scholarly journals The influence of selected NSAIDs on volume phase transition in poly(2-(2-methoxyethoxy)ethyl methacrylate) hydrogels

2016 ◽  
Vol 4 (8) ◽  
pp. 1528-1534 ◽  
Author(s):  
Magdalena N. Olejniczak ◽  
Krzysztof Piechocki ◽  
Marcin Kozanecki ◽  
Kaloian Koynov ◽  
Agnieszka Adamus ◽  
...  

Hydrogels exhibiting Volume Phase Transition (VPT) are considered as useful biomaterials for the preparation of various drug delivery systems.

Polymer ◽  
2017 ◽  
Vol 110 ◽  
pp. 25-35 ◽  
Author(s):  
Marcin Pastorczak ◽  
Lidia Okrasa ◽  
Jeong Ae Yoon ◽  
Tomasz Kowalewski ◽  
Krzysztof Matyjaszewski

2016 ◽  
Vol 7 (10) ◽  
pp. 1913-1921 ◽  
Author(s):  
Yefei Tian ◽  
Shanshan Bian ◽  
Wuli Yang

We developed a redox degradable P(MEO2MA-s-s-OEGMA) nanogel with tunable volume phase transition temperature for drug delivery via precipitation polymerization using a disulfide-containing crosslinker.


Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.


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