Development and optimization of a multivariate RP-UPLC method for determination of telmisartan and its related substances by applying a two-level factorial design approach: application to quality control study

2014 ◽  
Vol 6 (14) ◽  
pp. 5168 ◽  
Author(s):  
Nitin H. Dhekale ◽  
K. Hima Bindu ◽  
K. Y. Kirankumar ◽  
Anil H. Gore ◽  
Prashant V. Anbhule ◽  
...  
Keyword(s):  
Quality Control ◽  
Factorial Design ◽  
Design Approach ◽  
Related Substances ◽  
Quality Control Study ◽  
Control Study

Results of a quality control study of different analytical methods for determination of PCDD/PCDF in egg samples

Chemosphere ◽  
1996 ◽  
Vol 32 (1) ◽  
pp. 31-44 ◽  
Author(s):  
Rainer Malisch ◽  
Peter Schmid ◽  
Rolf Frommberger ◽  
Peter Fürst
Keyword(s):  
Quality Control ◽  
Analytical Methods ◽  
Quality Control Study ◽  
Control Study

scholarly journals Determination of Disk Diffusion and MIC Quality Control Guidelines for Solithromycin, a Novel Fluoroketolide Antibacterial, against Neisseria gonorrhoeae

2015 ◽  
Vol 53 (12) ◽  
pp. 3888-3890 ◽  
Author(s):  
Stefan Riedel ◽  
James E. Ross ◽  
David J. Farrell ◽  
Robert K. Flamm ◽  
Ronald N. Jones
Keyword(s):  
Quality Control ◽  
Susceptibility Testing ◽  
Disk Diffusion ◽  
Control Strain ◽  
Content Type ◽  
Disk Diffusion Testing ◽  
Quality Control Study ◽  
Agar Dilution ◽  
Control Study

This solithromycin quality control study was performed to establish quality control (QC) ranges for theN. gonorrhoeaeATCC 49226 control strain for MIC agar dilution testing (AD) and zones by disk diffusion testing (DD). The following ranges were established: AD, 0.03 to 0.25 μg/ml, and DD, 33 to 43 mm. In January 2015, the CLSI Subcommittee on Antimicrobial Susceptibility Testing approved these ranges, which will be important when evaluating solithromycin against clinical isolates ofN. gonorrhoeae.

Comparison of prostate cancer treatment in two institutions: a quality control study

1999 ◽  
Vol 45 (4) ◽  
pp. 1055-1062 ◽  
Author(s):  
Coen Rasch ◽  
Peter Remeijer ◽  
Peter C.M Koper ◽  
Gert J Meijer ◽  
Joep C Stroom ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Quality Control ◽  
Cancer Treatment ◽  
Prostate Cancer Treatment ◽  
Quality Control Study ◽  
Control Study

Measurement of histamine: A quality control study

1980 ◽  
Vol 66 (4) ◽  
pp. 295-298 ◽  
Author(s):  
Gerald J. Gleich ◽  
William M. Hull
Keyword(s):  
Quality Control ◽  
Quality Control Study ◽  
Control Study

scholarly journals Fast and selective HPLC-DAD method for determination of pholcodine and related substances

2011 ◽  
Vol 30 (2) ◽  
pp. 139 ◽  
Author(s):  
Ana Petkovska ◽  
Hristina Babunovska ◽  
Marina Stefova
Keyword(s):  
Quality Control ◽  
Degradation Products ◽  
Ammonium Hydroxide ◽  
Gradient Elution ◽  
Reversed Phase ◽  
Real Sample Analysis ◽  
Related Substances ◽  
Structural Analogues ◽  
Reliable Methods

Quality control of pharmaceuticals requires development of fast, efficient and reliable methods for determination of active compounds as well as known and very often unknown impurities within defined concentration ranges. In this work, a simple and rapid HPLC-UV-DAD method for identification and quantification of pholcodine process related impurities and some degradation products was developed and validated. Pholcodine and its five structural analogues such as morphine, codeine, thebaine, oripavine, and papaverine were separated in less than 10 minutes using reversed phase LiChrospher C-8 column. For optimal chromatographic performance with reproducible retention times, gradient elution with 2% ammonium hydroxide in water and acetonitrile was used. The method was validated by establishing its selectivity, specifity, sensitivity, linearity, intra- and inter-day precision and robustness. All tested parameters confirmed that the method is suitable for determination of pholcodine and its five impurities in pharmaceutical drug samples. The results obtained from real sample analysis give support to the suitability of the proposed method for the purpose of quality control.

Diffusing capacity of the lung for carbon monoxide test in children between 4 and 10 years old. A quality control study

2012 ◽  
Vol 13 ◽  
pp. S71
Author(s):  
G. Cantú-González ◽  
L. Gochicoa-Rangel ◽  
L. Torre-Bouscoulet ◽  
M. Silva-Cerón ◽  
A. Alejandre-García ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Quality Control ◽  
Diffusing Capacity ◽  
Quality Control Study ◽  
Control Study
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