Structural insight into inhibition of human Class II PI3K isoforms: homology modeling, binding site characterization, docking and molecular dynamics studies

RSC Advances ◽  
2016 ◽  
Vol 6 (113) ◽  
pp. 112455-112467 ◽  
Author(s):  
Vikash Kumar ◽  
Mohammad Imran Siddiqi
Keyword(s):  
Molecular Dynamics ◽  
Homology Modeling ◽  
Cell Survival ◽  
Therapeutic Intervention ◽  
Class Ii ◽  
Human Class ◽  
Lipid Kinases ◽  
Structural Insight ◽  
Insight Into

Phosphoinositide-3-kinases (PI3Ks) are family of lipid kinases, involved in cell survival, growth and proliferation. Role of Class II PI3Ks in cancer is emerging and gaining importance for the therapeutic intervention.

The Role of Human Class II Molecules in Activation of T4 Lymphocytes

1986 ◽  
pp. 473-488 ◽  
Author(s):  
E. Qvigstad ◽  
Ø. Bruserud ◽  
E. Thorsby
Keyword(s):  
Class Ii ◽  
Human Class

scholarly journals Insight into the Role of Water on the Methylation of Hexamethylbenzene in H‐SAPO‐34 from First Principle Molecular Dynamics Simulations

ChemCatChem ◽  
2019 ◽  
Vol 11 (16) ◽  
pp. 3993-4010 ◽  
Author(s):  
Simon Bailleul ◽  
Sven M. J. Rogge ◽  
Louis Vanduyfhuys ◽  
Veronique Van Speybroeck
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
First Principle ◽  
Dynamics Simulations ◽  
Insight Into
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