A label-free electrochemical immunosensor for carcinoembryonic antigen detection on a graphene platform doped with poly(3,4-ethylenedioxythiophene)/Au nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (106) ◽  
pp. 86910-86918 ◽  
Author(s):  
Yan-Sha Gao ◽  
Jing-Kun Xu ◽  
Li-Min Lu ◽  
Xiao-Fei Zhu ◽  
Wen-Min Wang ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Au Nanoparticles ◽  
Electrochemical Immunosensor ◽  
Antigen Detection ◽  
Label Free ◽  
Step Method ◽  
Sensing Platform

In this work, a two-step method was developed for the fabrication of a graphene sensing platform doped with poly(3,4-ethylenedioxythiophene)/Au nanoparticles (AuNPs/PEDOT/GR).

A Label-Free Electrochemical Immunosensor for Carcinoembryonic Antigen Based on Graphene and Thionine

2013 ◽  
Vol 643 ◽  
pp. 29-32 ◽  
Author(s):  
Jing Man Han ◽  
Zhan Fang Ma
Keyword(s):  
Carcinoembryonic Antigen ◽  
Glassy Carbon ◽  
Electrode Surface ◽  
Au Nanoparticles ◽  
Electrochemical Immunosensor ◽  
Carbon Electrode ◽  
Label Free ◽  
Optimal Conditions ◽  
Redox Species ◽  
Electrode Surfaces

A label-free immunosensor was developed to detect the presence of an antigen. This immunosensor was based on the modulation of the electrochemistry of the surface bound redox species thionine (Thi). The model antigen was carcinoembryonic antigen (CEA) and the model epitope was the antibody of CEA (anti-CEA). Glassy carbon electrode surfaces were first drop-coated with a mixture of graphene, Thi and Nafion and air-dried. The electrode surface was then electrodeposited in HAuCl4solution to form Au nanoparticles (AuNPs). The resulted AuNPs were used to immobilize anti-CEA. Binding of CEA to the surface bound epitope resulted in the attenuation of the Thi electrochemistry. Under optimal conditions, the response of the label-free immunosensor had a liner range from 10 fg/mL to 100 ng/mL with a detection of 3.5 fg/mL (S/N=3).

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Multi-walled carbon nanotubes–chitosan with a branched structure modified with ferrocenecarboxylic acid for carcinoembryonic antigen detection

2015 ◽  
Vol 7 (23) ◽  
pp. 10032-10039 ◽  
Author(s):  
Taotao Feng ◽  
Xiuwen Qiao ◽  
Haining Wang ◽  
Zhao Sun ◽  
Chenglin Hong
Keyword(s):  
Carbon Nanotubes ◽  
Carcinoembryonic Antigen ◽  
Modified Electrode ◽  
Electrochemical Immunosensor ◽  
Antigen Detection ◽  
Multi Walled Carbon Nanotubes ◽  
Ferrocenecarboxylic Acid ◽  
Branched Structure ◽  
Walled Carbon Nanotubes

A novel electrochemical immunosensor for the detection of CEA was proposed based on Fc-COOH connected to the branched structure of a MWCNT–CS complex modified electrode.

A label-free photoelectrochemical immunosensor for carcinoembryonic antigen detection based on a g-C3N4/CdSe nanocomposite

The Analyst ◽  
2021 ◽  
Vol 146 (1) ◽  
pp. 146-155
Author(s):  
Xing-Pei Liu ◽  
Jing-Shuai Chen ◽  
Chang-Jie Mao ◽  
Bao-Kang Jin
Keyword(s):  
Carcinoembryonic Antigen ◽  
Antigen Detection ◽  
Label Free

Herein, a label-free photoelectrochemical immunosensor based on a g-C3N4/CdSe nanocomposite was established and applied to detect carcinoembryonic antigen (CEA).

Highly-sensitive label-free electrochemical carcinoembryonic antigen immunosensor based on a novel Au nanoparticles–graphene–chitosan nanocomposite cryogel electrode

2015 ◽  
Vol 853 ◽  
pp. 521-532 ◽  
Author(s):  
Saluma Samanman ◽  
Apon Numnuam ◽  
Warakorn Limbut ◽  
Proespichaya Kanatharana ◽  
Panote Thavarungkul
Keyword(s):  
Carcinoembryonic Antigen ◽  
Au Nanoparticles ◽  
Label Free ◽  
Highly Sensitive

A highly sensitive label-free electrochemical immunosensor based on an aligned GaN nanowires array/polydopamine heterointerface modified with Au nanoparticles

2019 ◽  
Vol 7 (9) ◽  
pp. 1442-1449 ◽  
Author(s):  
Qingyun Liu ◽  
Taotao Yang ◽  
Yongqin Ye ◽  
Ping Chen ◽  
Xiaoning Ren ◽  
...  
Keyword(s):  
Au Nanoparticles ◽  
Nanowire Array ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Array Configuration ◽  
Gan Nanowires ◽  
Nanowire Surface ◽  
Highly Sensitive ◽  
Gan Nanowire ◽  
Nanowires Array

Taking advantage of a nanowire array configuration and a semiconductor/polymer heterointerface, a highly sensitive label-free electrochemical immunosensor was developed through integration of polydopamine on an aligned GaN nanowire surface.

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