Correlation of the β-sheet crystal size in silk fibers with the protein amino acid sequence

Soft Matter ◽  
2007 ◽  
Vol 3 (7) ◽  
pp. 877-882 ◽  
Author(s):  
Lawrence F. Drummy ◽  
B. L. Farmer ◽  
Rajesh R. Naik

1987 ◽  
Vol 165 (1) ◽  
pp. 200-207 ◽  
Author(s):  
Viktor Krchňák ◽  
Otakar Mach ◽  
Antonín Malý


1990 ◽  
Vol 55 (3) ◽  
pp. 950-955 ◽  
Author(s):  
Trudy J. Milne ◽  
Annette R. Atkins ◽  
Juanita A. Warren ◽  
Wendy P. Auton ◽  
Ross Smith




1990 ◽  
Vol 192 (2) ◽  
pp. 507-513 ◽  
Author(s):  
Rodolfo BERNI ◽  
Monica STOPPINI ◽  
Maria Carla ZAPPONI ◽  
Maria Laura MELONI ◽  
Hugo L. MONACO ◽  
...  


2007 ◽  
Vol 82 (20) ◽  
pp. 10318-10320 ◽  
Author(s):  
W. W. Laegreid ◽  
M. L. Clawson ◽  
M. P. Heaton ◽  
B. T. Green ◽  
K. I. O'Rourke ◽  
...  

ABSTRACT Variation in the ovine prion protein amino acid sequence influences scrapie progression, with sheep homozygous for A136R154Q171 considered susceptible. This study examined the association of survival time of scrapie-exposed ARQ sheep with variation elsewhere in the ovine prion gene. Four single nucleotide polymorphism alleles were associated with prolonged survival. One nonsynonymous allele (T112) was associated with an additional 687 days of survival for scrapie-exposed sheep compared to M112 sheep (odds ratio, 42.5; P = 0.00014). The only two sheep homozygous for T112 (TARQ) did not develop scrapie, suggesting that the allelic effect may be additive. These results provide evidence that TARQ sheep are genetically resistant to development of classical scrapie.



Author(s):  
Jonathan King ◽  
Cammie Haase-Pettingell ◽  
Ryan Simkovsky ◽  
Peter Weigele


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