Structure–activity relationship of novel macrocyclic biased apelin receptor agonists

2017 ◽  
Vol 15 (2) ◽  
pp. 449-458 ◽  
Author(s):  
Alexandre Murza ◽  
Xavier Sainsily ◽  
Jérôme Côté ◽  
Laurent Bruneau-Cossette ◽  
Élie Besserer-Offroy ◽  
...  
Keyword(s):  
G Protein ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
G Protein Coupled Receptor ◽  
Endogenous Ligand ◽  
Structure Activity ◽  
Apelin Receptor ◽  
Relationship Of ◽  
G Protein Coupled ◽  
Cardiovascular Functions

Apelin is the endogenous ligand for the G protein-coupled receptor APJ and exerts a key role in regulating cardiovascular functions.

Modulation of l-α-lysophosphatidylinositol/GPR55 MAP kinase signalling by CB2 receptor agonists: identifying novel GPR55 inhibitors

2016 ◽  
Vol 27 (3) ◽  
Author(s):  
Sharon Anavi-Goffer ◽  
Andrew J. Irving ◽  
Ruth A. Ross
Keyword(s):  
Map Kinase ◽  
G Protein ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Cb2 Receptor ◽  
Structure Activity ◽  
Endogenous Lipid ◽  
Lipid Sensing ◽  
Relationship Study ◽  
G Protein Coupled

AbstractGPR55 is a lipid-sensing G protein-coupled receptor that is activated by the endogenous lipidIn this study we investigated the GPR55 activity of four synthetic CBHere we show that the CBThis structure-activity-relationship study has identified novel ligands which act both as CB

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Leishmania Amazonensis ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽  
2008 ◽  
Vol 74 (03) ◽  
Author(s):  
N Kasanah ◽  
AG Shilabin ◽  
DE Wedge ◽  
MT Hamann
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Fusarium Spp ◽  
Structure Activity ◽  
Kahalalide F ◽  
Relationship Of
Sign in / Sign up

Export Citation Format

Share Document