Development of a platform for single cell genomics using convex lens-induced confinement

Lab on a Chip ◽  
2015 ◽  
Vol 15 (14) ◽  
pp. 3013-3020 ◽  
Author(s):  
Sara Mahshid ◽  
Mohammed Jalal Ahamed ◽  
Daniel Berard ◽  
Susan Amin ◽  
Robert Sladek ◽  
...  
Keyword(s):  
Single Cell ◽  
Base Pair ◽  
Single Cell Analysis ◽  
Lab On A Chip ◽  
Cell Analysis ◽  
Next Generation ◽  
Single Cell Genomics ◽  
Convex Lens ◽  
Genomic Dnas

We present a lab-on-a-chip for the next generation of single-cell genomics, performing full-cycle single-cell analysis by demonstrating mega-base pair genomic DNAs in nanochannels extracted in situ.

Microfluidic positioning of pollen grains in lab-on-a-chip for single cell analysis

2014 ◽  
Vol 117 (4) ◽  
pp. 504-511 ◽  
Author(s):  
Mahmood Ghanbari ◽  
Amir Sanati Nezhad ◽  
Carlos G. Agudelo ◽  
Muthukumaran Packirisamy ◽  
Anja Geitmann
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Pollen Grains ◽  
Lab On A Chip ◽  
Cell Analysis

scholarly journals SpliceRCA: in Situ Single-Cell Analysis of mRNA Splicing Variants

2018 ◽  
Vol 4 (6) ◽  
pp. 680-687 ◽  
Author(s):  
Xiaojun Ren ◽  
Ruijie Deng ◽  
Kaixiang Zhang ◽  
Yupeng Sun ◽  
Xucong Teng ◽  
...  
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Mrna Splicing ◽  
Cell Analysis ◽  
Splicing Variants

The next frontier in single cell analysis: multimodal studies and clinical translation

Lab on a Chip ◽  
2019 ◽  
Vol 19 (21) ◽  
pp. 3573-3574 ◽  
Author(s):  
Pratip K. Chattopadhyay ◽  
Daniel T. Chiu
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Lab On A Chip ◽  
Clinical Translation ◽  
Cell Analysis ◽  
Thought Leaders

Thought leaders Pratip Chattopadhyay and Daniel Chiu introduce the Lab on a Chip single cell analysis thematic collection.

scholarly journals Symposium on single cell analysis and genomic approaches, Experimental Biology 2017 Chicago, Illinois, April 23, 2017

2017 ◽  
Vol 49 (9) ◽  
pp. 491-495
Author(s):  
Hilary A. Coller
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Single Cells ◽  
Experimental Biology ◽  
Intratumor Heterogeneity ◽  
Cell Analysis ◽  
Single Cell Genomics ◽  
Critical Issues ◽  
Cell To Cell Variability ◽  
External Stimuli

Emerging technologies for the analysis of genome-wide information in single cells have the potential to transform many fields of biology, including our understanding of cell states, the response of cells to external stimuli, mosaicism, and intratumor heterogeneity. At Experimental Biology 2017 in Chicago, Physiological Genomics hosted a symposium in which five leaders in the field of single cell genomics presented their recent research. The speakers discussed emerging methodologies in single cell analysis and critical issues for the analysis of single cell data. Also discussed were applications of single cell genomics to understanding the different types of cells within an organism or tissue and the basis for cell-to-cell variability in response to stimuli.

scholarly journals In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer

2015 ◽  
Vol 47 (10) ◽  
pp. 1212-1219 ◽  
Author(s):  
Michalina Janiszewska ◽  
Lin Liu ◽  
Vanessa Almendro ◽  
Yanan Kuang ◽  
Cloud Paweletz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Pik3ca Mutation ◽  
Cell Analysis ◽  
Her2 Amplification ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Positive Breast Cancer

Magnetic Force-based Lab-on-a-chip for Single Cell Analysis in a Droplet

2019 ◽  
Vol 16 (17) ◽  
pp. 15-20 ◽  
Author(s):  
Mina Okochi ◽  
Hiroyoshi Tsuchiya ◽  
Fumitaka Kumazawa ◽  
Mitsuhiro Shikida ◽  
Hiroyuki Honda
Keyword(s):  
Single Cell ◽  
Magnetic Force ◽  
Single Cell Analysis ◽  
Lab On A Chip ◽  
Cell Analysis
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