Target-induced structure switching of aptamers facilitates strand displacement for DNAzyme recycling amplification detection of thrombin in human serum

The Analyst ◽  
2019 ◽  
Vol 144 (7) ◽  
pp. 2430-2435 ◽  
Author(s):  
Jin Li ◽  
Sujing Wang ◽  
Bingying Jiang ◽  
Yun Xiang ◽  
Ruo Yuan
Keyword(s):  
Human Serum ◽  
Strand Displacement ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Target-induced sequence proximity leads to strand displacement formation of DNAzymes for amplified detection of thrombin in human serum.

Target-induced structure switching of DNA for label-free and ultrasensitive electrochemiluminescent detection of proteins

2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai
Keyword(s):  
Dna Structure ◽  
Label Free ◽  
Switching Strategy ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Exo Iii ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.

An off/on thrombin activated energy driven molecular machine for sensitive detection of human thrombin via non-enzymatic catalyst recycling amplification

The Analyst ◽  
2020 ◽  
Vol 145 (21) ◽  
pp. 6868-6874 ◽  
Author(s):  
Zhang Zhang ◽  
Min Mei ◽  
Juan Yao ◽  
Ting Ye ◽  
Jing Quan ◽  
...  
Keyword(s):  
Displacement Reaction ◽  
Strand Displacement ◽  
Catalyst Recycling ◽  
Enzyme Catalyst ◽  
Human Thrombin ◽  
Dna Machine ◽  
Recycling Amplification ◽  
Amplification Strategy ◽  
Enzymatic Catalyst ◽  
Strand Displacement Reaction

A novel dual signal on/off amplification strategy by integrating thrombin mediated strand displacement reaction and non-enzyme catalyst recycling DNA machine.

An efficient target–intermediate recycling amplification strategy for ultrasensitive fluorescence assay of intracellular lead ions

2017 ◽  
Vol 53 (54) ◽  
pp. 7525-7528 ◽  
Author(s):  
Zhi-Bin Wen ◽  
Wen-Bin Liang ◽  
Ying Zhuo ◽  
Cheng-Yi Xiong ◽  
Ying-Ning Zheng ◽  
...  
Keyword(s):  
Fluorescence Assay ◽  
Lead Ions ◽  
Strand Displacement ◽  
Displacement Reactions ◽  
Intracellular Lead ◽  
Recycling Amplification ◽  
Amplification Strategy

An ultrasensitive fluorescence assay for intracellular Pb2+ determination was proposed through target–intermediate recycling amplification based on metal-assisted DNAzyme catalysis and strand displacement reactions.

A label-free fluorescent sensor for Hg2+based on target-induced structure-switching of G-quadruplex

2014 ◽  
Vol 6 (3) ◽  
pp. 662-665 ◽  
Author(s):  
Yunfeng Bai ◽  
Feng Feng ◽  
Lu zhao ◽  
Zezhong Chen ◽  
Haiyan Wang ◽  
...  
Keyword(s):  
Fluorescent Sensor ◽  
Label Free ◽  
G Quadruplex ◽  
Structure Switching ◽  
Induced Structure

A novel label-free aptasensor based on target-induced structure switching of aptamer-functionalized mesoporous silica nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (122) ◽  
pp. 100960-100967 ◽  
Author(s):  
Lili Du ◽  
Yu Zhang ◽  
Yan Du ◽  
Dongzhi Yang ◽  
Fenglei Gao ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
High Performance ◽  
Mesoporous Silica Nanoparticles ◽  
Label Free ◽  
Functionalized Mesoporous Silica ◽  
Structure Switching ◽  
Induced Structure

A strategy for high-performance liquid chromatography detection of adenosine triphosphate was developed based on mesoporous silica nanoparticles functionalized with an aptamer as a cap.

Target-induced structure switching of a hairpin aptamer for the fluorescence detection of zeatin

2016 ◽  
Vol 8 (30) ◽  
pp. 5957-5961 ◽  
Author(s):  
Chen Liu ◽  
Jinyang Chen ◽  
Guobin Mao ◽  
Chen Su ◽  
Xinghu Ji ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Fluorescence Biosensor ◽  
Structure Switching ◽  
Induced Structure

A versatile, simple and sensitive fluorescence biosensor is developed for zeatin detection based on target-induced structure switching of hairpin aptamer.

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