Matrix effects in Pb/U measurements during LA-ICP-MS analysis of the mineral apatite

2016 ◽  
Vol 31 (6) ◽  
pp. 1206-1215 ◽  
Author(s):  
Jay Thompson ◽  
Sebastien Meffre ◽  
Roland Maas ◽  
Vadim Kamenetsky ◽  
Maya Kamenetsky ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Reference Materials ◽  
Isotope Dilution ◽  
Matrix Effects ◽  
Primary Standard ◽  
Isotope Dilution Mass Spectrometry ◽  
Ms Analysis ◽  
Icp Ms

U–Pb ages of several apatite reference materials, acquired by LA-ICP-MS over a 3.5 year period using the Otter Lake apatite as a primary standard, show systematic offsets (up to 3%) from reference ages obtained by isotope dilution mass spectrometry.

scholarly journals Preparation and characterisation of an 57Fe enriched haemoglobin spike material for species-specific isotope dilution mass spectrometry

2016 ◽  
Vol 31 (9) ◽  
pp. 1846-1857 ◽  
Author(s):  
C. Brauckmann ◽  
C. Frank ◽  
D. Schulze ◽  
P. Kaiser ◽  
R. Stosch ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Isotope Dilution ◽  
Isotope Dilution Mass Spectrometry ◽  
Icp Ms ◽  
Species Specific

A species-specific ID-ICP-MS method for intact haemoglobin was developed applying an 57Fe enriched haemoglobin spike, which was prepared and characterised carefully.

A Method for the Routine Determination of Methylmercury in Marine Tissue by GC Isotope Dilution-ICP-MS

2012 ◽  
Vol 95 (4) ◽  
pp. 1189-1194 ◽  
Author(s):  
Stig Valdersnes ◽  
Amund Maage ◽  
Daniel Fliegel ◽  
Kåre Julshamn
Keyword(s):  
Reference Material ◽  
Reference Materials ◽  
Isotope Dilution ◽  
Isotope Dilution Mass Spectrometry ◽  
Standard Reference Materials ◽  
Statistical Measures ◽  
Icp Ms ◽  
Wide Range ◽  
Z Scores

Abstract Currently, there is no legal limit for methyl mercury (MeHg) in food; thus, no standardized method for the determination of MeHg in seafood exists within the European jurisdiction. In anticipation of a future legislative limit an inductively coupled plasma isotope dilution mass spectrometry (GC-ICP-ID-MS) method was developed in collaboration with the European Standardization Organization (CEN). The method comprises spiking the tissue sample with Me201Hg, followed by decomposition with tetramethylammonium hydroxide, pH adjustment and derivatization with sodium tetraethylborate, and finally organic extraction of the derivatized MeHg in a hexane phase. Subsequently, the sample is analyzed via GC-ICP-MS and the result calculated using the ID equation. The working range of the method was 0.0005–1.321 mg/kg MeHg in marine tissue, with an internal reproducibility (RSD) of 12–1%. The method was validated based on statistical measures, such as the z-scores, using the commercially available reference materials from National Institute of Standards and Technology Standard Reference Material (NIST SRM) 1566b, NIST SRM 2977 and National Research Council of Canada (NRCC) TORT 2, NRCC, DORM 3, NRCC DOLT 4, and European Reference Material (ERM) CE 464. Z-scores for all standard reference materials, except for NIST SRM 1566b, were better than |1.5|. The wide range of marine tissues used during the validation ensures that the method will be applicable for measuring of MeHg in seafood matrixes of all kinds.

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