Rationale for High-Dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

Treatment of Acute Leukemias ◽

10.1385/1-59259-307-0:339 ◽

2003 ◽

pp. 339-356 ◽

Author(s):

Timothy L. Brenner ◽

William E. Evans

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Intracranial Hemorrhage Following Oral Low-Dose Methotrexate After Multiple Toxicities Caused by High-Dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01072 ◽

2019 ◽

Vol 10 ◽

Author(s):

Ning Xin ◽

Zhou Fen ◽

Cheng Li ◽

Xiao Yan ◽

Jin Runming

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Intracranial Hemorrhage ◽

Low Dose ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Plasma creatinine as predictor of delayed elimination of high‐dose methotrexate in childhood acute lymphoblastic leukemia: A Danish population‐based study

Pediatric Blood & Cancer ◽

10.1002/pbc.27637 ◽

2019 ◽

Vol 66 (6) ◽

pp. e27637 ◽

Author(s):

Diana Schmidt ◽

Kim Kristensen ◽

Henrik Schroeder ◽

Peder Skov Wehner ◽

Steen Rosthøj ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Population Based ◽

Childhood Acute Lymphoblastic Leukemia ◽

Plasma Creatinine ◽

High Dose ◽

High Dose Methotrexate ◽

Danish Population ◽

Population Based Study ◽

Dose Methotrexate

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HEMOSTATIC SIDE EFFECTS OF HIGH-DOSE METHOTREXATE IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

Pediatric Hematology and Oncology ◽

10.1080/08880010490264064 ◽

2004 ◽

Vol 21 (1) ◽

pp. 77-83 ◽

Author(s):

Tunc Fisgin ◽

Nese Yarali ◽

Abdurrahman Kara ◽

Ceyhun Bozkurt ◽

Dilek Birgen ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Side Effects ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Association of ABCC2 −24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia

PLoS ONE ◽

10.1371/journal.pone.0082681 ◽

2014 ◽

Vol 9 (1) ◽

pp. e82681 ◽

Author(s):

Yan Liu ◽

You Yin ◽

Qi Sheng ◽

Xiaotong Lu ◽

Fang Wang ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Plasma Concentrations ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate

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Impact ofSLCO1B1521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate

Pediatric Blood & Cancer ◽

10.1002/pbc.25191 ◽

2014 ◽

Vol 61 (12) ◽

pp. 2203-2207 ◽

Author(s):

Hua-Nian Zhang ◽

Xue-Lian He ◽

Cheng Wang ◽

Yang Wang ◽

Yu-Jun Chen ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Leucovorin Rescue ◽

Risk Of Relapse

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High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia

Yearbook of Oncology ◽

10.1016/s1040-1741(08)79189-9 ◽

2008 ◽

Vol 2008 ◽

pp. 265-266

Author(s):

R.J. Arceci

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Cure Rate ◽

Dose Methotrexate ◽

Methotrexate Treatment

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High-dose methotrexate therapy of childhood acute lymphoblastic leukemia: Lack of relation between serum methotrexate concentration and creatinine clearance

Pediatric Blood & Cancer ◽

10.1002/pbc.20032 ◽

2004 ◽

Vol 43 (1) ◽

pp. 17-22 ◽

Author(s):

Pilar Joannon ◽

Iris Oviedo ◽

Myriam Campbell ◽

Juan Tordecilla

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Creatinine Clearance ◽

Lymphoblastic Leukemia ◽

Methotrexate Therapy ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Methotrexate Concentration

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Anti-leukemic treatment-induced neurotoxicity in long-term survivors of childhood acute lymphoblastic leukemia: impact of reduced central nervous system radiotherapy and intermediate- to high-dose methotrexate

Leukemia & Lymphoma ◽

10.1080/10428194.2018.1434879 ◽

2018 ◽

Vol 59 (10) ◽

pp. 2342-2351 ◽

Author(s):

Olga Zając-Spychała ◽

Mikolaj Pawlak ◽

Katarzyna Karmelita-Katulska ◽

Jakub Pilarczyk ◽

Katarzyna Jończyk-Potoczna ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Long Term Survivors

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Intermediate Dose Methotrexate Is as Effective as High Dose Methotrexate in Preventing Isolated Testicular Relapse in Childhood Acute Lymphoblastic Leukemia

Journal of Pediatric Hematology/Oncology ◽

10.1097/00043426-199809000-00007 ◽

1998 ◽

Vol 20 (5) ◽

pp. 444-450 ◽

Author(s):

Michael Dördelmann ◽

Alfred Reiter ◽

Martin Zimmermann ◽

Rüdiger Fengler ◽

Günter Henze ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

Intermediate Dose

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Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia

Leukemia & Lymphoma ◽

10.3109/10428194.2011.639880 ◽

2012 ◽

Vol 53 (6) ◽

pp. 1096-1104 ◽

Author(s):

Nina Erčulj ◽

Barbara Faganel Kotnik ◽

Maruša Debeljak ◽

Janez Jazbec ◽

Vita Dolžan

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

High Dose ◽

High Dose Methotrexate ◽

Dose Methotrexate ◽

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