scholarly journals Characterizing nanoparticles in complex biological media and physiological fluids with depolarized dynamic light scattering

Nanoscale ◽  
2015 ◽  
Vol 7 (14) ◽  
pp. 5991-5997 ◽  
Author(s):  
S. Balog ◽  
L. Rodriguez-Lorenzo ◽  
C. A. Monnier ◽  
M. Obiols-Rabasa ◽  
B. Rothen-Rutishauser ◽  
...  
Keyword(s):  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Fluorescence Correlation Spectroscopy ◽  
Biological Fluids ◽  
Correlation Spectroscopy ◽  
Biological Media ◽  
Fluorescence Correlation ◽  
Depolarized Scattering

Characterization of NPs in physiological and biological fluids is challenging, yet can be met by using depolarized scattering, offering advantages over UV-Vis and fluorescence correlation spectroscopy.

scholarly journals Optical detection of gadolinium(iii) ions via quantum dot aggregation

RSC Advances ◽  
2017 ◽  
Vol 7 (40) ◽  
pp. 24730-24735 ◽  
Author(s):  
Steven D. Quinn ◽  
Steven W. Magennis
Keyword(s):  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Quantum Dot ◽  
Fluorescence Correlation Spectroscopy ◽  
Correlation Spectroscopy ◽  
Trivalent Metal ◽  
Fluorescence Correlation ◽  
Trivalent Metal Ions ◽  
Cdte Quantum Dot ◽  
Fluorescence Dynamic

CdTe quantum dot aggregation induced by trivalent metal ions is followed using fluorescence, dynamic light scattering and fluorescence correlation spectroscopy.

Characterization of Pteridines: a New Approach by Fluorescence Correlation Spectroscopy and Analysis of Assay Sensitivity

Pteridines ◽  
2001 ◽  
Vol 12 (4) ◽  
pp. 147-153 ◽  
Author(s):  
U. Demel ◽  
Z. Foldes-Papp ◽  
D. Fuchs ◽  
G. P. Tilz
Keyword(s):  
Single Molecule ◽  
Fluorescence Correlation Spectroscopy ◽  
Correlation Spectroscopy ◽  
Cell Mediated Immunity ◽  
Distribution Analysis ◽  
Assay Sensitivity ◽  
New Approach ◽  
Single Molecule Level ◽  
Fluorescence Correlation

Abstract In the present investigation, fluorescence con-elation spectroscopy (FCS) was used to measure the molecular motion of the pteridine derivative neopterin. However, technical limitations in the present optical setup precluded the identification of ,single neopterin molecules. FCS measurements with a fluorophore were also can-ied out for comparison. Exemplified by rhodamine green, we have introduced a concept that allows the detection, identification and analysis of assays in solution at the single-molecule level in tenns of bulk concentration. This concept is based on FCS and Poisson distribution analysis of assay sensitivity. The molecules had not to be quantified in a more concentrated fonn, or in flow and trapping experiments. The study demonstrated an ultrasensitive, reliable, rapid and direct tool for analytics and diagnostics in solution. We discuss a possible application of our new concept in activation control of cell-mediated immunity via neopterin determination.

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