Chapter 1. The Chemical Genetic Approach: The Interrogation of Biological Mechanisms with Small Molecule Probes

2010 ◽  
pp. 1-32
Author(s):  
Martin Fisher ◽  
Adam Nelson
Keyword(s):  
Small Molecule ◽  
Genetic Approach ◽  
Biological Mechanisms ◽  
Chemical Genetic ◽  
Small Molecule Probes

scholarly journals Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems

2021 ◽  
Vol 50 (2) ◽  
pp. 702-734
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Ping Li ◽  
Bo Tang ◽  
Tony D. James
Keyword(s):  
Small Molecule ◽  
Biological Systems ◽  
Two Photon ◽  
Small Molecule Probes ◽  
Recent Advances ◽  
Design Construction

In this tutorial review, we will explore recent advances for the design, construction and application of two-photon excited fluorescence (TPEF)-based small-molecule probes.

Controlled self-assembly of small molecule probes and the related applications in bioanalysis

2016 ◽  
Vol 76 ◽  
pp. 38-53 ◽  
Author(s):  
Yongxin Li ◽  
Huipeng Zhou ◽  
Jian Chen ◽  
Sohail Anjum Shahzad ◽  
Cong Yu
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Small Molecule Probes

Forward chemical genetic approach identifies new role for GAPDH in insulin signaling

2006 ◽  
Vol 3 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Jaeki Min ◽  
Yun Kyung Kim ◽  
Patricia G Cipriani ◽  
Mira Kang ◽  
Sonya M Khersonsky ◽  
...  
Keyword(s):  
Insulin Signaling ◽  
Genetic Approach ◽  
Chemical Genetic

“Click” synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases

2006 ◽  
pp. 3783-3785 ◽  
Author(s):  
Jun Wang ◽  
Mahesh Uttamchandani ◽  
Junqi Li ◽  
Mingyu Hu ◽  
Shao Q. Yao
Keyword(s):  
Small Molecule ◽  
Matrix Metalloproteases ◽  
Small Molecule Probes ◽  
Click Synthesis
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