scholarly journals Nosocomial and Community-Acquired Spontaneous Bacterial Peritonitis in patients with liver cirrhosis in China: Comparative Microbiology and Therapeutic Implications

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lei Shi ◽  
Dan Wu ◽  
Lei Wei ◽  
Suxia Liu ◽  
Peng Zhao ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Spontaneous Bacterial Peritonitis ◽  
Pathogenic Bacteria ◽  
Clinical Symptoms ◽  
Resistance Rate ◽  
Coagulase Negative Staphylococcus ◽  
Therapeutic Implications ◽  
Bacterial Peritonitis ◽  
Microbiological Characteristics ◽  
Susceptibility Tests

Abstract Spontaneous bacterial peritonitis (SBP) is a common complication of liver cirrhosis. This study was performed to compare the microbiological characteristics of nosocomial and community-acquired episodes of bacterial peritonitis in China. Five hundred and seventy-five strains were isolated from the ascitic fluid of cirrhotic patients from the Beijing 302 Hospital from January 2014 to December 2014. The patients in the community-acquired SBP (n = 264) and the nosocomial SBP (n = 311) groups exhibited significant differences in clinical symptoms (P < 0.01). In both groups, most of the bacteria were Escherichia coli, Klebsiella pneumoniae, coagulase-negative staphylococcus and Enterococcus. There were more frequent gram-positive cocci (G+ C) in the nosocomial group (n = 170). Compared with the community-acquired group, the proportion of Enterococcus was significantly increased in the nosocomial group (9.0% vs. 16.6%, P < 0.05). The resistance rate of the main pathogenic bacteria to the recommended first-line drug in the guideline was very high. Community-acquired and nosocomial SBP groups exhibited differences in clinical symptoms and antibiotic susceptibility tests. Optimal treatments should be provided for these patients. We recommend that cefoperazone/sulbactam or piperacillin/tazobactam should be used for the empirical treatment of SBP.

scholarly journals FREQUENCY OF SYMPTOMATIC SPONTANEOUS BACTERIAL PERITONITIS AND ASSOCIATED CLINICAL PARAMETERS IN PATIENTS WITH LIVER CIRRHOSIS

2021 ◽  
Vol 71 (5) ◽  
pp. 1598-1602
Author(s):  
Syed Fayyaz Mehmood Gilani ◽  
Fayyaz Hassan ◽  
Fuad Ahmad Siddiqui ◽  
Syed Anees Ahmed Gardezi
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Ascitic Fluid ◽  
Spontaneous Bacterial Peritonitis ◽  
Clinical Symptoms ◽  
International Normalized Ratio ◽  
Military Hospital ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Asymptomatic Patients

Objective: To study association between spontaneous bacterial peritonitis and clinical symptoms in liver cirrhosis. Study Design: cross-sectional study. Place and Duration of Study: Combined Military Hospital Kharian, from Jul 2019 to Apr 2020. Methodology: A total of 122 patients of liver cirrhosis (irrespective of aetiology), presented with various clinical symptoms such as fever, pain abdomen and hepatic encephalopathy were randomly selected. Patients between 18-80 years of age, were included in the study. Asymptomatic patients, with ascites other than liver cirrhosis were excluded. Spontaneous Bacterial Peritonitis was defined as positive ascitic fluid culture and/or ascitic polymorphonuclear leukocyte ≥250 cells/mm3 in ascitic fluid. Results: Of the 122 randomly selected patients, the mean age was 56.5 ± 20.2 years. Forty-Five (46.8%) were male and 67 (54.2%) patients were female. Chronic Hepatitis C was the commonest cause of liver cirrhosis (92%). The frequency of spontaneous bacterial peritonitis was 37.7%. Majority, (83%) of the culture positive ascitic isolate was Gram negative bacilli and E.coli (72%) being the commonest organism isolated. Severe ascites, high International Normalized Ratio (INR), hepatic encephalopathy, fever, low ascetic fluid protein count, high serum bilirubin and creatinine were considered to be independent predictor of Spontaneous Bacterial Peritonitis. Conclusion: Clinical symptoms of fever, hepatic encephalopathy, severe ascites, International Normalized ratio high and deranged renal profile was highly suggestive of Spontaneous Bacterial Peritonitis in cirrhotic patients.

scholarly journals Spontaneous Bacterial Peritonitis Caused byHafnia alveiin a Patient with Liver Cirrhosis

2010 ◽  
Vol 42 (6) ◽  
pp. 420 ◽  
Author(s):  
Sang Kyung Jung ◽  
June Sung Lee ◽  
Kyung Ah Kim ◽  
Young Doo Kim ◽  
Yoon Jung Jwa ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Spontaneous Bacterial Peritonitis ◽  
Bacterial Peritonitis

scholarly journals Renal impairment after Spontaneous Bacterial Peritonitis (SBP) in cirrhotic population.

2019 ◽  
Vol 26 (12) ◽  
pp. 2235-2240
Author(s):  
Asif Javaid Wakani ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan ◽  
Faqir Muhammad Awan
Keyword(s):  
Liver Cirrhosis ◽  
Renal Impairment ◽  
Serum Creatinine ◽  
Spontaneous Bacterial Peritonitis ◽  
National Hospital ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Serum Blood Urea Nitrogen ◽  
Patient’S Information ◽  
The Mean

Objectives: To evaluate the frequency of renal impairment after spontaneous bacterial peritonitis (SBP) in cirrhotic population. Study Design: The study was conducted as Descriptive Cross-Sectional. Setting: Liaquat National Hospital Karachi. Period: For six months (October 01, 2015 to March 31, 2016). Methodology: The subjects with liver cirrhosis spontaneous bacterial peritonitis (SBP) were evaluated for serum creatinine and serum blood urea nitrogen (BUN) for evaluation of renal impairment while the patient’s information was recorded on proforma and analyzed in SPSS-15.0. Results: The mean ±SD of age, BUN and serum creatinine for whole population was 50.69±10.69 years, 22.4197±11.64742 and 1.2207±0.92535. Renal impairment was detected in 40 (27.2%) individuals while it is normal in 107 (72.8%) subjects. Conclusion: The renal impairment after SBP in cirrhotic population is higher in present study.

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