A charge-switchable, four-armed polymeric photosensitizer for photodynamic cancer therapy

2014 ◽  
Vol 50 (33) ◽  
pp. 4354-4357 ◽  
Author(s):  
Chung-Sung Lee ◽  
Wooram Park ◽  
Young Um Jo ◽  
Kun Na
Keyword(s):  
Cancer Therapy ◽  
Water Soluble ◽  
New Class ◽  
Photodynamic Cancer Therapy ◽  
Ph Dependent ◽  
A Charge

A water-soluble, charge-switchable, four-armed polymeric photosensitizer (C4P-PS), in which charge switching is pH dependent, has been designed as a new class of photosensitizer for photodynamic cancer therapy.

Tumor-Activated Water-Soluble Photosensitizers for Near-Infrared Photodynamic Cancer Therapy

2018 ◽  
Vol 10 (19) ◽  
pp. 16335-16343 ◽  
Author(s):  
Hu Xiong ◽  
Kejin Zhou ◽  
Yunfeng Yan ◽  
Jason B. Miller ◽  
Daniel J. Siegwart
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Water Soluble ◽  
Photodynamic Cancer Therapy

Metal-Free Nanoassemblies of Water-Soluble Photosensitizer and Adenosine Triphosphate for Efficient and Precise Photodynamic Cancer Therapy

ACS Nano ◽  
2021 ◽  
Vol 15 (3) ◽  
pp. 4979-4988
Author(s):  
Zhiliang Li ◽  
Shukun Li ◽  
Yanhui Guo ◽  
Chengqian Yuan ◽  
Xuehai Yan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Adenosine Triphosphate ◽  
Water Soluble ◽  
Metal Free ◽  
Photodynamic Cancer Therapy

A singlet oxygen sensor for photodynamic cancer therapy

1999 ◽  
Author(s):  
Philip B. Keating ◽  
Michael F. Hinds ◽  
Steven J. Davis
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Oxygen Sensor ◽  
Photodynamic Cancer Therapy

Recent Advances in Developing Photosensitizers for Photodynamic Cancer Therapy

2017 ◽  
Vol 20 (5) ◽  
Author(s):  
Cong Chen ◽  
Jianmin Wang ◽  
Xiaoyan Li ◽  
Xiaolong Liu ◽  
Xiao Han
Keyword(s):  
Cancer Therapy ◽  
Recent Advances ◽  
Photodynamic Cancer Therapy

Hand-ground fullerene-nanodiamond composite for photosensitized water treatment and photodynamic cancer therapy

2021 ◽  
Vol 587 ◽  
pp. 101-109
Author(s):  
Hongshin Lee ◽  
Jung Seok Lee ◽  
Kyle J. Moor ◽  
Hyoung-il Kim ◽  
Sang-Ryoung Kim ◽  
...  
Keyword(s):  
Water Treatment ◽  
Cancer Therapy ◽  
Photodynamic Cancer Therapy

scholarly journals Combining Dextran Conjugates with Stimuli-Responsive and Folate-Targeting Activity: A New Class of Multifunctional Nanoparticles for Cancer Therapy

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1108
Author(s):  
Manuela Curcio ◽  
Alessandro Paolì ◽  
Giuseppe Cirillo ◽  
Sebastiano Di Pietro ◽  
Martina Forestiero ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Metastatic Cancer ◽  
Stimuli Responsive ◽  
Cancer Disease ◽  
New Class ◽  
Self Assembling ◽  
Redox Responsive ◽  
Potential Applicability ◽  
Mean Size

Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs. In this work, new dual pH/redox-responsive nanoparticles with affinity for folate receptors were prepared by the combination of two amphiphilic dextran (DEX) derivatives. DEXFA conjugate was obtained by covalent coupling of the polysaccharide with folic acid (FA), whereas DEXssPEGCOOH derived from a reductive amination step of DEX was followed by condensation with polyethylene glycol 600. After self-assembling, nanoparticles with a mean size of 50 nm, able to be destabilized in acidic pH and reducing media, were obtained. Doxorubicin was loaded during the self-assembling process, and the release experiments showed the ability of the proposed system to modulate the drug release in response to different pH and redox conditions. Finally, the viability and uptake experiments on healthy (MCF-10A) and metastatic cancer (MDA-MB-231) cells proved the potential applicability of the proposed system as a new drug vector in cancer therapy.

Novel triazole containing zinc(II)phthalocyanine Schiff bases: Determination of photophysical and photochemical properties for photodynamic cancer therapy

2021 ◽  
Vol 519 ◽  
pp. 120286
Author(s):  
Kevser Harmandar ◽  
Mehmet F. Saglam ◽  
Ibrahim F. Sengul ◽  
Gülçin Ekineker ◽  
Pelin Balcik-Ercin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Schiff Bases ◽  
Photodynamic Cancer Therapy ◽  
Photochemical Properties
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