scholarly journals Alarms about structural alerts

2016 ◽  
Vol 18 (16) ◽  
pp. 4348-4360 ◽  
Author(s):  
Vinicius M. Alves ◽  
Eugene N. Muratov ◽  
Stephen J. Capuzzi ◽  
Regina Politi ◽  
Yen Low ◽  
...  

Integrative approach for safety assessment of new chemicals by combining structural alerts and QSAR models.

2021 ◽  
Vol 18 ◽  
pp. 100167
Author(s):  
Prachi Pradeep ◽  
Richard Judson ◽  
David M. DeMarini ◽  
Nagalakshmi Keshava ◽  
Todd M. Martin ◽  
...  

2016 ◽  
Vol 67 (3) ◽  
pp. 169-182 ◽  
Author(s):  
Alja Plošnik ◽  
Marjan Vračko ◽  
Marija Sollner Dolenc

Abstract Knowing the mutagenic and carcinogenic properties of chemicals is very important for their hazard (and risk) assessment. One of the crucial events that trigger genotoxic and sometimes carcinogenic effects is the forming of adducts between chemical compounds and nucleic acids and histones. This review takes a look at the mechanisms related to specific functional groups (structural alerts or toxicophores) that may trigger genotoxic or epigenetic effects in the cells. We present up-to-date information about defined structural alerts with their mechanisms and the software based on this knowledge (QSAR models and classification schemes).


2020 ◽  
Vol 5 (1) ◽  
pp. 290-303
Author(s):  
P. Charlie Buckley ◽  
Kimberly A. Murza ◽  
Tami Cassel

Purpose The purpose of this study was to explore the perceptions of special education practitioners (i.e., speech-language pathologists, special educators, para-educators, and other related service providers) on their role as communication partners after participation in the Social Communication and Engagement Triad (Buckley et al., 2015 ) yearlong professional learning program. Method A qualitative approach using interviews and purposeful sampling was used. A total of 22 participants who completed participation in either Year 1 or Year 2 of the program were interviewed. Participants were speech-language pathologists, special educators, para-educators, and other related service providers. Using a grounded theory approach (Glaser & Strauss, 1967 ) to data analysis, open, axial, and selective coding procedures were followed. Results Three themes emerged from the data analysis and included engagement as the goal, role as a communication partner, and importance of collaboration. Conclusions Findings supported the notion that educators see the value of an integrative approach to service delivery, supporting students' social communication and engagement across the school day but also recognizing the challenges they face in making this a reality.


2019 ◽  
Vol 25 ◽  
pp. 173
Author(s):  
Magnus Löndahl ◽  
Mona Landin-Olsson ◽  
Stig Attval ◽  
Colleen Mdingi ◽  
Katherine S Tweden
Keyword(s):  

1984 ◽  
Vol 29 (1) ◽  
pp. 6-8
Author(s):  
Gayla Margolin

1993 ◽  
Vol 38 (2) ◽  
pp. 158-158
Author(s):  
George V. Rebec

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