Dual pH-responsive 5-aminolevulinic acid pseudopolyrotaxane prodrug micelles for enhanced photodynamic therapy

Novel 5-aminolevulinic acid (ALA) pseudopolyrotaxane prodrug micelles with dual pH-responsive properties were prepared by the host–guest interaction of α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG).

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5-aminolevulinic acid-incorporated nanoparticles of methoxy poly(ethylene glycol)-chitosan copolymer for photodynamic therapy

International Journal of Nanomedicine ◽

10.2147/ijn.s39615 ◽

2013 ◽

pp. 809 ◽

Cited By ~ 34

Author(s):

Chung-Wook Chung ◽

Chung ◽

Young-IL Jeong ◽

Dae Hwan Kang

Keyword(s):

Photodynamic Therapy ◽

Ethylene Glycol ◽

Aminolevulinic Acid ◽

Poly Ethylene Glycol ◽

Glycol Chitosan ◽

Poly Ethylene

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Core – Shell pH-Responsive Poly(Vinylpyrrolidone)-Block-Poly(Ethylene Glycol)-Block-Poly(Methacrylic Acid) Coated Magnetic Nanoparticle as a Carrier for Delivery of Poorly Water-Soluble Lovastatin

Pharmaceutical Chemistry Journal ◽

10.1007/s11094-017-1562-y ◽

2017 ◽

Vol 51 (1) ◽

pp. 81-90

Author(s):

Naghi Saadatjou ◽

Hanif Fattahi

Keyword(s):

Ethylene Glycol ◽

Methacrylic Acid ◽

Magnetic Nanoparticle ◽

Water Soluble ◽

Core Shell ◽

Ph Responsive ◽

Poly Ethylene Glycol ◽

Poorly Water Soluble ◽

Poly Ethylene

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pH-responsive poly(ethylene glycol)-poly(ϵ-caprolactone)-poly(glutamic acid) polymersome as an efficient doxorubicin carrier for cancer therapy

Polymer International ◽

10.1002/pi.5416 ◽

2017 ◽

Vol 66 (11) ◽

pp. 1579-1586 ◽

Cited By ~ 4

Author(s):

Lanxia Zhao ◽

Xia Zhang ◽

Xin Liu ◽

Juan Li ◽

Yuxia Luan

Keyword(s):

Cancer Therapy ◽

Ethylene Glycol ◽

Glutamic Acid ◽

Ph Responsive ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Development of chlorin e6-conjugated poly(ethylene glycol)-poly(d,l-lactide) nanoparticles for photodynamic therapy

Nanomedicine ◽

10.2217/nnm-2018-0255 ◽

2019 ◽

Vol 14 (7) ◽

pp. 819-834 ◽

Cited By ~ 7

Author(s):

Preeti Kumari ◽

Sri Vishnu Kiran Rompicharla ◽

Himanshu Bhatt ◽

Balaram Ghosh ◽

Swati Biswas

Keyword(s):

Photodynamic Therapy ◽

Ethylene Glycol ◽

Chlorin E6 ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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One-shot synthesis and solution properties of ROS/pH responsive methoxy poly(ethylene glycol)-b-polycarbonate

Polymer Chemistry ◽

10.1039/c9py00060g ◽

2019 ◽

Vol 10 (17) ◽

pp. 2143-2151 ◽

Cited By ~ 5

Author(s):

Yan Zhang ◽

Yue Xu ◽

Chao Wei ◽

Chuanhao Sun ◽

Bingkun Yan ◽

...

Keyword(s):

Ethylene Glycol ◽

Tertiary Amine ◽

Solution Properties ◽

Ph Responsive ◽

Poly Ethylene Glycol ◽

Amine Groups ◽

Poly Ethylene

A one-shot method was employed to synthesize ROS/pH responsive methoxy poly(ethylene glycol)-b-polycarbonate (mPEG-b-poly(MN-co-MSe)) with the selenide and tertiary amine groups situated on the backbone.

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Chlorin e6 Conjugated Methoxy-Poly(Ethylene Glycol)-Poly(D,L-Lactide) Glutathione Sensitive Micelles for Photodynamic Therapy

Pharmaceutical Research ◽

10.1007/s11095-019-2750-0 ◽

2020 ◽

Vol 37 (2) ◽

Cited By ~ 2

Author(s):

Preeti Kumari ◽

Milan Paul ◽

Himanshu Bhatt ◽

Sri Vishnu Kiran Rompicharla ◽

Debolina Sarkar ◽

...

Keyword(s):

Photodynamic Therapy ◽

Ethylene Glycol ◽

Chlorin E6 ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Star-shaped poly(l-lactide)-b-poly(ethylene glycol) with porphyrin core: synthesis, self-assembly, drug-release behavior and singlet oxygen research

New Journal of Chemistry ◽

10.1039/c3nj01621h ◽

2014 ◽

Vol 38 (8) ◽

pp. 3569-3578 ◽

Cited By ~ 17

Author(s):

Xiao-Hui Dai ◽

Zhi-Ming Wang ◽

Lu-You Gao ◽

Jian-Ming Pan ◽

Xiao-Hong Wang ◽

...

Keyword(s):

Photodynamic Therapy ◽

Block Copolymer ◽

Drug Release ◽

Ethylene Glycol ◽

Self Assembly ◽

Release Behavior ◽

Poly Ethylene Glycol ◽

Drug Release Behavior ◽

Porphyrin Core ◽

Poly Ethylene

pH-induced block copolymer SPPLA-b-PEG with porphyrin core for photodynamic therapy.

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A Tunable pH-Responsive Nanomaterials for Cancer Delivery

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.750-752.1476 ◽

2013 ◽

Vol 750-752 ◽

pp. 1476-1479 ◽

Cited By ~ 1

Author(s):

Bin Liu ◽

Guan Hui Gao ◽

Peng Liu ◽

Hu Qiang Yi ◽

Wei Wei ◽

...

Keyword(s):

Drug Delivery ◽

Ethylene Glycol ◽

Potential Application ◽

Ph Responsive ◽

Poly Ethylene Glycol ◽

Positive Potential ◽

Ph Values ◽

Drugs In Blood ◽

Poly Ethylene

In this paper, we successfully designed a pH-responsive micelles based on hybrid polypeptide copolymers of poly (L-lysine-4-Azepan-1-yl-butyric)-b-poly (ethylene glycol)-b-poly (L-lysine-Diisopropylamide)-b-poly (L-leucine) (PLL(A)-PEG-PLL(B)-PLLeu) for efficient drug delivery. This pH-responsive nanoparticles were able to response to different pH values (pH=6.8 and 5.5). In vitro, these nanoparticles exhibited a stable and evenly distributed approximately 51 nm, a slightly positive potential about 10.3 mv at pH 7.4, which were crucial for the circulation of drugs in blood. While size and potential were about 130 nm and 34.7 mv at pH 6.8, which were good for drugs in membrane. Furthermore, the loading capability of DOX was up to 11.3%, and the pH-responsive release efficiency reached to 68.3% at pH 5.5. The results indicated that these micelles had huge potential application in cancer delivery.

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