scholarly journals Organizational metrics of interchromatin speckle factor domains: integrative classifier for stem cell adhesion & lineage signaling

2015 ◽  
Vol 7 (4) ◽  
pp. 435-446 ◽  
Author(s):  
Sebastián L. Vega ◽  
Anandika Dhaliwal ◽  
Varun Arvind ◽  
Parth J. Patel ◽  
Nick R. M. Beijer ◽  
...  
Keyword(s):  
Content Analysis ◽  
Stem Cell ◽  
Cell Adhesion ◽  
Nuclear Protein ◽  
Cell Lineage ◽  
Lineage Commitment ◽  
Cell Microenvironment ◽  
Stem Cell Lineage ◽  
High Content Analysis

Timely classification of stem cell lineage commitment in response to cell–microenvironment interactions using high content analysis of sub-nuclear protein organization.

mSEL-1L deficiency affects vasculogenesis and neural stem cell lineage commitment

2017 ◽  
Vol 233 (4) ◽  
pp. 3152-3163 ◽  
Author(s):  
Marina Cardano ◽  
Giuseppe R. Diaferia ◽  
Luciano Conti ◽  
Simona Baronchelli ◽  
Alessandro Sessa ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Lineage ◽  
Lineage Commitment ◽  
Stem Cell Lineage

scholarly journals GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment

Development ◽  
2014 ◽  
Vol 141 (20) ◽  
pp. e2005-e2005
Author(s):  
I.-H. Huang ◽  
C.-T. Hsiao ◽  
J.-C. Wu ◽  
R.-F. Shen ◽  
C.-Y. Liu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Focal Adhesion ◽  
Cell Lineage ◽  
Lineage Commitment ◽  
Stem Cell Lineage

scholarly journals Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

2004 ◽  
Vol 6 (4) ◽  
pp. 483-495 ◽  
Author(s):  
Rowena McBeath ◽  
Dana M Pirone ◽  
Celeste M Nelson ◽  
Kiran Bhadriraju ◽  
Christopher S Chen
Keyword(s):  
Stem Cell ◽  
Cell Shape ◽  
Cell Lineage ◽  
Lineage Commitment ◽  
Stem Cell Lineage ◽  
Cytoskeletal Tension

scholarly journals Biomimetic three-dimensional microenvironment for controlling stem cell fate

2011 ◽  
Vol 1 (5) ◽  
pp. 792-803 ◽  
Author(s):  
Hu Zhang ◽  
Sheng Dai ◽  
Jingxiu Bi ◽  
Kuo-Kang Liu
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Three Dimensional ◽  
Cell Lineage ◽  
Cell Interaction ◽  
Stem Cell Fate ◽  
Cell Microenvironment ◽  
Stem Cell Lineage ◽  
Matrix Cell ◽  
The Individual

Stem cell therapy is an emerging technique which is being translated into treatment of degenerated tissues. However, the success of translation relies on the stem cell lineage commitment in the degenerated regions of interest. This commitment is precisely controlled by the stem cell microenvironment. Engineering a biomimetic three-dimensional microenvironment enables a thorough understanding of the mechanisms of governing stem cell fate. We review the individual microenvironment components, including soluble factors, extracellular matrix, cell–cell interaction and mechanical stimulation. The perspectives in creating the biomimetic microenvironments are discussed with emerging techniques.

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