scholarly journals The Selective mGlu5 Receptor Antagonist MTEP, Similar to NMDA Receptor Antagonists, Induces Social Isolation in Rats

2006 ◽  
Vol 32 (3) ◽  
pp. 562-576 ◽  
Author(s):  
Eliza Koros ◽  
Holger Rosenbrock ◽  
Gerald Birk ◽  
Carmen Weiss ◽  
Frank Sams-Dodd
Keyword(s):  
Nmda Receptor ◽  
Receptor Antagonist ◽  
Social Isolation ◽  
Nmda Receptor Antagonists ◽  
Receptor Antagonists ◽  
Mglu5 Receptor

NMDA receptor antagonists attenuate the proconvulsant effect of juvenile social isolation in male mice

2016 ◽  
Vol 121 ◽  
pp. 158-168 ◽  
Author(s):  
Shayan Amiri ◽  
Arya Haj-Mirzaian ◽  
Hossein Amini-khoei ◽  
Majid Momeny ◽  
Armin Shirzadian ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Social Isolation ◽  
Nmda Receptor Antagonists ◽  
Male Mice ◽  
Receptor Antagonists

Ketamine and other NMDA receptor antagonists

2010 ◽  
pp. 115-124
Author(s):  
Marie Fallon ◽  
Cameron Fergus ◽  
Barry J.A. Laird
Keyword(s):  
Nmda Receptor ◽  
Receptor Antagonist ◽  
Nmda Receptor Antagonist ◽  
Nmda Receptor Antagonists ◽  
Receptor Antagonists ◽  
Oral Ketamine ◽  
First Pass Metabolism ◽  
First Pass ◽  
Pass Metabolism

Ketamine is a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist and is most effective in pain states where hyper-excitability is established Ketamine undergoes first-pass metabolism to norketamine, which is a more potent analgesic than ketamine. This can explain why oral ketamine is more potent than parenteral ketamine...

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