽

10.1080/08880010490264064 ◽

2004 ◽

Vol 21 (1) ◽

pp. 77-83 ◽

Author(s):

Tunc Fisgin ◽

Nese Yarali ◽

Abdurrahman Kara ◽

Ceyhun Bozkurt ◽

Dilek Birgen ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Side Effects ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Rationale for High-Dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

Treatment of Acute Leukemias ◽

10.1385/1-59259-307-0:339 ◽

2003 ◽

pp. 339-356 ◽

Author(s):

Timothy L. Brenner ◽

William E. Evans

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Association of ABCC2 −24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia

PLoS ONE ◽

10.1371/journal.pone.0082681 ◽

2014 ◽

Vol 9 (1) ◽

pp. e82681 ◽

Author(s):

Yan Liu ◽

You Yin ◽

Qi Sheng ◽

Xiaotong Lu ◽

Fang Wang ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Plasma Concentrations ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Impact ofSLCO1B1521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate

Pediatric Blood & Cancer ◽

10.1002/pbc.25191 ◽

2014 ◽

Vol 61 (12) ◽

pp. 2203-2207 ◽

Author(s):

Hua-Nian Zhang ◽

Xue-Lian He ◽

Cheng Wang ◽

Yang Wang ◽

Yu-Jun Chen ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Leucovorin Rescue ◽

Risk Of Relapse

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Plasma homocysteine, methionine and S-adenosylhomocysteine levels following high-dose methotrexate treatment in pediatric patients with acute lymphoblastic leukemia or Burkitt lymphoma: association with hepatotoxicity

Leukemia & Lymphoma ◽

10.3109/10428194.2013.850684 ◽

2013 ◽

Vol 55 (7) ◽

pp. 1591-1595 ◽

Author(s):

Masaru Kubota ◽

Rieko Nakata ◽

Souichi Adachi ◽

Ken-Ichiro Watanabe ◽

Toshio Heike ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Burkitt Lymphoma ◽

Pediatric Patients ◽

Lymphoblastic Leukemia ◽

Plasma Homocysteine ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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