A novel label-free fluorescent molecular beacon for the detection of 3′–5′ exonuclease enzymatic activity using DNA-templated copper nanoclusters

2017 ◽  
Vol 41 (18) ◽  
pp. 9718-9723 ◽  
Author(s):  
Jia Ge ◽  
Zhen-Zhen Dong ◽  
Dong-Mei Bai ◽  
Lin Zhang ◽  
Ya-Lei Hu ◽  
...  
Keyword(s):  
Enzymatic Activity ◽  
Molecular Beacon ◽  
Label Free ◽  
Copper Nanoclusters ◽  
Selective Determination ◽  
Highly Sensitive ◽  
Exo Iii

A label-free biosensor was developed for highly sensitive and selective determination of Exo III based on poly(T) molecular beacon-templated CuNPs.

Synthesis of fluorescent ionic liquid-functionalized silicon nanoparticles with tunable amphiphilicity and selective determination of Hg2+

2018 ◽  
Vol 6 (48) ◽  
pp. 8214-8220 ◽  
Author(s):  
Quan Li ◽  
Kaite Peng ◽  
Yanzhen Lu ◽  
Aoxin Li ◽  
Fenfang Che ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Silicon Nanoparticles ◽  
Selective Detection ◽  
Label Free ◽  
Selective Determination ◽  
Highly Sensitive

Label-free fluorescent ionic liquid-functionalized silicon nanoparticles with tunable amphiphilicity for highly sensitive and selective detection of Hg2+ were synthesized.

scholarly journals A highly sensitive biosensor based on methacrylated graphene oxide-grafted polyaniline for ascorbic acid determination

2020 ◽  
Vol 9 (1) ◽  
pp. 760-767 ◽  
Author(s):  
Seyed Morteza Naghib ◽  
Farahnaz Behzad ◽  
Mehdi Rahmanian ◽  
Yasser Zare ◽  
Kyong Yop Rhee
Keyword(s):  
Ascorbic Acid ◽  
Graphene Oxide ◽  
Current Response ◽  
Functionalized Graphene ◽  
Serum Samples ◽  
Promising Candidate ◽  
Graphene Nanocomposites ◽  
Selective Determination ◽  
Highly Sensitive

AbstractFunctionalized graphene-based nanocomposites have opened new windows to address some challenges for increasing the sensitivity, accuracy and functionality of biosensors. Polyaniline (PANI) is one of the most potentially promising and technologically important conducting polymers, which brings together the electrical features of metals with intriguing properties of plastics including facile processing and controllable chemical and physical properties. PANI/graphene nanocomposites have attracted intense interest in various fields due to unique physicochemical properties including high conductivity, facile preparation and intriguing redox behavior. In this article, a functionalized graphene-grafted nanostructured PANI nanocomposite was applied for determining the ascorbic acid (AA) level. A significant current response was observed after treating the electrode surface with methacrylated graphene oxide (MeGO)/PANI nanocomposite. The amperometric responses showed a robust linear range of 8–5,000 µM and detection limit of 2 µM (N = 5). Excellent sensor selectivity was demonstrated in the presence of electroactive components interfering species, commonly found in real serum samples. This sensor is a promising candidate for rapid and selective determination of AA.

Sensitive and selective determination of hydroxychloroquine in the presence of uric acid using a new nanostructure self-assembled monolayer modified electrode: optimization by multivariate data analysis

The Analyst ◽  
2014 ◽  
Vol 139 (16) ◽  
pp. 4064-4072 ◽  
Author(s):  
Asma Khoobi ◽  
Sayed Mehdi Ghoreishi ◽  
Mohsen Behpour
Keyword(s):  
Uric Acid ◽  
Self Assembly ◽  
Multivariate Data Analysis ◽  
Covalent Modification ◽  
Carbon Electrode ◽  
Self Assembled Monolayer ◽  
Selective Determination ◽  
Highly Sensitive ◽  
Electrochemical Nanosensor

A highly sensitive electrochemical nanosensor was developed using covalent modification of a glassy carbon electrode (GCE) by self-assembly of a novel Schiff base.

Target-induced structure switching of DNA for label-free and ultrasensitive electrochemiluminescent detection of proteins

2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai
Keyword(s):  
Dna Structure ◽  
Label Free ◽  
Switching Strategy ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Exo Iii ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.

Unique quenching of fluorescent copper nanoclusters based on target-induced oxidation effect: a simple, label-free, highly sensitive and specific bleomycin assay

RSC Advances ◽  
2016 ◽  
Vol 6 (80) ◽  
pp. 76679-76683 ◽  
Author(s):  
Haiyin Li ◽  
Chuanfeng Wang ◽  
Panpan Gai ◽  
Ting Hou ◽  
Lei Ge ◽  
...  
Keyword(s):  
Label Free ◽  
Copper Nanoclusters ◽  
Highly Sensitive ◽  
Fluorescence Biosensor ◽  
Oxidation Effect

A novel label-free fluorescence biosensor for bleomycin (BLM) detection was developed by combining the excellent fluorescence behavior of copper nanoclusters (CuNCs) and the unique oxidation capability of BLM–Fe2+ complex toward CuNCs.

Encapsulation of hemin in Fe-based metal-organic frameworks and its application for the direct determination of aflatoxin M1

2021 ◽  
pp. 1-10
Author(s):  
F. Jahangiri-Dehaghani ◽  
H.R. Zare ◽  
Z. Shekari
Keyword(s):  
Electrochemical Impedance ◽  
Metal Organic Frameworks ◽  
Direct Determination ◽  
Differential Pulse ◽  
Aflatoxin M1 ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Selective Determination ◽  
Metal Organic

A label-free electrochemical aptasensor was constructed for the sensitive and selective determination of AFM1. For preparation of the aptasensor, the AFM1 aptamer was immobilised on the surface of a glassy carbon electrode modified with hemin encapsulated in Fe-based metal-organic frameworks (hemin@Fe-MIL-101). The morphology and the structure of Fe-MIL-101 and hemin@Fe-MIL-101 were evaluated by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction and Brunauer-Emmett-Teller-N2 sorption methods. Electrochemical impedance spectroscopy and cyclic voltammetry were performed to monitor the fabrication process of the electrochemical aptasensor. The electrochemical reduction current of hemin encapsulated in Fe-MIL-101 serves as a signal for the quantitative determination of AFM1. Differential pulse voltammetry was done to determine the AFM1 concentration in the linear range of 1.0×10-1-100.0 ng/ml. The detection limit of AFM1 was estimated to be 4.6×10-2 ng/ml. Finally, the fabricated aptasensor was applied to determine AFM1 in raw and boiled milk samples.

An Electrochemically Synthesized Nanoporous Copper Microsensor for Highly Sensitive and Selective Determination of Glyphosate

2020 ◽  
Vol 7 (7) ◽  
pp. 1558-1566 ◽  
Author(s):  
Matias Regiart ◽  
Abhishek Kumar ◽  
Josué M. Gonçalves ◽  
Gilberto J. Silva Junior ◽  
Jorge César Masini ◽  
...  
Keyword(s):  
Selective Determination ◽  
Nanoporous Copper ◽  
Highly Sensitive
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