Quantitative proteomic analysis of milk fat globule membrane (MFGM) proteins in human and bovine colostrum and mature milk samples through iTRAQ labeling

2016 ◽  
Vol 7 (5) ◽  
pp. 2438-2450 ◽  
Author(s):  
Mei Yang ◽  
Min Cong ◽  
Xiuming Peng ◽  
Junrui Wu ◽  
Rina Wu ◽  
...  

Milk fat globule membrane (MFGM) proteins have many functions.

2019 ◽  
Vol 10 (7) ◽  
pp. 4256-4268 ◽  
Author(s):  
Weixuan Li ◽  
Mohan Li ◽  
Xueyan Cao ◽  
Mei Yang ◽  
Hongjiao Han ◽  
...  

The composition and functions of milk fat globule membrane (MFGM) proteins are important indicators of the nutritional quality of milk.


2019 ◽  
Vol 10 (8) ◽  
pp. 5046-5058 ◽  
Author(s):  
Xueyan Cao ◽  
Yan Zheng ◽  
Shangyi Wu ◽  
Ning Yang ◽  
Junrui Wu ◽  
...  

Comparison of MFGM N-glycoproteomes among human and bovine colostrum and mature milk reveals diverse compositions and biological functions among them.


2016 ◽  
Vol 209 ◽  
pp. 10-16 ◽  
Author(s):  
Jing Lu ◽  
Lu Liu ◽  
Xiaoyang Pang ◽  
Shuwen Zhang ◽  
Zhenhu Jia ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Wei Jia ◽  
Rong Zhang ◽  
Zhenbao Zhu ◽  
Lin Shi

Large variations in the bioactivities and composition of milk fat globule membrane (MFGM) proteins were observed between Saanen dairy goat and Holstein bovine at various lactation periods. In the present study, 331, 250, 182, and 248 MFGM proteins were characterized in colostrum and mature milk for the two species by Q-Orbitrap HRMS-based proteomics techniques. KEGG pathway analyses displayed that differentially expressed proteins in colostrum involved in galactose metabolism and an adipogenesis pathway, and the differentially expressed proteins in mature milk associated with lipid metabolism and a PPAR signaling pathway. These results indicated that the types and functions of MFGM proteins in goat and bovine milk were different, and goat milk had a better function of fatty acid metabolism and glucose homeostasis, which can enhance our understanding of MFGM proteins in these two species across different lactation periods, and they provide significant information for the study of lipid metabolism and glycometabolism of goat milk.


2013 ◽  
Vol 32 (2) ◽  
pp. 110-120 ◽  
Author(s):  
Thien Trung Le ◽  
Griet Debyser ◽  
William Gilbert ◽  
Karin Struijs ◽  
John Van Camp ◽  
...  

2020 ◽  
Vol 103 (4) ◽  
pp. 3017-3024 ◽  
Author(s):  
Yuxue Sun ◽  
Cuina Wang ◽  
Xiaomeng Sun ◽  
Shilong Jiang ◽  
Mingruo Guo

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