A new calibration curve calculation method for absolute quantification of drug metabolizing enzymes in human liver microsomes by stable isotope dilution mass spectrometry

2015 ◽  
Vol 7 (14) ◽  
pp. 5934-5941 ◽  
Author(s):  
Huanhuan Wang ◽  
Haifeng Zhang ◽  
Jiabin Li ◽  
Junying Wei ◽  
Rui Zhai ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
Calibration Curve ◽  
Human Liver ◽  
Isotope Dilution Mass Spectrometry ◽  
Liver Microsomes ◽  
Absolute Quantification ◽  
Drug Metabolizing Enzymes ◽  
Metabolizing Enzymes ◽  
Stable Isotope Dilution

A new calibration curve calculation method in stable isotope dilution mass spectrometry for absolute quantification of drug metabolizing enzymes in human liver microsomes.

Use of SWATH-MS to relatively quantify the expression of hepatic drug metabolizing enzymes in human liver microsomes using a label-free approach

2018 ◽  
Vol 33 (1) ◽  
pp. S57-S58
Author(s):  
Rohitash Jamwal ◽  
Benjamin J. Barlock ◽  
Sravani Adusumalli ◽  
Ken Ogasawara ◽  
Brigitte L. Simons ◽  
...  
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Drug Metabolizing Enzymes ◽  
Label Free ◽  
Metabolizing Enzymes ◽  
Hepatic Drug
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