Palladium catalyzed C3-arylation of 4-hydroxy-2-pyridones

The direct 3-arylation of 4-hydroxy-2-pyridones has been achieved for the first time by utilizing ligand free palladium(ii) catalysis under mild conditions.

Download Full-text

ChemInform Abstract: Ligand-Free Reusable Palladium-Catalyzed Heck-Type Coupling Reactions of Hypervalent Iodine Reagents under Mild Conditions.

ChemInform ◽

10.1002/chin.201136051 ◽

2011 ◽

Vol 42 (36) ◽

pp. no-no

Author(s):

Xiaoming Qu ◽

Peng Sun ◽

Tingyi Li ◽

Jincheng Mao

Keyword(s):

Hypervalent Iodine ◽

Coupling Reactions ◽

Mild Conditions ◽

Ligand Free ◽

Palladium Catalyzed ◽

Type Coupling

Download Full-text

Palladium catalyzed ligand-free Suzuki cross-coupling reactions of benzylic halides with aryl boronic acids under mild conditions

Tetrahedron Letters ◽

10.1016/j.tetlet.2004.07.073 ◽

2004 ◽

Vol 45 (37) ◽

pp. 6959-6962 ◽

Cited By ~ 67

Author(s):

B.P. Bandgar ◽

Sampada V. Bettigeri ◽

Jaywant Phopase

Keyword(s):

Cross Coupling ◽

Boronic Acids ◽

Coupling Reactions ◽

Mild Conditions ◽

Cross Coupling Reactions ◽

Ligand Free ◽

Palladium Catalyzed

Download Full-text

Ligand-Free and Solvent-Free Synthesis of 1,3-Disubstituted Naphthalenes through Stille Coupling

Synlett ◽

10.1055/s-0039-1690850 ◽

2020 ◽

Vol 31 (09) ◽

pp. 903-906

Author(s):

Taoufik Rohand ◽

Sanae Sbi ◽

Victor Mkpenie ◽

Kiyoshi Tanemura

Keyword(s):

Functional Groups ◽

Acetyl Chloride ◽

Stille Coupling ◽

Mechanistic Studies ◽

Major Step ◽

Mild Conditions ◽

Synthetic Strategy ◽

Ligand Free ◽

Palladium Catalyzed ◽

Solvent Free Synthesis

A variety of 1,3-disubstituted naphthalenes have been prepared by palladium-catalyzed annulation of (o-ethynylphenyl)acetyl chloride with design of a new synthetic strategy by Stille coupling using functionalized organostannanes. The method affords excellent yields of the substituted naphthalenes and accommodates a wide variety of functional groups under mild conditions. Mechanistic studies show intramolecular cyclization as a major step following C–C bond coupling.

Download Full-text

Palladium-Catalyzed Ligand-Free Suzuki Cross-Coupling Reactions of Benzylic Halides with Aryl Boronic Acids under Mild Conditions.

ChemInform ◽

10.1002/chin.200450058 ◽

2004 ◽

Vol 35 (50) ◽

Author(s):

B. P. Bandgar ◽

Sampada V. Bettigeri ◽

Jaywant Phopase

Keyword(s):

Cross Coupling ◽

Boronic Acids ◽

Coupling Reactions ◽

Mild Conditions ◽

Cross Coupling Reactions ◽

Ligand Free ◽

Palladium Catalyzed

Download Full-text

Synthesis of C3-alkylated benzofurans via palladium-catalyzed regiocontrolled hydro-furanization of unactivated alkenes

Organic Chemistry Frontiers ◽

10.1039/d0qo01247e ◽

2021 ◽

Vol 8 (1) ◽

pp. 127-132

Author(s):

Chi-Fan Zhu ◽

Cong-Hui Gao ◽

Wen-Juan Hao ◽

Yi-Long Zhu ◽

Shu-Jiang Tu ◽

...

Keyword(s):

Mild Conditions ◽

Wide Range ◽

Palladium Catalyzed ◽

First Time

A new chelation-controlled hydrofuranization of unactivated olefins with α-alkynyl arylols is reported for the first time, and used to produce a wide range of C3-alkylated benzofurans with generally good yields under mild conditions.

Download Full-text

Ligand-Free Reusable Palladium-Catalyzed Heck-Type Coupling Reactions of Hypervalent Iodine Reagents under Mild Conditions

Advanced Synthesis & Catalysis ◽

10.1002/adsc.201100008 ◽

2011 ◽

Vol 353 (7) ◽

pp. 1061-1066 ◽

Cited By ~ 29

Author(s):

Xiaoming Qu ◽

Peng Sun ◽

Tingyi Li ◽

Jincheng Mao

Keyword(s):

Hypervalent Iodine ◽

Coupling Reactions ◽

Mild Conditions ◽

Ligand Free ◽

Palladium Catalyzed ◽

Type Coupling

Download Full-text

A general and mild Cu-catalytic N-arylation of iminodibenzyls and iminostilbenes using unactivated aryl halides

RSC Advances ◽

10.1039/c7ra07437a ◽

2017 ◽

Vol 7 (78) ◽

pp. 49600-49604 ◽

Cited By ~ 2

Author(s):

Wubing Yao ◽

Bin Zhang ◽

Rongrong Li ◽

Huajiang Jiang ◽

Xiaoying Chen ◽

...

Keyword(s):

Aryl Halides ◽

Mild Conditions ◽

Highly Efficient ◽

Broad Scope ◽

Ligand Free ◽

First Time

A ligand-free, highly efficient Cu-catalyticN-arylation of iminodibenzyl and iminostilbene derivatives with a broad scope of unactivated aryl halides under mild conditions has been developed for the first time.

Download Full-text

First ligand-free, microwave-assisted, Heck cross-coupling reaction in pure water on a nucleoside – application to the synthesis of antiviral BVDU

RSC Advances ◽

10.1039/c4ra09798j ◽

2014 ◽

Vol 4 (87) ◽

pp. 46926-46929 ◽

Cited By ~ 30

Author(s):

Gwénaëlle Hervé ◽

Christophe Len

Keyword(s):

Pure Water ◽

Coupling Reaction ◽

Cross Coupling ◽

Microwave Assisted ◽

Cross Coupling Reaction ◽

Ligand Free ◽

Palladium Catalyzed ◽

Microwave Assistance ◽

First Time

For the first time, a palladium catalyzed Heck cross-coupling reaction between 5-iodo-2′-deoxyuridine and various acrylate derivatives was performed using ligand-free conditions and microwave assistance in pure water.

Download Full-text

Copper-Catalyzed Hydrocarboxylation of Allenes

10.26434/chemrxiv.7862456.v1 ◽

2019 ◽

Author(s):

Rémi blieck ◽

Marc Taillefer ◽

Florian Monnier

Keyword(s):

Carboxylic Acids ◽

Copper Catalysis ◽

Ligand Free ◽

First Time

The addition of carboxylic acids to allenes was performed for the first time with copper catalysis. The hydrocarboxylation reaction is totally regio- and stereoselective, ligand-free and used catalytic amounts of copper and base.

Download Full-text