An enzyme free electrochemical biosensor for sensitive detection of miRNA with a high discrimination factor by coupling the strand displacement reaction and catalytic hairpin assembly recycling

The Analyst ◽  
2017 ◽  
Vol 142 (21) ◽  
pp. 4116-4123 ◽  
Author(s):  
Juan Yao ◽  
Zhang Zhang ◽  
Zhenghua Deng ◽  
Youqiang Wang ◽  
Yongcan Guo

Sensitive and selective detection of miRNA based on the toehold-mediated strand displacement reaction (SDR) and non-enzymatic catalytic hairpin reaction (CHA) recycling.

2019 ◽  
Vol 11 (12) ◽  
pp. 1613-1619 ◽  
Author(s):  
Yujian Li ◽  
Xiaojuan Ding ◽  
Dandan Li ◽  
Haiping Wu ◽  
Wei Huang ◽  
...  

In this study, a homogeneous fluorescent biosensing strategy is described for the detection of DNA based on an entropy-driven strand displacement reaction and DNAzyme.


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