Proteasome inhibition and cytostatic effects on human cancer cells by pyrazolone-enamines: a combined crystallographic, structural and computational study

2015 ◽  
Vol 39 (3) ◽  
pp. 2168-2180 ◽  
Author(s):  
Xingchen Yan ◽  
Jiakun Xu ◽  
Xiaojing Wu ◽  
Zhongyu Zhang ◽  
Xia Zhang ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Cancer Cells ◽  
Computational Study ◽  
Human Cancer ◽  
Proteasome Inhibition ◽  
Human Cancer Cells

Interactions are possibly through hydrogen bonding of the pyrazolone ring and the hydroxyl, or the intercalation of conjugated plane.

Indirubin derivatives inhibit SFKs/Stat signaling associated with apoptosis in human cancer cells

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
S Nam ◽  
R Buettner ◽  
X Liu ◽  
J Turkson ◽  
D Kim ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Human Cancer Cells ◽  
Stat Signaling

Antiproliferation Effects of Germinated-Korean Rough Rice Extract on Human Cancer Cells

2010 ◽  
Vol 39 (3) ◽  
pp. 325-330 ◽  
Author(s):  
Hyun-Young Kim ◽  
In-Guk Hwang ◽  
Eun-Mi Joung ◽  
Tae-Myoung Kim ◽  
Dae-Joong Kim ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Human Cancer Cells ◽  
Rough Rice

Comprehensive Analysis and Prediction of the Essential Genes in Human Cancer Cells

2018 ◽  
Author(s):  
Yuwei Zhang ◽  
Yang Tao ◽  
Huihui Ji ◽  
Wei Li ◽  
Xingli Guo ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Comprehensive Analysis ◽  
Essential Genes ◽  
Human Cancer Cells
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