scholarly journals Gold-catalyzed three-component spirocyclization: a one-pot approach to functionalized pyrazolidines

2016 ◽  
Vol 14 (5) ◽  
pp. 1579-1583 ◽  
Author(s):  
Bernd Wagner ◽  
Wolf Hiller ◽  
Hiroaki Ohno ◽  
Norbert Krause
Keyword(s):  
One Pot ◽  
Highly Efficient ◽  
Three Component Coupling

From simple to complex: The highly efficient gold-catalyzed three-component coupling of an alkynol, a hydrazine and an aldehyde or ketone affords hitherto unknown spirocyclic pyrazolidines.

Facile Access to 3,4-Disubstituted 2H-Chromenes via Domino [4+2] Annulation

Synthesis ◽  
2020 ◽  
Author(s):  
Sure Siva Prasad ◽  
Dirgha Raj Joshi ◽  
Ikyon Kim
Keyword(s):  
Lewis Acid ◽  
Triethyl Phosphite ◽  
Synthetic Route ◽  
One Pot ◽  
Highly Efficient ◽  
Three Component Coupling

AbstractA highly efficient synthetic route to polysubstituted 2H-chromenes was developed utilizing a domino O-alkylation/intramolecular Horner–Wadsworth–Emmons (HWE) olefination of diarylmethylphosphonates, which were readily accessed via Lewis acid mediated one-pot three-component coupling of aldehydes, phenols, and triethyl phosphite.

Manganese(ii) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

RSC Advances ◽  
2014 ◽  
Vol 4 (50) ◽  
pp. 26301-26308 ◽  
Author(s):  
Shakil N. Afraj ◽  
Chinpiao Chen ◽  
Gene-Hsian Lee
Keyword(s):  
Efficient Method ◽  
Cycloaddition Reaction ◽  
Coupling Reaction ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Co Catalyst ◽  
Free Condition ◽  
Highly Efficient ◽  
Solvent Free Condition ◽  
Three Component Coupling

A one-pot green and highly efficient method for the synthesis of propargylamines and distereoselective synthesis of fused triazoles via three-component coupling in the presence of manganese(ii) chloride and a catalyst-free 1,3-dipolar cycloaddition reaction without using a co-catalyst is reported.

Catalysis by metal–organic frameworks: proline and gold functionalized MOFs for the aldol and three-component coupling reactions

RSC Advances ◽  
2014 ◽  
Vol 4 (25) ◽  
pp. 13093-13107 ◽  
Author(s):  
Liu Lili ◽  
Zhang Xin ◽  
Rang Shumin ◽  
Yang Ying ◽  
Dai Xiaoping ◽  
...  
Keyword(s):  
Aldol Reaction ◽  
Metal Organic Frameworks ◽  
Coupling Reaction ◽  
Coupling Reactions ◽  
One Pot ◽  
Postsynthetic Modification ◽  
Highly Efficient ◽  
Synthetic Strategy ◽  
Metal Organic ◽  
Three Component Coupling

Homochiral MOFs were engineered using postsynthetic modification and a one-pot synthetic strategy. l-Proline functionalized IRMOF-3 show high ee for aldol reaction. Gold functionalized CUP-1 catalysts are highly efficient for the A3 coupling reaction.

Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones

2013 ◽  
Vol 10 (10) ◽  
pp. 764-769 ◽  
Author(s):  
Akbar Mobinikhaledi ◽  
Alireza Amiri
Keyword(s):  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis

Iodine Catalyzed Highly Efficient One Pot Three Component Synthesis of 4-arylidene-3-methylisoxazol-5 (4H) -one in Aqueous Medium

2018 ◽  
Vol 5 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Srinivas L. Nakkalwar ◽  
Shivaji B. Patwari ◽  
Mohasim M. Patel ◽  
Vivekanand B. Jadhav
Keyword(s):  
Aqueous Medium ◽  
One Pot ◽  
Highly Efficient

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

2021 ◽  
Vol 76 (2) ◽  
pp. 85-90
Author(s):  
Abdolkarim Zare ◽  
Manije Dianat
Keyword(s):  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Amount ◽  
Green Protocol ◽  
Highly Efficient ◽  
Green Approach ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields

Abstract A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium chloride ([Et3N–SO3H][Cl]) as an ionic liquid (IL) catalyst under solvent-free conditions afforded the mentioned compounds in high yields and short reaction times. Our protocol is superior to many of the reported protocols in terms of two or more of these factors: the reaction times, yields, conditions (solvent-free versus usage of organic solvents), temperature and catalyst amount.

Highly efficient protocol for one-pot N-alkylation of nucleobases using alcohols in bmim[Br]: a rapid route to access acyclic nucleosides

2015 ◽  
Vol 12 (9) ◽  
pp. 1603-1612 ◽  
Author(s):  
Mohammad Navid Soltani Rad ◽  
Somayeh Behrouz ◽  
Elham Zarenezhad ◽  
Narjes Kaviani
Keyword(s):  
One Pot ◽  
Highly Efficient ◽  
Acyclic Nucleosides
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