Triple-helix molecular switch-induced hybridization chain reaction amplification for developing a universal and sensitive electrochemical aptasensor

RSC Advances ◽  
2016 ◽  
Vol 6 (93) ◽  
pp. 90310-90317 ◽  
Author(s):  
Qiaoqiao Liu ◽  
Jinquan Liu ◽  
Dinggeng He ◽  
Taiping Qing ◽  
Xiaoxiao He ◽  
...  
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Hybridization Chain Reaction ◽  
Electrochemical Aptasensor ◽  
Chain Reaction ◽  
Reaction Amplification

In this work, a universal and sensitive “signal-on” electrochemical aptasensor platform has been developed based on a triple-helix molecular switch (THMS)-induced hybridization chain reaction (HCR) amplification.

Establishment of a universal and sensitive plasmonic biosensor platform based on the hybridization chain reaction (HCR) amplification induced by a triple-helix molecular switch

The Analyst ◽  
2020 ◽  
Vol 145 (11) ◽  
pp. 3864-3870
Author(s):  
Ganglin Wang ◽  
Jingfeng Li ◽  
Yong He ◽  
Jun Liu ◽  
Mingxia Yu ◽  
...  
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Plasmonic Sensing

Here, we have reported a universal and sensitive plasmonic sensing strategy for biomolecule assays by coupling the hybridization chain reaction (HCR) strategy and a triple-helix molecular switch.

ICP-MS DNA assay based on lanthanide labels and hybridization chain reaction amplification

2015 ◽  
Vol 7 (14) ◽  
pp. 5767-5771 ◽  
Author(s):  
Chong Deng ◽  
Chong-Hua Zhang ◽  
Hao Tang ◽  
Jian-Hui Jiang
Keyword(s):  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Dna Assay ◽  
Icp Ms ◽  
Reaction Amplification

A novel ICP MS DNA assay based on lanthanide labels and hybridization chain reaction amplification has been developed.

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