The volumetric determination of nitric acid in mixed and refuse acids: a reference half-cell for use in titrations with ferrous ammonium sulphate

The Analyst ◽  
1948 ◽  
Vol 73 (873) ◽  
pp. 669 ◽  
Author(s):  
C. R. N. Strouts ◽  
C. A. Macinnes
Keyword(s):  
Nitric Acid ◽  
Ammonium Sulphate ◽  
Ferrous Ammonium Sulphate ◽  
Half Cell ◽  
Volumetric Determination ◽  
Ferrous Ammonium

Microanalytical determination of calcium, phosphate, and arsenate including kinetics of formation of molybdenum blue from reduction of molybdoarsenic acid by ferrous ammonium sulphate

1987 ◽  
Vol 65 (6) ◽  
pp. 1313-1315 ◽  
Author(s):  
U. S. Rat ◽  
T. S. B. Narasaraju
Keyword(s):  
Calcium Phosphate ◽  
Ammonium Sulphate ◽  
Ferrous Ammonium Sulphate ◽  
Molybdenum Blue ◽  
Spectrophotometric Methods ◽  
Rate Determining Step ◽  
Kinetics Of Formation ◽  
Ferrous Ammonium ◽  
Kinetics Of

A method for the microdetermination of calcium, phosphate, and arsenate in mixtures of the three has been developed. In an aliquot of the mixture calcium was determined complexometrically using EDTA. Phosphate and arsenate were determined in second and third aliquots, respectively, using spectrophotometric methods. The interference of arsenate in the determination of phosphate was avoided by masking arsenate with thiosulphate. The kinetics of formation of molybdenum blue from molybdoarsenic acid by reduction with ferrous ammonium sulphate was also studied. The rate-determining step was found to be the reduction of molybdoarsenic acid with iron(II); the reaction was first order in iron(II) and arsenate over the concentration ranges studied. Values found for the enthalpy, entropy, and free energy of activation were 22, 0.05, and 7.5 kcal, respectively.

scholarly journals SPECTROSCOPIC AND VOLUMETRIC TECHNIQUES FOR THE ESTIMATION OF IVABRADINE IMPURITY 3,3'-(PROPANE-1,3-DIYL)BIS(7,8-DIMETHOXY-1,3,4,5-TETRAHYDRO-2H-BENZO[D]AZEPIN-2-ONE)

2019 ◽  
pp. 216-218
Author(s):  
S. ANIL KUMAR ◽  
B. L. BHASKAR
Keyword(s):  
Ammonium Sulphate ◽  
Parent Drug ◽  
Ferrous Ammonium Sulphate ◽  
Subsequent Reaction ◽  
Drug Molecule ◽  
Reagent Blank ◽  
Colored Complex ◽  
Coloured Complex ◽  
Ferrous Ammonium

Objective: Two simple and sensitive techniques - one spectrophotometric and one titrimetric- have been developed for the determination of 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) commonly known as ivabradine impurity-9 (IVA-9). Methods: The spectrophotometric method is based on the oxidation of drug impurity by excess cerium (IV) sulphate in acidic medium and the subsequent reaction of the remaining Ce(IV) with a known amount of ferrous ammonium sulphate. The resultant ferric ion is then made to react with thiocyanate in acid medium to form a brown coloured complex which is analyzed spectrophotometrically against the reagent blank. In the volumetric method, the un-reacted Ce(IV) is titrated against standard ferrous ammonium sulphate to estimate the quantity of IVA-9. Results: The colored complex showed an absorption maximum at 479 nm when measured  spectrophotometrically. The stated methods are validated statistically using the International Council for Harmonization guidelines-ICH Q2(R1) for precision and accuracy. The method showed a linear response from 0.5 to 100µg/ml with a correlation coefficient of 0.9985 Conclusion : No estimation techniques have been reported to date for the determination of this molecule. The proposed techniques may be used for the routine quantification in its pure form and also in presence of its parent drug molecule Ivabradine.

Radiolysis of ferrous ammonium sulphate in alkali nitrate and alkali halide matrices

1973 ◽  
Vol 20 (3) ◽  
pp. 153-157 ◽  
Author(s):  
V. S. Khare ◽  
V. Ramshesh ◽  
K. S. Venkateswarlu
Keyword(s):  
Ammonium Sulphate ◽  
Alkali Halide ◽  
Ferrous Ammonium Sulphate ◽  
Ferrous Ammonium

IV. Note on the volumetric determination of uric acid

1888 ◽  
Vol 44 (266-272) ◽  
pp. 284-286
Keyword(s):  
Uric Acid ◽  
Nitric Acid ◽  
Silver Nitrate ◽  
Sodium Carbonate ◽  
Silver Chloride ◽  
Volumetric Determination

Dr. Haycraft has recently proposed a method for the volumetric determination of uric acid in urine ( ‘ Brit. Med. Journ.,’ 1885, 2, p. 1100) which has great advantages over all former methods in that it is much quicker and easier to manage. The uric acid from 25 c. c. of urine is precipitated by silver nitrate after previous addition of sodium carbonate (to prevent reduction) and ammonia (to dissolve silver chloride, & c.); this precipitate is then collected, washed, and dissolved in nitric acid, and the amount of silver present in this solu­tion ascertained by Volhard’s method, i . e ., titration with ammonium sulphocyanate ; from this the amount of uric acid can be calculated.

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