Cholinium-based ionic liquids with pharmaceutically active anions

RSC Advances ◽  
2014 ◽  
Vol 4 (53) ◽  
pp. 28126-28132 ◽  
Author(s):  
João M. M. Araújo ◽  
Catarina Florindo ◽  
Ana B. Pereiro ◽  
Nicole S. M. Vieira ◽  
Ana A. Matias ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Exchange Reaction ◽  
Anion Exchange ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Biopharmaceutical Properties ◽  
Anion Exchange Reaction

Ionic liquids with cholinium-based active pharmaceutical ingredients (API-ILs) were preparedviaa simple and sustainable two-step anion exchange reaction. The resulting salts have improved upon the chemical, physical and biopharmaceutical properties of the parent APIs.

scholarly journals Epoxy-Containing Ionic Liquids with Tunable Functionality

Molecules ◽  
2019 ◽  
Vol 24 (14) ◽  
pp. 2591
Author(s):  
Tetsuya Tsuda ◽  
Kazuki Iwasaki ◽  
Kohei Kumagai ◽  
Susumu Kuwabata
Keyword(s):  
Ionic Liquids ◽  
Ionic Conductivity ◽  
Physicochemical Properties ◽  
Exchange Reaction ◽  
Anion Exchange ◽  
Epoxy Group ◽  
Reaction Intermediates ◽  
Synthetic Route ◽  
The Future ◽  
Anion Exchange Reaction

New types of ionic liquids (ILs) with an epoxy group on a piperidinium-type cation were successfully synthesized by the simple anion exchange reaction of a solid 1-allyl-1-(oxiran-2-ylmethyl)piperidinium bromide, which was designed in this study. Unfortunately, the physicochemical properties, e.g., viscosity and ionic conductivity, of the ILs were inferior to those of common ILs such as 1-ethyl-3-methylimidazolium tetrafluoroborate ([C2mim][BF4]) and 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide ([C4mim][Tf2N]). However, the resulting ILs are of great interest as reaction intermediates: For example, the epoxy group on the cation could react with various reagents, including CO2. Consequently, the modification of the cation structure in the ILs was possible. This is particularly interesting because it is very difficult to modify commonly used ILs. The approach established in this article will provide a favorable synthetic route for creating novel functional ILs in the future.

Prodrug ionic liquids: functionalizing neutral active pharmaceutical ingredients to take advantage of the ionic liquid form

MedChemComm ◽  
2013 ◽  
Vol 4 (3) ◽  
pp. 559 ◽  
Author(s):  
O. Andreea Cojocaru ◽  
Katharina Bica ◽  
Gabriela Gurau ◽  
Asako Narita ◽  
Parker D. McCrary ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Active Pharmaceutical Ingredients ◽  
Liquid Form ◽  
Pharmaceutical Ingredients

Construction of uniform Co–Sn–X (X = S, Se, Te) nanocages with enhanced photovoltaic and oxygen evolution properties via anion exchange reaction

Nanoscale ◽  
2018 ◽  
Vol 10 (46) ◽  
pp. 22012-22024 ◽  
Author(s):  
Qian He ◽  
Shuolin Li ◽  
Shaowei Huang ◽  
Longqiang Xiao ◽  
Linxi Hou
Keyword(s):  
Exchange Reaction ◽  
Anion Exchange ◽  
Oxygen Evolution ◽  
Highly Efficient ◽  
Anion Exchange Reaction

Co–Sn–X (X = S, Se, Te) nanocages have been synthesized as highly efficient electrocatalysts for DSSCs and OER.

scholarly journals Ionic Liquids as Active Pharmaceutical Ingredients

ChemMedChem ◽  
2011 ◽  
Vol 6 (6) ◽  
pp. 975-985 ◽  
Author(s):  
Ricardo Ferraz ◽  
Luís C. Branco ◽  
Cristina Prudêncio ◽  
João Paulo Noronha ◽  
Željko Petrovski
Keyword(s):  
Ionic Liquids ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients

CsPbBr3 perovskite nanocrystals as highly selective and sensitive spectrochemical probes for gaseous HCl detection

2017 ◽  
Vol 5 (2) ◽  
pp. 309-313 ◽  
Author(s):  
Xiao Chen ◽  
Huawei Hu ◽  
Zhaoming Xia ◽  
Wei Gao ◽  
Wangyan Gou ◽  
...  
Keyword(s):  
Exchange Reaction ◽  
Anion Exchange ◽  
Ambient Conditions ◽  
Perovskite Nanocrystals ◽  
Anion Exchange Reaction

A rapid and facile gaseous anion-exchange reaction between CsPbBr3 perovskite nanocrystals and HCl vapor was carried out under the ambient conditions.

Sign in / Sign up

Export Citation Format

Share Document