scholarly journals Two rare meroterpenoidal rotamers from Ganoderma applanatum

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3413-3418 ◽  
Author(s):  
Qi Luo ◽  
Zheng-Chao Tu ◽  
Yong-Xian Cheng
Keyword(s):  
Natural Product ◽  
Fruiting Bodies ◽  
Ganoderma Applanatum

Applanatumols Z3 (1) and Z4 (2), two novel natural product hybrids consisting of a meroterpenoid and a glycerol and three known compounds (3–5) were isolated from the fruiting bodies of the fungus Ganoderma applanatum.

scholarly journals Shushe Acids A-D from Ganoderma Applanatum

2017 ◽  
Vol 12 (3) ◽  
pp. 1934578X1701200
Author(s):  
Qi Luo ◽  
Yan-Jiao Zhang ◽  
Zhi-Qiang Shen ◽  
Peng Chen ◽  
Yong-Xian Cheng
Keyword(s):  
Succinic Acid ◽  
Natural Product ◽  
Gallic Acid ◽  
Spectroscopic Methods ◽  
Fruiting Bodies ◽  
Ganoderma Applanatum ◽  
Prevention And Treatment ◽  
New Compounds ◽  
Derivatives Of ◽  
Mcf 7

Ganoderma applanatum is a fungus used for the prevention and treatment of a variety of disorders in China. In the present study, four new compounds, named shushe acids A-D (1-4), were isolated from the fruiting bodies of this species. Their structures were identified on the basis of spectroscopic methods. Compounds 1-4 are all natural product hybrids composed of derivatives of gallic acid, glycerol and succinic acid. None of the four compounds showed activity against the MCF-7 cell line.

scholarly journals Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2895
Author(s):  
Hitomi Sasaki ◽  
Yuzuru Kubohara ◽  
Hirotaka Ishigaki ◽  
Katsunori Takahashi ◽  
Hiromi Eguchi ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Secondary Metabolites ◽  
Natural Product ◽  
Inhibitory Activity ◽  
Osteoclast Differentiation ◽  
Fruiting Bodies ◽  
Slime Molds ◽  
Cellular Slime ◽  
Cellular Slime Molds ◽  
Product Chemistry

We report a protoilludane-type sesquiterpene, mucoroidiol, and a geranylated bicyclogermacranol, firmibasiol, isolated from Dictyostelium cellular slime molds. The methanol extracts of the fruiting bodies of cellular slime molds were separated by chromatographic methods to give these compounds. Their structures have been established by several spectral means. Mucoroidiol and firmibasiol are the first examples of more modified and oxidized terpenoids isolated from cellular slime molds. Mucoroidiol showed moderate osteoclast-differentiation inhibitory activity despite demonstrating very weak cell-proliferation inhibitory activity. Therefore, cellular slime molds produce considerably diverse secondary metabolites, and they are promising sources of new natural product chemistry.

Pigments of Fungi. LII Anisochiral Flavomannin 6,6′,8-Tri-O-methyl Ether from an Australian Dermocybe Toadstool

1999 ◽  
Vol 52 (8) ◽  
pp. 749 ◽  
Author(s):  
Malcolm S. Buchanan ◽  
Melvyn Gill ◽  
Alberto Gimenez ◽  
Somphone Phonh-Axa ◽  
Evelin Raudies ◽  
...  
Keyword(s):  
Natural Product ◽  
Methyl Ether ◽  
Absolute Configuration ◽  
Enantiomeric Purity ◽  
Chemical Degradation ◽  
Spectroscopic Methods ◽  
Fruiting Bodies ◽  
The Absolute

Flavomannin 6,6′,8-tri-O-methyl ether occurs in the fruiting bodies of the Australian toadstool Dermocybe sp. WAT 24274 as an anisochiral mixture of the (3S,3′S,P)- and (3R,3′R,M)-enantiomers (5) and (7), respectively, in which the former predominates to the extent of 50% e.e. The structure of the natural product is determined by spectroscopic methods and the absolute configuration and enantiomeric purity are deduced from the c.d. spectrum and by chemical degradation of the natural product to a mixture of stereoisomeric dihydroanthracenones that has been analysed by chiral h.p.l.c.

scholarly journals Aldose Reductase Inhibitors from the Fruiting Bodies of Ganoderma applanatum

2005 ◽  
Vol 28 (6) ◽  
pp. 1103-1105 ◽  
Author(s):  
Sanghyun Lee ◽  
Sang Hee Shim ◽  
Ju Sun Kim ◽  
Kuk Hyun Shin ◽  
Sam Sik Kang
Keyword(s):  
Aldose Reductase ◽  
Fruiting Bodies ◽  
Ganoderma Applanatum ◽  
Aldose Reductase Inhibitors ◽  
Reductase Inhibitors

Antimicrobial lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum

2021 ◽  
pp. 1-7
Author(s):  
Jing-Xia Shi ◽  
Guo-Yu Chen ◽  
Qian Sun ◽  
Shi-Yang Meng ◽  
Wei-Qun Chi
Keyword(s):  
Fruiting Bodies ◽  
Ganoderma Applanatum

Benzopyran-4-one Derivatives from the Fungus Ganoderma applanatum

2007 ◽  
Vol 62 (10) ◽  
pp. 1329-1332 ◽  
Author(s):  
Fei Wang ◽  
Ze-Jun Dong ◽  
Ji-Kai Liu
Keyword(s):  
Nmr Spectra ◽  
Spectroscopic Analysis ◽  
Fruiting Bodies ◽  
Ganoderma Applanatum ◽  
New Compounds

Two new benzopyran-4-one derivatives, applanatins A (1) and B (2), were isolated from the fruiting bodies of the fungus Ganoderma applanatum (Ganodermataceae), along with one known analogue, ganoderma aldehyde (3), as well as four known ganoderenic acids. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis. The partial assignments of the NMR spectra of 3 were also revised.

scholarly journals (±)-Applanatumines B–D: novel dimeric meroterpenoids from Ganoderma applanatum as inhibitors of JAK3

RSC Advances ◽  
2017 ◽  
Vol 7 (60) ◽  
pp. 38037-38043 ◽  
Author(s):  
Qi Luo ◽  
Zhen Wang ◽  
Jin-Feng Luo ◽  
Zheng-Chao Tu ◽  
Yong-Xian Cheng
Keyword(s):  
Fruiting Bodies ◽  
Ganoderma Applanatum

Applanatumines B–D (1–3), three pairs of dimeric meroterpenoid enantiomers featuring the presence of a 6-oxo-4,4a,5,5a,6,8,8a,8b-octahydrofuro[3′,4′:4,5]cyclopenta[1,2-b]pyran-3-carbaldehyde structure core, were isolated from the fruiting bodies of Ganoderma applanatum.

scholarly journals Inhibition of Degranulation of RBL-2H3 Cells by Extracts and Compounds from Armillaria ostoyae

2017 ◽  
Vol 4 (01) ◽  
pp. e1-e7 ◽  
Author(s):  
Simon Merdivan ◽  
Kristina Jenett-Siems ◽  
Karsten Siems ◽  
Timo Niedermeyer ◽  
Michael Solis ◽  
...  
Keyword(s):  
Methyl Linoleate ◽  
Natural Product ◽  
Fruiting Bodies ◽  
Inhibiting Effect ◽  
Armillaria Ostoyae ◽  
The Family ◽  
First Time

Abstract Armillaria ostoyae (Romagn.) Herink is an edible honey mushroom from the family Physalacriaceae (Agaricales, Basidiomycota). Dichloromethane extracts of mushroom mycelium and fruiting bodies exhibited a significant degranulation inhibiting effect on RBL-2H3 cells using noncytotoxic concentrations. Bioactivity-guided fractionation of the mycelial dichloromethane extract led to the isolation of sesquiterpen aryl esters. Methyl linoleate could also be isolated. These substances were obtained from A. ostoyae for the first time, with one compound representing an undescribed natural product. Purified compounds melleolide H and J inhibited degranulation significantly. A. ostoyae could be a candidate for support of allergy treatments.

Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum

2019 ◽  
Vol 157 ◽  
pp. 103-110 ◽  
Author(s):  
XingRong Peng ◽  
Lei Li ◽  
JinRun Dong ◽  
ShuangYang Lu ◽  
Jing Lu ◽  
...  
Keyword(s):  
Fruiting Bodies ◽  
Ganoderma Applanatum
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