Multiwall carbon nanotube-modified electrode as a nanosensor for electrochemical studies and stripping voltammetric determination of an antimalarial drug

A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linearity (over the concentration range from 0.1 to 700.0 μM), detection limit (65.0 nM), and reproducibility (RSD=2.5%) for a solution containing CD. Also, square wave voltammetry (SWV) was used for simultaneous determination of CD, folic acid (FA), and tryptophan (TRP) at the modified electrode. To further validate its possible application, the method was used for the quantification of CD, FA, and TRP in urine samples.

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Methylene Blue/Multiwall Carbon Nanotube Modified Electrode for the Amperometric Determination of Hydrogen Peroxide

Electroanalysis ◽

10.1002/elan.201100324 ◽

2011 ◽

Vol 23 (10) ◽

pp. 2290-2296 ◽

Cited By ~ 31

Author(s):

Roselyn C. Peña ◽

Mauro Bertotti ◽

Christopher M. A. Brett

Keyword(s):

Hydrogen Peroxide ◽

Methylene Blue ◽

Carbon Nanotube ◽

Modified Electrode ◽

Multiwall Carbon Nanotube ◽

Amperometric Determination ◽

Multiwall Carbon

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Voltammetric Determination of Homocysteine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of Chlorpromazine as a Mediator

Journal of Analytical Methods in Chemistry ◽

10.1155/2012/902184 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Fathali Gholami-Orimi ◽

Farshad Taleshi ◽

Pourya Biparva ◽

Hassan Karimi-Maleh ◽

Hadi Beitollahi ◽

...

Keyword(s):

Carbon Nanotube ◽

Dynamic Range ◽

Voltammetric Determination ◽

Multiwall Carbon Nanotube ◽

Catalytic Rate Constant ◽

Carbon Nanotube Paste Electrode ◽

Double Potential Step Chronoamperometry ◽

Paste Electrode ◽

Multiwall Carbon

We propose chlorpromazine (CHP) as a new mediator for the rapid, sensitive, and highly selective voltammetric determination of homocysteine (Hcy) using multiwall carbon nanotube paste electrode (MWCNTPE). The experimental results showed that the carbon nanotube paste electrode has a highly electrocatalytic activity for the oxidation of Hcy in the presence of CHP as a mediator. Cyclic voltammetry, double potential step chronoamperometry, and square wave voltammetry (SWV) are used to investigate the suitability of CHP at the surface of MWCNTPE as a mediator for the electrocatalytic oxidation of Hcy in aqueous solutions. The kinetic parameters of the system, including electron transfer coefficient, and catalytic rate constant were also determined using the electrochemical approaches. In addition, SWV was used for quantitative analysis. SWV showed wide linear dynamic range (0.1–210.0 μM Hcy) with a detection limit of 0.08 μM Hcy. Finally, this method was also examined as a selective, simple, and precise electrochemical sensor for the determination of Hcy in real samples.

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